Joachim Scholz

Reaction of Ketones with 1,4-Diaza-1,3-diene Zirconium and Hafnium Complexes: First Example of a 1,3-Dipolar Cycloaddition Reaction of 1,4-Diaza-1,3-diene Complexes of Early Transition Metals.

1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) and related derivatives: chemistry and biochemical effects on catecholamine biosynthesis.

Modification of tyrosine hydroxylase activity by chloral derived beta-carbolines in vitro.

Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord.

Hsp27 upregulation and phosphorylation is required for injured sensory and motor neuron survival.

Can we conquer pain?

Modeled ligand-protein complexes elucidate the origin of substrate specificity and provide insight into catalytic mechanisms of phenylalanine hydroxylase and tyrosine hydroxylase.

Reduction of a 1-aza-1,3-diene to a 1-azabut-2-ene-1,4-diyl dianion: an unusual reaction course.

Blocking caspase activity prevents transsynaptic neuronal apoptosis and the loss of inhibition in lamina II of the dorsal horn after peripheral nerve injury.

GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence.

Using screening tools to identify neuropathic pain.

Complement induction in spinal cord microglia results in anaphylatoxin C5a-mediated pain hypersensitivity.

The neuropathic pain triad: neurons, immune cells and glia.

Low-dose methotrexate reduces peripheral nerve injury-evoked spinal microglial activation and neuropathic pain behavior in rats.

Endogenous tetrahydroisoquinolines associated with Parkinson's disease mimic the feedback inhibition of tyrosine hydroxylase by catecholamines.

A novel tool for the assessment of pain: validation in low back pain.

Neuropathic pain: a maladaptive response of the nervous system to damage.

Preclinical research on persistent postsurgical pain: what we don't know, but should start studying.

Peripheral nerve injury produces a sustained shift in the balance between glutamate release and uptake in the dorsal horn of the spinal cord.