Department of Pharmacology and Physiology
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Glucokinase is the likely mediator of glucosensing in both glucose-excited and glucose-inhibited central neurons.
Diabetes Jul, 2002 | Pubmed ID: 12086933
Glucose-sensing neurons: are they physiologically relevant?
Physiology & behavior Jul, 2002 | Pubmed ID: 12117577
CNS sensing and regulation of peripheral glucose levels.
International review of neurobiology , 2002 | Pubmed ID: 12420361
Glucosensing neurons in the ventromedial hypothalamic nucleus (VMN) and hypoglycemia-associated autonomic failure (HAAF).
Diabetes/metabolism research and reviews Sep-Oct, 2003 | Pubmed ID: 12951642
Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus glucosensing neurons.
Diabetes Mar, 2004 | Pubmed ID: 14988237
The role of glucosensing neurons in the detection of hypoglycemia.
Diabetes technology & therapeutics Jun, 2004 | Pubmed ID: 15198847
Neuronal glucosensing: what do we know after 50 years?
Diabetes Oct, 2004 | Pubmed ID: 15448079
Glucokinase is a critical regulator of ventromedial hypothalamic neuronal glucosensing.
Diabetes Feb, 2006 | Pubmed ID: 16443775
Corticotrophin-releasing factor receptors within the ventromedial hypothalamus regulate hypoglycemia-induced hormonal counterregulation.
The Journal of clinical investigation Jun, 2006 | Pubmed ID: 16741581
Recurrent hypoglycemia reduces the glucose sensitivity of glucose-inhibited neurons in the ventromedial hypothalamus nucleus.
American journal of physiology. Regulatory, integrative and comparative physiology Nov, 2006 | Pubmed ID: 16793940
Glucose, insulin, and leptin signaling pathways modulate nitric oxide synthesis in glucose-inhibited neurons in the ventromedial hypothalamus.
American journal of physiology. Regulatory, integrative and comparative physiology Apr, 2007 | Pubmed ID: 17170237
Characterization of glucosensing neuron subpopulations in the arcuate nucleus: integration in neuropeptide Y and pro-opio melanocortin networks?
Diabetes May, 2007 | Pubmed ID: 17261674
Hyperglycemia impairs glucose and insulin regulation of nitric oxide production in glucose-inhibited neurons in the ventromedial hypothalamus.
American journal of physiology. Regulatory, integrative and comparative physiology Aug, 2007 | Pubmed ID: 17537841
Prior hypoglycemia enhances glucose responsiveness in some ventromedial hypothalamic glucosensing neurons.
American journal of physiology. Regulatory, integrative and comparative physiology Mar, 2008 | Pubmed ID: 18094065
Fasting enhances the response of arcuate neuropeptide Y-glucose-inhibited neurons to decreased extracellular glucose.
American journal of physiology. Cell physiology Apr, 2009 | Pubmed ID: 19211911
Insulin blunts the response of glucose-excited neurons in the ventrolateral-ventromedial hypothalamic nucleus to decreased glucose.
American journal of physiology. Endocrinology and metabolism May, 2009 | Pubmed ID: 19223652
AMP-activated protein kinase and nitric oxide regulate the glucose sensitivity of ventromedial hypothalamic glucose-inhibited neurons.
American journal of physiology. Cell physiology Sep, 2009 | Pubmed ID: 19570894
Motor unit number estimate as a predictor of motor dysfunction in an animal model of type 1 diabetes.
American journal of physiology. Endocrinology and metabolism Sep, 2009 | Pubmed ID: 19602580
Ventromedial hypothalamic nitric oxide production is necessary for hypoglycemia detection and counterregulation.
Diabetes Feb, 2010 | Pubmed ID: 19934009
Hypothalamic nitric oxide in hypoglycemia detection and counterregulation: a two-edged sword.
Antioxidants & redox signaling Feb, 2011 | Pubmed ID: 20518706
Brain insulin action regulates hypothalamic glucose sensing and the counterregulatory response to hypoglycemia.
Diabetes Sep, 2010 | Pubmed ID: 20547974
Glucose sensing neurons in the ventromedial hypothalamus.
Sensors (Basel, Switzerland) , 2010 | Pubmed ID: 22022208
Acetylcholinesterase deficiency contributes to neuromuscular junction dysfunction in type 1 diabetic neuropathy.
American journal of physiology. Endocrinology and metabolism Aug, 2012 | Pubmed ID: 22739110
Hypothalamic S-nitrosylation contributes to the counter-regulatory response impairment following recurrent hypoglycemia.
PloS one , 2013 | Pubmed ID: 23894333
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