Mark W. Grinstaff

Solid-Phase Synthesis and Photophysical Properties of DNA Labeled at the Nucleobase with Ru(bpy)(2)(4-m-4'-pa-bpy)(2+).

Electrophilic Aromatic Substitution. 13.(1) Kinetics and Spectroscopy of the Chloromethylation of Benzene and Toluene with Methoxyacetyl Chloride or Chloromethyl Methyl Ether and Aluminum Chloride in Nitromethane or Tin Tetrachloride in Dichloromethane. The Methoxymethyl Cation as a Remarkably Selective Common Electrophile.

Automated Solid-Phase Synthesis of Site-Specifically Labeled Ruthenium-Oligonucleotides.

The Alkylation of Iodouridine by a Heterogeneous Palladium Catalyst.

Synthesis and characterization of phenothiazine labeled oligodeoxynucleotides: novel 2'-deoxyadenosine and thymidine probes for labeling DNA.

Direct-writing of polymer nanostructures: poly(thiophene) nanowires on semiconducting and insulating surfaces.

A photopolymerized sealant for corneal lacerations.

Hybrid dendritic-linear polyester-ethers for in situ photopolymerization.

Synthesis and characterization of carbohydrate-based phospholipids.

Nucleobase and 5'-terminal probes for DNA redox chemistry.

Synthesis and characterization of a dianionic carbohydrate-based phospholipid.

Biodendrimers: new polymeric biomaterials for tissue engineering.

Synthesis and characterization of pi-stacked phenothiazine-labeled oligodeoxynucleotides.

Intramolecular electrocatalysis of 8-oxo-guanine oxidation: secondary structure control of electron transfer in osmium-labeled oligonucleotides.

Engineering porcine arteries: effects of scaffold modification.

The convergent synthesis of poly(glycerol-succinic acid) dendritic macromolecules.

Dendritic molecular capsules for hydrophobic compounds.

Photocrosslinkable hyaluronan as a scaffold for articular cartilage repair.

New dendritic adhesives for sutureless ophthalmic surgical procedures: in vitro studies of corneal laceration repair.

Supramolecular assemblies of nucleoside phosphocholine amphiphiles.

Conformationally gated electrochemical gene detection.

DNA-PEG-DNA triblock macromolecules for reagentless DNA detection.

Charge-reversal amphiphiles for gene delivery.

Dendritic macromers as in situ polymerizing biomaterials for securing cataract incisions.

Supramolecular assemblies of DNA with neutral nucleoside amphiphiles.

Nucleic acid complexing glycosyl nucleoside-based amphiphile.

Novel tissue adhesives to secure laser in situ keratomileusis flaps.

Dendritic supramolecular assemblies for drug delivery.

Synthesis and aqueous aggregation properties of amphiphilic surface-block dendrimers.

Biodendrimer-based hydrogel scaffolds for cartilage tissue repair.

Cationic nucleoside lipids for gene delivery.

Self-assembled microspheres from f-block elements and nucleoamphiphiles.

Probing the electronic structure of platinum(II) chromophores: crystal structures, NMR structures, and photophysical properties of six new bis- and di- phenolate/thiolate Pt(II)diimine chromophores.

Hydrogels formed by multiple peptide ligation reactions to fasten corneal transplants.

Peptide-PEG amphiphiles as cytophobic coatings for mammalian and bacterial cells.

Nucleoside phosphocholine amphiphile for in vitro DNA transfection.

In situ polymerized hydrogels for repairing scleral incisions used in pars plana vitrectomy procedures.

Dendrimer-encapsulated camptothecins: increased solubility, cellular uptake, and cellular retention affords enhanced anticancer activity in vitro.

Immobilized hydrogels for screening of molecular interactions.

Photo cross-linkable Biodendrimers as ophthalmic adhesives for central lacerations and penetrating keratoplasties.

Designing hydrogel adhesives for corneal wound repair.

