Robert Damoiseaux

California NanoSystems Institute, University of California, Los Angeles

Affiliated withUniversity of California, Los Angeles Forcyte Biotechnologies University of California Los Angeles

Research Area

Developmental BiologyBioengineering

Biography

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JoVE Journal Publications

Article Total : 3	Year
Publication title	2015
Publication title	2022
Publication title	2022

Other Publications

Article	Year
Towards the generation of artificial O6-alkylguanine-DNA alkyltransferases: in vitro selection of antibodies with reactive cysteine residues. Chembiochem : a European journal of chemical biology\| PubMed ID: 12325014	2002
SRC family kinases: potential targets for the treatment of human cancer and leukemia. Current pharmaceutical design\| PubMed ID: 14529415	2003
PNA-encoded protease substrate microarrays. Chemistry & biology\| PubMed ID: 15489162	2004
Cell-based chemical genetic screen identifies damnacanthal as an inhibitor of HIV-1 Vpr induced cell death. Biochemical and biophysical research communications\| PubMed ID: 16904642	2006
Mycophenolic acid is a potent inhibitor of angiogenesis. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 16990565	2006
Amiodarone and bepridil inhibit anthrax toxin entry into host cells. Antimicrobial agents and chemotherapy\| PubMed ID: 17485504	2007
The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARgamma expression. Cell metabolism\| PubMed ID: 17488638	2007
Regulation of Kaposi's sarcoma-associated herpesvirus reactivation by dopamine receptor-mediated signaling pathways. Journal of acquired immune deficiency syndromes (1999)\| PubMed ID: 18645521	2008
A high-throughput screening strategy identifies cardiotonic steroids as alternative splicing modulators. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18678901	2008
Ion channel and toxin measurement using a high throughput lipid membrane platform. Biosensors & bioelectronics\| PubMed ID: 18849158	2009
Integrated chemical genomics reveals modifiers of survival in human embryonic stem cells. Stem cells (Dayton, Ohio)\| PubMed ID: 19074420	2009
Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 19762431	2010
Nonaminoglycoside compounds induce readthrough of nonsense mutations. The Journal of experimental medicine\| PubMed ID: 19770270	2009
Discovery and structure-activity relationship analysis of Staphylococcus aureus sortase A inhibitors. Bioorganic & medicinal chemistry\| PubMed ID: 19781950	2009
High-throughput screening identifies two classes of antibiotics as radioprotectors: tetracyclines and fluoroquinolones. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19920105	2009
Use of a rapid cytotoxicity screening approach to engineer a safer zinc oxide nanoparticle through iron doping. ACS nano\| PubMed ID: 20043640	2010
Integrated pathways for neutrophil recruitment and inflammation in leprosy. The Journal of infectious diseases\| PubMed ID: 20070238	2010
A broad-spectrum antiviral targeting entry of enveloped viruses. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20133606	2010
Substrate specificity of the TIM22 mitochondrial import pathway revealed with small molecule inhibitor of protein translocation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20457929	2010
Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase. Nature biotechnology\| PubMed ID: 20581845	2010
High-content screening for biofilm assays. Journal of biomolecular screening\| PubMed ID: 20639506	2010
High-throughput screening of silver nanoparticle stability and bacterial inactivation in aquatic media: influence of specific ions. Environmental science & technology\| PubMed ID: 20873875	2010
Microfluidic image cytometry. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21104065	2011
Stability, bioavailability, and bacterial toxicity of ZnO and iron-doped ZnO nanoparticles in aquatic media. Environmental science & technology\| PubMed ID: 21133426	2011
Metabolic imaging allows early prediction of response to vandetanib. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 21233183	2011
Self-organizing map analysis of toxicity-related cell signaling pathways for metal and metal oxide nanoparticles. Environmental science & technology\| PubMed ID: 21250674	2011
No time to lose--high throughput screening to assess nanomaterial safety. Nanoscale\| PubMed ID: 21301704	2011
Use of a high-throughput screening approach coupled with in vivo zebrafish embryo screening to develop hazard ranking for engineered nanomaterials. ACS nano\| PubMed ID: 21323332	2011
Differential expression of syndecan-1 mediates cationic nanoparticle toxicity in undifferentiated versus differentiated normal human bronchial epithelial cells. ACS nano\| PubMed ID: 21366263	2011
High throughput screening of small molecule libraries for modifiers of radiation responses. International journal of radiation biology\| PubMed ID: 21401317	2011
Seeing the light: luminescent reporter gene assays. Combinatorial chemistry & high throughput screening\| PubMed ID: 21564017	2011
