Peter W. Taylor

Methicillin resistance in Staphylococcus aureus: mechanisms and modulation.

Expression, mutagenesis and kinetic analysis of recombinant K1E endosialidase to define the site of proteolytic processing and requirements for catalysis.

New ways to treat bacterial infections.

Structural pharmacogenomics: the answer to antimicrobial drug resistance?

Antimycobacterial activity of indigenous South African plants.

Prevention and cure of systemic Escherichia coli K1 infection by modification of the bacterial phenotype.

Modulation of beta-lactam resistance in Staphylococcus aureus by catechins and gallates.

In vitro activity of extracts and constituents of Pelagonium against rapidly growing mycobacteria.

Anti-Staphylococcus aureus activity and oxacillin resistance modulating capacity of 3-O-acyl-catechins.

Synthesis and antibacterial activity of hydrolytically stable (-)-epicatechin gallate analogues for the modulation of beta-lactam resistance in Staphylococcus aureus.

Treatment of experimental Escherichia coli infection with recombinant bacteriophage-derived capsule depolymerase.

Pyrrolobenzodiazepine dimers: novel sequence-selective, DNA-interactive, cross-linking agents with activity against Gram-positive bacteria.

Towards rational treatment of bacterial infections during extended space travel.

Potentiation of catechin gallate-mediated sensitization of Staphylococcus aureus to oxacillin by nongalloylated catechins.

Single-blind randomized trial of combination antibiotic therapy in rheumatoid arthritis.

Pharmaceutical quality of generic isotretinoin products, compared with Roaccutane.

Epicatechin gallate, a component of green tea, reduces halotolerance in Staphylococcus aureus.

Interactions of pyrrolobenzodiazepine dimers and duplex DNA from methicillin-resistant Staphylococcus aureus.

The beta-lactam-resistance modifier (-)-epicatechin gallate alters the architecture of the cell wall of Staphylococcus aureus.

Differential expression of the polysialyl capsule during blood-to-brain transit of neuropathogenic Escherichia coli K1.

Disruption of D-alanyl esterification of Staphylococcus aureus cell wall teichoic acid by the {beta}-lactam resistance modifier (-)-epicatechin gallate.

Asymmetric total synthesis of B-ring modified (-)-epicatechin gallate analogues and their modulation of beta-lactam resistance in Staphylococcus aureus.

Response of Staphylococcus aureus to subinhibitory concentrations of a sequence-selective, DNA minor groove cross-linking pyrrolobenzodiazepine dimer.

Antimicrobial properties of green tea catechins.

Administration of capsule-selective endosialidase E minimizes upregulation of organ gene expression induced by experimental systemic infection with Escherichia coli K1.

Insertion of epicatechin gallate into the cytoplasmic membrane of methicillin-resistant Staphylococcus aureus disrupts penicillin-binding protein (PBP) 2a-mediated beta-lactam resistance by delocalizing PBP2.

Pharmaceutical quality of nine generic orlistat products compared with Xenical(r).

The minor groove-binding agent ELB-21 forms multiple interstrand and intrastrand covalent cross-links with duplex DNA and displays potent bactericidal activity against methicillin-resistant Staphylococcus aureus.

Anti-staphylococcal activity and β-lactam resistance attenuating capacity of structural analogues of (-)-epicatechin gallate.

Increase in Campylobacter jejuni invasion of intestinal epithelial cells under low-oxygen coculture conditions that reflect the in vivo environment.

Antistaphylococcal activity of DNA-interactive pyrrolobenzodiazepine (PBD) dimers and PBD-biaryl conjugates.

Symmetric bis-benzimidazoles are potent anti-staphylococcal agents with dual inhibitory mechanisms against DNA gyrase.

Biopharmaceutical challenges of therapeutics in space: formulation and packaging considerations.

Transcriptome analysis of responses to rhodomyrtone in methicillin-resistant Staphylococcus aureus.

Poly-γ-(D)-glutamic acid capsule interferes with lytic infection of Bacillus anthracis by B. anthracis-specific bacteriophages.

Draft Genome Sequences of Pseudomonas fluorescens BS2 and Pusillimonas noertemannii BS8, Soil Bacteria That Cooperate To Degrade the Poly-γ-d-Glutamic Acid Anthrax Capsule.

Alternative natural sources for a new generation of antibacterial agents.

Altered innate defenses in the neonatal gastrointestinal tract in response to colonization by neuropathogenic Escherichia coli.

Antibacterial activity of head-to-head bis-benzimidazoles.

A poly-γ-(D)-glutamic acid depolymerase that degrades the protective capsule of Bacillus anthracis.

Staphylococcal phenotypes induced by naturally occurring and synthetic membrane-interactive polyphenolic β-lactam resistance modifiers.

Improved synthesis of structural analogues of (-)-epicatechin gallate for modulation of staphylococcal β-lactam resistance.

Surfactant-free purification of membrane protein complexes from bacteria: application to the staphylococcal penicillin-binding protein complex PBP2/PBP2a.