Non-viral charge reversal vectors for pDNA delivery.

Lipophilic peptides for gene delivery.

Amphiphilic copolymer for delivery of xenobiotics: in vivo studies in a freshwater invertebrate, a Mesostominae flatworm.

A new helper phospholipid for gene delivery.

Nucleoside, nucleotide and oligonucleotide based amphiphiles: a successful marriage of nucleic acids with lipids.

Therapeutic and diagnostic applications of dendrimers for cancer treatment.

Prevention of local tumor growth with paclitaxel-loaded microspheres.

Two-dimensional self-assembly and complementary base-pairing between amphiphile nucleotides on graphite.

Synthesis and properties of supramolecular ionic networks.

Enzymatic release of a surface-adsorbed RGD therapeutic from a cleavable peptide anchor.

Hydrogels for osteochondral repair based on photocrosslinkable carbamate dendrimers.

Anionic amphiphilic dendrimers as antibacterial agents.

Real time imaging of supramolecular assembly formation via programmed nucleolipid recognition.

The development of peptide-based interfacial biomaterials for generating biological functionality on the surface of bioinert materials.

Cationic nucleoside lipids based on a 3-nitropyrrole universal base for siRNA delivery.

Expansile nanoparticles: synthesis, characterization, and in vivo efficacy of an acid-responsive polymeric drug delivery system.

Comparison of sutures and dendritic polymer adhesives for corneal laceration repair in an in vivo chicken model.

Directed assembly of PEGylated-peptide coatings for infection-resistant titanium metal.

Anionic nucleotide--lipids for in vitro DNA transfection.

Effect of contrast agent charge on visualization of articular cartilage using computed tomography: exploiting electrostatic interactions for improved sensitivity.

Prevention of local tumor recurrence following surgery using low-dose chemotherapeutic polymer films.

Prevention of in vivo lung tumor growth by prolonged local delivery of hydroxycamptothecin using poly(ester-carbonate)-collagen composites.

Peptide interfacial biomaterials improve endothelial cell adhesion and spreading on synthetic polyglycolic acid materials.

The effect of charge-reversal amphiphile spacer composition on DNA and siRNA delivery.

Silver nanoparticle-catalyzed Diels-Alder cycloadditions of 2'-hydroxychalcones.

Cationic nucleoside lipids derived from universal bases: A rational approach for siRNA transfection.

Nanotechnology in thoracic surgery.

Ease of synthesis, controllable sizes, and in vivo large-animal-lymph migration of polymeric nanoparticles.

Staphylococcus aureus resistance on titanium coated with multivalent PEGylated-peptides.

Biomedical applications of dendrimers: a tutorial.

Acidic polysaccharide mimics via ring-opening metathesis polymerization.

The performance of expansile nanoparticles in a murine model of peritoneal carcinomatosis.

A versatile reagent to synthesize diverse ionic liquids ranging from small molecules and dendrimers to functionalized proteins.

Bioactive stent surface coating that promotes endothelialization while preventing platelet adhesion.

Reduction-triggered delivery using nucleoside-lipid based carriers possessing a cleavable PEG coating.

Synthesis and characterization of dendron cross-linked PEG hydrogels as corneal adhesives.

Cationic contrast agents improve quantification of glycosaminoglycan (GAG) content by contrast enhanced CT imaging of cartilage.

Paclitaxel-loaded expansile nanoparticles delay local recurrence in a heterotopic murine non-small cell lung cancer model.

Synthesis, characterization, and in vitro transfection activity of charge-reversal amphiphiles for DNA delivery.

Functional lipids and lipoplexes for improved gene delivery.

Paclitaxel-eluting polymer film reduces locoregional recurrence and improves survival in a recurrent sarcoma model: a novel investigational therapy.

Synthesis, characterization, and in vitro evaluation of a hydrogel-based corneal onlay.

Paclitaxel-loaded expansile nanoparticles in a multimodal treatment model of malignant mesothelioma.

