Department of Genetics
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One for all and all for one: thymic epithelial stem cells and regeneration.
Trends in immunology Aug, 2002 | Pubmed ID: 12133801
Stage-specific changes in fetal thymocyte proliferation during the CD4-8- to CD4+8+ transition in wild type, Rag1-/-, and Hoxa3,Pax1 mutant mice.
BMC immunology Sep, 2002 | Pubmed ID: 12241558
A developmental look at thymus organogenesis: where do the non-hematopoietic cells in the thymus come from?
Current opinion in immunology Apr, 2003 | Pubmed ID: 12633674
New serum-free in vitro culture technique for midgestation mouse embryos.
Genesis (New York, N.Y. : 2000) Mar, 2003 | Pubmed ID: 12640621
A domain of Foxn1 required for crosstalk-dependent thymic epithelial cell differentiation.
Nature immunology Nov, 2003 | Pubmed ID: 14528302
Developing a new paradigm for thymus organogenesis.
Nature reviews. Immunology Apr, 2004 | Pubmed ID: 15057786
Functional evidence for a single endodermal origin for the thymic epithelium.
Nature immunology May, 2004 | Pubmed ID: 15098031
In vivo and in vitro assays of thymic organogenesis.
Methods in molecular medicine , 2005 | Pubmed ID: 15492403
Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs.
Developmental biology Dec, 2004 | Pubmed ID: 15581866
Differential expression of Sonic hedgehog along the anterior-posterior axis regulates patterning of pharyngeal pouch endoderm and pharyngeal endoderm-derived organs.
Developmental biology Feb, 2005 | Pubmed ID: 15680353
Bmp4 and Noggin expression during early thymus and parathyroid organogenesis.
Gene expression patterns : GEP Oct, 2006 | Pubmed ID: 16517216
Lack of Foxp3 function and expression in the thymic epithelium.
The Journal of experimental medicine Mar, 2007 | Pubmed ID: 17353370
Gcm2 is required for the differentiation and survival of parathyroid precursor cells in the parathyroid/thymus primordia.
Developmental biology May, 2007 | Pubmed ID: 17382312
Specific expression of lacZ and cre recombinase in fetal thymic epithelial cells by multiplex gene targeting at the Foxn1 locus.
BMC developmental biology , 2007 | Pubmed ID: 17577402
Atypical memory phenotype T cells with low homeostatic potential and impaired TCR signaling and regulatory T cell function in Foxn1Delta/Delta mutant mice.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2007 | Pubmed ID: 18056358
T cell development from kit-negative progenitors in the Foxn1Delta/Delta mutant thymus.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2008 | Pubmed ID: 18178831
Bmp4 is required for tracheal formation: a novel mouse model for tracheal agenesis.
Developmental biology Oct, 2008 | Pubmed ID: 18692041
Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment.
The Journal of experimental medicine Oct, 2008 | Pubmed ID: 18824585
Foxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive manner.
Blood Jan, 2009 | Pubmed ID: 18978204
Deficient ghrelin receptor-mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity.
The Journal of biological chemistry Mar, 2009 | Pubmed ID: 19054770
Increased thymus- and decreased parathyroid-fated organ domains in Splotch mutant embryos.
Developmental biology Mar, 2009 | Pubmed ID: 19135046
An ancient gene network is co-opted for teeth on old and new jaws.
PLoS biology Feb, 2009 | Pubmed ID: 19215146
An evolutionary perspective on the mechanisms of immunosenescence.
Trends in immunology Jul, 2009 | Pubmed ID: 19541538
Evidence for an early role for BMP4 signaling in thymus and parathyroid morphogenesis.
Developmental biology Mar, 2010 | Pubmed ID: 20043899
Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas.
The Journal of clinical investigation Mar, 2010 | Pubmed ID: 20197623
Mouse and zebrafish Hoxa3 orthologues have nonequivalent in vivo protein function.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2010 | Pubmed ID: 20498049
EphB-ephrin-B2 interactions are required for thymus migration during organogenesis.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2010 | Pubmed ID: 20616004
Transcriptional regulation of thymus organogenesis and thymic epithelial cell differentiation.
Progress in molecular biology and translational science , 2010 | Pubmed ID: 20800818
Impaired thymic selection and abnormal antigen-specific T cell responses in Foxn1(Δ/Δ) mutant mice.
PloS one , 2010 | Pubmed ID: 21079757
Thymus-associated parathyroid hormone has two cellular origins with distinct endocrine and immunological functions.
PLoS genetics , 2010 | Pubmed ID: 21203493
Mechanisms of thymus organogenesis and morphogenesis.
Development (Cambridge, England) Sep, 2011 | Pubmed ID: 21862553
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