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Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2004 | Pubmed ID: 15466696
The zebrafish as a model of heart regeneration.
Cloning and stem cells , 2004 | Pubmed ID: 15671662
Expression and purification of a human, soluble Arylsulfatase A for Metachromatic Leukodystrophy enzyme replacement therapy.
Journal of biotechnology May, 2005 | Pubmed ID: 15862354
Wnt signalling regulates adult hippocampal neurogenesis.
Nature Oct, 2005 | Pubmed ID: 16251967
Metabolic correction in oligodendrocytes derived from metachromatic leukodystrophy mouse model by using encapsulated recombinant myoblasts.
Journal of the neurological sciences Apr, 2007 | Pubmed ID: 17341424
Synapse formation on neurons born in the adult hippocampus.
Nature neuroscience Jun, 2007 | Pubmed ID: 17486101
In vivo fate analysis reveals the multipotent and self-renewal capacities of Sox2+ neural stem cells in the adult hippocampus.
Cell stem cell Nov, 2007 | Pubmed ID: 18371391
Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes.
Nature biotechnology Nov, 2008 | Pubmed ID: 18931654
Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats.
Learning & memory (Cold Spring Harbor, N.Y.) Feb, 2009 | Pubmed ID: 19181621
Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells.
Nature Jul, 2009 | Pubmed ID: 19483674
Derivation of human embryonic stem cells at the Center of Regenerative Medicine in Barcelona.
In vitro cellular & developmental biology. Animal Apr, 2010 | Pubmed ID: 20177997
A protocol describing the genetic correction of somatic human cells and subsequent generation of iPS cells.
Nature protocols Apr, 2010 | Pubmed ID: 20224565
Rem2 GTPase maintains survival of human embryonic stem cells as well as enhancing reprogramming by regulating p53 and cyclin D1.
Genes & development Mar, 2010 | Pubmed ID: 20231315
Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus.
Cell stem cell Jul, 2010 | Pubmed ID: 20621052
In vivo demonstration that alpha-synuclein oligomers are toxic.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2011 | Pubmed ID: 21325059
Increased dosage of tumor suppressors limits the tumorigenicity of iPS cells without affecting their pluripotency.
Aging cell Feb, 2012 | Pubmed ID: 21981310
ER signaling regulation drives the switch between autophagy and apoptosis in NRK-52E cells exposed to cisplatin.
Experimental cell research Feb, 2012 | Pubmed ID: 22146761
Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease.
EMBO molecular medicine May, 2012 | Pubmed ID: 22407749
Cyclin A1 is essential for setting the pluripotent state and reducing tumorigenicity of induced pluripotent stem cells.
Stem cells and development Oct, 2012 | Pubmed ID: 22500553
Interplay of LRRK2 with chaperone-mediated autophagy.
Nature neuroscience Apr, 2013 | Pubmed ID: 23455607
Induced pluripotent stem cell-based studies of Parkinson's disease: challenges and promises.
CNS & neurological disorders drug targets Dec, 2013 | Pubmed ID: 24040813
MT5-MMP regulates adult neural stem cell functional quiescence through the cleavage of N-cadherin.
Nature cell biology Jul, 2014 | Pubmed ID: 24952463
Cardiac disease modeling using induced pluripotent stem cell-derived human cardiomyocytes.
World journal of stem cells Mar, 2015 | Pubmed ID: 25815118
Using iPS Cells toward the Understanding of Parkinson's Disease.
Journal of clinical medicine , 2015 | Pubmed ID: 26239346
Activity and High-Order Effective Connectivity Alterations in Sanfilippo C Patient-Specific Neuronal Networks.
Stem cell reports Oct, 2015 | Pubmed ID: 26411903
Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients.
EMBO molecular medicine , 2015 | Pubmed ID: 26516212
1Cell Division and Cancer Group, Spanish National Cancer Research Centre (CNIO),
2, Centro de Investigaciones Biomédicas en Red sobre Enfermedades Neurodegenerativas (CIBERNED),
3Departmento de Biologìa Celular, Universidad de Valencia,
4, Institut de Biomedicina de la Universitat de Barcelona (IBUB),
5Department of Molecular and Translational Medicine, Fibroblast Reprogramming Unit, University of Brescia
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