Biocompatible and bioactive surface modifications for prolonged in vivo efficacy.

Tunable pores for measuring concentrations of synthetic and biological nanoparticle dispersions.

MRT letter: Contrast-enhanced computed tomographic imaging of soft callus formation in fracture healing.

Hydrogels as intracellular depots for drug delivery.

Exploiting Dendrimer Multivalency To Combat Emerging and Re-Emerging Infectious Diseases.

Local drug delivery strategies for cancer treatment: gels, nanoparticles, polymeric films, rods, and wafers.

Nanoparticle migration and delivery of Paclitaxel to regional lymph nodes in a large animal model.

Diphosphonium Ionic Liquids as Broad-Spectrum Antimicrobial Agents.

Functionalized hydrophobic poly(glycerol-co-ε-caprolactone) depots for controlled drug release.

Superhydrophobic materials for tunable drug release: using displacement of air to control delivery rates.

Charge-reversal lipids, peptide-based lipids, and nucleoside-based lipids for gene delivery.

Formation of supramolecular systems via directed Nucleoside-Lipid recognition.

3D superhydrophobic electrospun meshes as reinforcement materials for sustained local drug delivery against colorectal cancer cells.

Poly-amido-saccharides: synthesis via anionic polymerization of a β-lactam sugar monomer.

Biologically responsive polymeric nanoparticles for drug delivery.

Cytoreductive surgery and intraoperative administration of paclitaxel-loaded expansile nanoparticles delay tumor recurrence in ovarian carcinoma.

Assessment of contrast-enhanced computed tomography for imaging of cartilage during fracture healing.

Contrast-enhanced CT with a high-affinity cationic contrast agent for imaging ex vivo bovine, intact ex vivo rabbit, and in vivo rabbit cartilage.

X-ray-computed tomography contrast agents.

Prevention of nodal metastases in breast cancer following the lymphatic migration of paclitaxel-loaded expansile nanoparticles.

A facile approach to robust superhydrophobic 3D coatings via connective-particle formation using the electrospraying process.

Microscopy and tunable resistive pulse sensing characterization of the swelling of pH-responsive, polymeric expansile nanoparticles.

A large-molecular-weight polyanion, synthesized via ring-opening metathesis polymerization, as a lubricant for human articular cartilage.

Triggered drug release from superhydrophobic meshes using high-intensity focused ultrasound.

Synthesis of atactic and isotactic poly(1,2-glycerol carbonate)s: degradable polymers for biomedical and pharmaceutical applications.

In vitro activity of Paclitaxel-loaded polymeric expansile nanoparticles in breast cancer cells.

Contrast enhanced CT attenuation correlates with the GAG content of bovine meniscus.

A nanopore-nanofiber mesh biosensor to control DNA translocation.

A dendritic thioester hydrogel based on thiol-thioester exchange as a dissolvable sealant system for wound closure.

Embedded multicellular spheroids as a biomimetic 3D cancer model for evaluating drug and drug-device combinations.

Synthesis of Bioinspired Carbohydrate Amphiphiles that Promote and Inhibit Biofilms.

Lipid-mediated DNA and siRNA Transfection Efficiency Depends on Peptide Headgroup.

From Brittle to Pliant Viscoelastic Materials with Solid State Linear Polyphosphonium - Carboxylate Assemblies.

Synthetic Enantiopure Carbohydrate Polymers that are Highly Soluble in Water and Noncytotoxic.

Synthesis of Hydrophobic Carbohydrate Polymers and Their Formation of Thermotropic Liquid Crystalline Phases.

Imparting superhydrophobicity to biodegradable poly(lactide-co-glycolide) electrospun meshes.

Carboxylated glucuronic poly-amido-saccharides as protein stabilizing agents.

Effect of mechanical convection on the partitioning of an anionic iodinated contrast agent in intact patellar cartilage.

