Kevin G. Chen

Trafficking and localization of platinum complexes in cisplatin-resistant cell lines monitored by fluorescence-labeled platinum.

Useful tool to generate unidirectional deletion vectors by utilizing the star activity of BamHI in an NcoI-BamHI-XhoI cassette.

Principal expression of two mRNA isoforms (ABCB 5alpha and ABCB 5beta ) of the ATP-binding cassette transporter gene ABCB 5 in melanoma cells and melanocytes.

Genetic and epigenetic modeling of the origins of multidrug-resistant cells in a human sarcoma cell line.

Toward xeno-free culture of human embryonic stem cells.

Sorting of Pmel17 to melanosomes through the plasma membrane by AP1 and AP2: evidence for the polarized nature of melanocytes.

Melanosomal sequestration of cytotoxic drugs contributes to the intractability of malignant melanomas.

Regulation of constitutive and UVR-induced skin pigmentation by melanocortin 1 receptor isoforms.

Sialylated core 1 O-glycans influence the sorting of Pmel17/gp100 and determine its capacity to form fibrils.

Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.

Influence of melanosome dynamics on melanoma drug sensitivity.

Involvement of ABC transporters in melanogenesis and the development of multidrug resistance of melanoma.

Molecular pathways: regulation and therapeutic implications of multidrug resistance.

Regulation and expression of the ATP-binding cassette transporter ABCG2 in human embryonic stem cells.

Non-colony type monolayer culture of human embryonic stem cells.

StemCellDB: The Human Pluripotent Stem Cell Database at the National Institutes of Health.

Human pluripotent stem cell culture: considerations for maintenance, expansion, and therapeutics.

Developmental insights from early mammalian embryos and core signaling pathways that influence human pluripotent cell growth and differentiation.

Directed differentiation of human induced pluripotent stem cells toward bone and cartilage: in vitro versus in vivo assays.