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Kathleen A. Maguire-Zeiss

Department of Neuroscience

Georgetown University Medical Center

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PUBLICATIONS

Somatic mosaic approaches and the aging brain.

Neurobiology of aging Sep-Oct, 2002 | Pubmed ID: 12392799

Convergent pathobiologic model of Parkinson's disease.

Annals of the New York Academy of Sciences Jun, 2003 | Pubmed ID: 12846984

Safety of viral vectors for neurological gene therapies.

Current opinion in molecular therapeutics Oct, 2004 | Pubmed ID: 15537048

Synuclein, dopamine and oxidative stress: co-conspirators in Parkinson's disease?

Brain research. Molecular brain research Mar, 2005 | Pubmed ID: 15790526

Neuronal precursor-restricted transduction via in utero CNS gene delivery of a novel bipartite HSV amplicon/transposase hybrid vector.

Molecular therapy : the journal of the American Society of Gene Therapy Mar, 2006 | Pubmed ID: 16412694

Identification of human alpha-synuclein specific single chain antibodies.

Biochemical and biophysical research communications Nov, 2006 | Pubmed ID: 16973126

Effects of ex vivo transduction of mesencephalic reaggregates with bcl-2 on grafted dopamine neuron survival.

Brain research Feb, 2007 | Pubmed ID: 17196186

Proteomic analysis of peripheral leukocytes in Alzheimer's disease patients treated with divalproex sodium.

Neurobiology of aging Nov, 2008 | Pubmed ID: 17521776

Synuclein activates microglia in a model of Parkinson's disease.

Neurobiology of aging Nov, 2008 | Pubmed ID: 17537546

Gazing into the future: Parkinson's disease gene therapeutics to modify natural history.

Experimental neurology Jan, 2008 | Pubmed ID: 18035353

alpha-Synuclein: a therapeutic target for Parkinson's disease?

Pharmacological research : the official journal of the Italian Pharmacological Society Nov-Dec, 2008 | Pubmed ID: 18840530

Immune-directed gene therapeutic development for Alzheimer's, prion, and Parkinson's diseases.

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology Sep, 2009 | Pubmed ID: 18931916

Mutant alpha-synuclein overexpression mediates early proinflammatory activity.

Neurotoxicity research Oct, 2009 | Pubmed ID: 19526281

Gene therapy in Parkinson's disease: rationale and current status.

CNS drugs Mar, 2010 | Pubmed ID: 20155994

Future directions for immune modulation in neurodegenerative disorders: focus on Parkinson's disease.

Journal of neural transmission (Vienna, Austria : 1996) Aug, 2010 | Pubmed ID: 20549523

Alpha-synuclein mediates alterations in membrane conductance: a potential role for alpha-synuclein oligomers in cell vulnerability.

The European journal of neuroscience Jul, 2010 | Pubmed ID: 20550572

Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease.

Nature medicine Sep, 2010 | Pubmed ID: 20729864

Dopamine and paraquat enhance α-synuclein-induced alterations in membrane conductance.

Neurotoxicity research Nov, 2011 | Pubmed ID: 21735318

α-Synuclein Alters Toll-Like Receptor Expression.

Frontiers in neuroscience , 2011 | Pubmed ID: 21747756

Misfolded α-synuclein and Toll-like receptors: therapeutic targets for Parkinson's disease.

Parkinsonism & related disorders Jan, 2012 | Pubmed ID: 22166424

Matrix metalloproteinase dependent cleavage of cell adhesion molecules in the pathogenesis of CNS dysfunction with HIV and methamphetamine.

Current HIV research Jul, 2012 | Pubmed ID: 22591362

Microglial activation and antioxidant responses induced by the Parkinson's disease protein α-synuclein.

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology Mar, 2013 | Pubmed ID: 23054368

Parkinson's disease.

Sub-cellular biochemistry , 2012 | Pubmed ID: 23225012

Development of Inducible Leucine-rich Repeat Kinase 2 (LRRK2) Cell Lines for Therapeutics Development in Parkinson's Disease.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics Aug, 2013 | Pubmed ID: 23963789

INSTITUTIONS

Georgetown University Medical Center

JOVE ARTICLES

Isolation of Cortical Microglia with Preserved Immunophenotype and Functionality From Murine Neonates

Stefano G. Daniele¹,

Amanda A. Edwards¹,

Kathleen A. Maguire-Zeiss¹

¹Department of Neuroscience, Georgetown University Medical Center

Immunology and Infection

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Kathleen A. Maguire-Zeiss

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Department of Neuroscience

Georgetown University Medical Center

Isolation of Cortical Microglia with Preserved Immunophenotype and Functionality From Murine Neonates

Department of Neuroscience