Tantalum oxide nanoparticles for the imaging of articular cartilage using X-ray computed tomography: visualization of ex vivo/in vivo murine tibia and ex vivo human index finger cartilage.

The effects of counterion composition on the rheological and conductive properties of mono- and diphosphonium ionic liquids.

Recent advances in glycerol polymers: chemistry and biomedical applications.

A Mechanistic Study of Wetting Superhydrophobic Porous 3D Meshes.

The self-assembly of anticancer camptothecin-dipeptide nanotubes: a minimalistic and high drug loading approach to increased efficacy.

Paclitaxel-loaded expansile nanoparticles enhance chemotherapeutic drug delivery in mesothelioma 3-dimensional multicellular spheroids.

The efficacy of a lysine-based dendritic hydrogel does not differ from those of commercially available tissue sealants and adhesives: an ex vivo study.

A cationic gadolinium contrast agent for magnetic resonance imaging of cartilage.

Synthesis and Characterization of Hybrid Polymer/Lipid Expansile Nanoparticles: Imparting Surface Functionality for Targeting and Stability.

Polymer film-nanoparticle composites as new multimodality, non-migrating breast biopsy markers.

Surface Tension Triggered Wetting and Point of Care Sensor Design.

Layered superhydrophobic meshes for controlled drug release.

Synthesis and Characterization of Poly(glyceric Acid Carbonate): A Degradable Analogue of Poly(acrylic Acid).

Prevention of lung cancer recurrence using cisplatin-loaded superhydrophobic nanofiber meshes.

Functionalized Nanofiber Meshes Enhance Immunosorbent Assays.

Contrast-enhanced CT using a cationic contrast agent enables non-destructive assessment of the biochemical and biomechanical properties of mouse tibial plateau cartilage.

Two-Step Delivery: Exploiting the Partition Coefficient Concept to Increase Intratumoral Paclitaxel Concentrations In vivo Using Responsive Nanoparticles.

Stretch-Induced Drug Delivery from Superhydrophobic Polymer Composites: Use of Crack Propagation Failure Modes for Controlling Release Rates.

Synthetic Biomaterials from Metabolically Derived Synthons.

Nanotechnology applications in thoracic surgery.

Stimuli responsive charge-switchable lipids: Capture and release of nucleic acids.

A Tissue-Penetrating Double Network Restores the Mechanical Properties of Degenerated Articular Cartilage.

Recent Advances in Dendritic Macromonomers for Hydrogel Formation and Their Medical Applications.

BMPR1A antagonist differentially affects cartilage and bone formation during fracture healing.

Self-assembly of a 5-fluorouracil-dipeptide hydrogel.

Evaluation of expansile nanoparticle tumor localization and efficacy in a cancer stem cell-derived model of pancreatic peritoneal carcinomatosis.

From Diagnosis to Treatment: Clinical Applications of Nanotechnology in Thoracic Surgery.

Combined Molecular Dynamics Simulations and Experimental Studies of the Structure and Dynamics of Poly-Amido-Saccharides.

Cationic Contrast Agent Diffusion Differs Between Cartilage and Meniscus.

Ionic Liquid-Organic Carbonate Electrolyte Blends To Stabilize Silicon Electrodes for Extending Lithium Ion Battery Operability to 100 °C.

Contrast-enhanced CT imaging as a non-destructive tool for ex vivo examination of the biochemical content and structure of the human meniscus.

Nanoparticle tumor localization, disruption of autophagosomal trafficking, and prolonged drug delivery improve survival in peritoneal mesothelioma.

Lysosome acidification by photoactivated nanoparticles restores autophagy under lipotoxicity.

On-Demand Dissolution of a Dendritic Hydrogel-based Dressing for Second-Degree Burn Wounds through Thiol-Thioester Exchange Reaction.

Superhydrophobic materials for biomedical applications.

High temperature electrical energy storage: advances, challenges, and frontiers.

Mechanoresponsive materials for drug delivery: Harnessing forces for controlled release.