Andreas Gnirke

Assessing the impact of comparative genomic sequence data on the functional annotation of the Drosophila genome.

DNA sequence and analysis of human chromosome 18.

Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis.

Insights from the genome of the biotrophic fungal plant pathogen Ustilago maydis.

Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites.

The genome of the model beetle and pest Tribolium castaneum.

Genome-scale DNA methylation maps of pluripotent and differentiated cells.

The maternal-effect, selfish genetic element Medea is associated with a composite Tc1 transposon.

Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing.

Ab initio construction of a eukaryotic transcriptome by massively parallel mRNA sequencing.

High-throughput bisulfite sequencing in mammalian genomes.

ALLPATHS 2: small genomes assembled accurately and with high continuity from short paired reads.

Comprehensive mapping of long-range interactions reveals folding principles of the human genome.

Targeted next-generation sequencing of a cancer transcriptome enhances detection of sequence variants and novel fusion transcripts.

ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth.

Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution.

Integrative analysis of the melanoma transcriptome.

Ab initio reconstruction of cell type-specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs.

Targeted exon sequencing by in-solution hybrid selection.

Comprehensive comparative analysis of strand-specific RNA sequencing methods.

Strand-specific RNA sequencing reveals extensive regulated long antisense transcripts that are conserved across yeast species.

Quantitative comparison of genome-wide DNA methylation mapping technologies.

Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications.

High-quality draft assemblies of mammalian genomes from massively parallel sequence data.

Reprogramming factor expression initiates widespread targeted chromatin remodeling.

Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines.

Analyzing and minimizing PCR amplification bias in Illumina sequencing libraries.

Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling.

Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cells.

Full-length transcriptome assembly from RNA-Seq data without a reference genome.

Hybrid selection for sequencing pathogen genomes from clinical samples.

Genomic distribution and inter-sample variation of non-CpG methylation across human cell types.