Stem Cell Fate Laboratory
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Lack of sik1 in mouse embryonic stem cells impairs cardiomyogenesis by down-regulating the cyclin-dependent kinase inhibitor p57kip2.
PloS one , 2010 | Pubmed ID: 20140255
Molecular integration of casanova in the Nodal signalling pathway controlling endoderm formation.
Development (Cambridge, England) Jan, 2002 | Pubmed ID: 11807021
Cripto: a tumor growth factor and more.
Journal of cellular physiology Mar, 2002 | Pubmed ID: 11857442
Role of the EGF-CFC gene cripto in cell differentiation and embryo development.
Gene Apr, 2002 | Pubmed ID: 11992720
Nodal-dependent Cripto signaling promotes cardiomyogenesis and redirects the neural fate of embryonic stem cells.
The Journal of cell biology Oct, 2003 | Pubmed ID: 14581455
Cripto as a target for improving embryonic stem cell-based therapy in Parkinson's disease.
Stem cells (Dayton, Ohio) Apr, 2005 | Pubmed ID: 15790767
Nodal-dependant Cripto signaling in ES cells: from stem cells to tumor biology.
Oncogene Aug, 2005 | Pubmed ID: 16123800
Chemical synthesis of mouse cripto CFC variants.
Proteins Aug, 2006 | Pubmed ID: 16752415
Cripto signaling in differentiating embryonic stem cells.
Methods in molecular biology (Clifton, N.J.) , 2006 | Pubmed ID: 16845990
Solution structure of mouse Cripto CFC domain and its inactive variant Trp107Ala.
Journal of medicinal chemistry Nov, 2006 | Pubmed ID: 17125258
Cripto promotes A-P axis specification independently of its stimulatory effect on Nodal autoinduction.
The Journal of cell biology Feb, 2008 | Pubmed ID: 18268105
High-throughput screening-compatible single-step protocol to differentiate embryonic stem cells in neurons.
Stem cells and development Jun, 2008 | Pubmed ID: 18576914
Cripto recruits Furin and PACE4 and controls Nodal trafficking during proteolytic maturation.
The EMBO journal Oct, 2008 | Pubmed ID: 18772886
Cripto localizes Nodal at the limiting membrane of early endosomes.
Science signaling Nov, 2008 | Pubmed ID: 19001664
Qualitative and quantitative proteomic profiling of cripto(-/-) embryonic stem cells by means of accurate mass LC-MS analysis.
Journal of proteome research Feb, 2009 | Pubmed ID: 19152270
G protein-coupled receptor APJ and its ligand apelin act downstream of Cripto to specify embryonic stem cells toward the cardiac lineage through extracellular signal-regulated kinase/p70S6 kinase signaling pathway.
Circulation research Jul, 2009 | Pubmed ID: 19574549
Cripto-1 is required for hypoxia to induce cardiac differentiation of mouse embryonic stem cells.
The American journal of pathology Nov, 2009 | Pubmed ID: 19834060
A small synthetic cripto blocking Peptide improves neural induction, dopaminergic differentiation, and functional integration of mouse embryonic stem cells in a rat model of Parkinson's disease.
Stem cells (Dayton, Ohio) Aug, 2010 | Pubmed ID: 20641036
The FoxO3/type 2 deiodinase pathway is required for normal mouse myogenesis and muscle regeneration.
The Journal of clinical investigation Nov, 2010 | Pubmed ID: 20978344
Control of embryonic stem cell metastability by L-proline catabolism.
Journal of molecular cell biology Apr, 2011 | Pubmed ID: 21307025
An automated high throughput screening-compatible assay to identify regulators of stem cell neural differentiation.
Molecular biotechnology Mar, 2012 | Pubmed ID: 21553282
Temporal proteomic profiling of embryonic stem cell secretome during cardiac and neural differentiation.
Proteomics Oct, 2011 | Pubmed ID: 21770033
Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2012 | Pubmed ID: 23129614
The G-protein-coupled receptor APJ is expressed in the second heart field and regulates Cerberus-Baf60c axis in embryonic stem cell cardiomyogenesis.
Cardiovascular research Oct, 2013 | Pubmed ID: 23787002
The class I-specific HDAC inhibitor MS-275 modulates the differentiation potential of mouse embryonic stem cells.
Biology open , 2013 | Pubmed ID: 24167717
L-Proline induces a mesenchymal-like invasive program in embryonic stem cells by remodeling H3K9 and H3K36 methylation.
Stem cell reports , 2013 | Pubmed ID: 24319666
Cardiomyogenesis is controlled by the miR-99a/let-7c cluster and epigenetic modifications.
Stem cell research Mar, 2014 | Pubmed ID: 24365598
Hhex and Cer1 mediate the Sox17 pathway for cardiac mesoderm formation in embryonic stem cells.
Stem cells (Dayton, Ohio) Jun, 2014 | Pubmed ID: 24585688
Intracellular inactivation of thyroid hormone is a survival mechanism for muscle stem cell proliferation and lineage progression.
Cell metabolism Dec, 2014 | Pubmed ID: 25456740
Conditional Cripto overexpression in satellite cells promotes myogenic commitment and enhances early regeneration.
Frontiers in cell and developmental biology , 2015 | Pubmed ID: 26052513
Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency.
Nature communications Sep, 2016 | Pubmed ID: 27586544
Tracking the evolution of epialleles during neural differentiation and brain development: D-Aspartate oxidase as a model gene.
Epigenetics Nov, 2016 | Pubmed ID: 27858532
Vitamin C and l-Proline Antagonistic Effects Capture Alternative States in the Pluripotency Continuum.
Stem cell reports Dec, 2016 | Pubmed ID: 28017658
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