High content screening in zebrafish speeds up hazard ranking of transition metal oxide nanoparticles. ACS nano\| PubMed ID: 21851096	2011
A molecular screening approach to identify and characterize inhibitors of glioblastoma stem cells. Molecular cancer therapeutics\| PubMed ID: 21859839	2011
Synergistic bactericidal activity of Ag-TiO₂ nanoparticles in both light and dark conditions. Environmental science & technology\| PubMed ID: 21866941	2011
Genome-wide bacterial toxicity screening uncovers the mechanisms of toxicity of a cationic polystyrene nanomaterial. Environmental science & technology\| PubMed ID: 22148163	2012
Combination of Rad001 (everolimus) and propachlor synergistically induces apoptosis through enhanced autophagy in prostate cancer cells. Molecular cancer therapeutics\| PubMed ID: 22491797	2012
Use of metal oxide nanoparticle band gap to develop a predictive paradigm for oxidative stress and acute pulmonary inflammation. ACS nano\| PubMed ID: 22502734	2012
Automated phenotype recognition for zebrafish embryo based in vivo high throughput toxicity screening of engineered nano-materials. PloS one\| PubMed ID: 22506062	2012
Quantitative detection of PfHRP2 in saliva of malaria patients in the Philippines. Malaria journal\| PubMed ID: 22631858	2012
Fluoxetine is a potent inhibitor of coxsackievirus replication. Antimicrobial agents and chemotherapy\| PubMed ID: 22751539	2012
Inhibition of aminoacylase 3 protects rat brain cortex neuronal cells from the toxicity of 4-hydroxy-2-nonenal mercapturate and 4-hydroxy-2-nonenal. Toxicology and applied pharmacology\| PubMed ID: 22819785	2012
Size of TiO(2) nanoparticles influences their phototoxicity: an in vitro investigation. Archives of toxicology\| PubMed ID: 22885792	2013
Size influences the cytotoxicity of poly (lactic-co-glycolic acid) (PLGA) and titanium dioxide (TiO(2)) nanoparticles. Archives of toxicology\| PubMed ID: 22983807	2013
Genome-wide assessment in Escherichia coli reveals time-dependent nanotoxicity paradigms. ACS nano\| PubMed ID: 23039911	2012
Zebrafish high-throughput screening to study the impact of dissolvable metal oxide nanoparticles on the hatching enzyme, ZHE1. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 23180726	2013
Dantrolene enhances antisense-mediated exon skipping in human and mouse models of Duchenne muscular dystrophy. Science translational medicine\| PubMed ID: 23241744	2012
High-throughput screening of small molecules identifies hepcidin antagonists. Molecular pharmacology\| PubMed ID: 23292796	2013
A small molecule inhibitor of redox-regulated protein translocation into mitochondria. Developmental cell\| PubMed ID: 23597483	2013
A broadly applicable high-throughput screening strategy identifies new regulators of Dlg4 (Psd-95) alternative splicing. Genome research\| PubMed ID: 23636947	2013
A new series of small molecular weight compounds induce read through of all three types of nonsense mutations in the ATM gene. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 23774824	2013
Development of new deoxycytidine kinase inhibitors and noninvasive in vivo evaluation using positron emission tomography. Journal of medicinal chemistry\| PubMed ID: 23947754	2013
Genome-wide RNAi high-throughput screen identifies proteins necessary for the AHR-dependent induction of CYP1A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 23997114	2013
Selective inhibitor of endosomal trafficking pathways exploited by multiple toxins and viruses. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24191014	2013
Calcium signaling via Orai1 is essential for induction of the nuclear orphan receptor pathway to drive Th17 differentiation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24307733	2014
UCLA's Molecular Screening Shared Resource: enhancing small molecule discovery with functional genomics and new technology. Combinatorial chemistry & high throughput screening\| PubMed ID: 24661210	2014
Cytolethal distending toxins require components of the ER-associated degradation pathway for host cell entry. PLoS pathogens\| PubMed ID: 25078082	2014
Identification of small molecules that disrupt signaling between ABL and its positive regulator RIN1. PloS one\| PubMed ID: 25811598	2015
Glucocorticoids suppress renal cell carcinoma progression by enhancing Na,K-ATPase beta-1 subunit expression. PloS one\| PubMed ID: 25836370	2015
Adaptation of a Genetic Screen Reveals an Inhibitor for Mitochondrial Protein Import Component Tim44. The Journal of biological chemistry\| PubMed ID: 28167535	2017
Direct quantification of gamma H2AX by cell-based high throughput screening for evaluation of genotoxicity of pesticides in a human thyroid cell lines. Environmental and molecular mutagenesis\| PubMed ID: 28640454	2017
Gα facilitates shortening in human airway smooth muscle by modulating phosphoinositide 3-kinase-mediated activation in a RhoA-dependent manner. British journal of pharmacology\| PubMed ID: 28921504	2017
High-Throughput Screening of a Luciferase Reporter of Gene Silencing on the Inactive X Chromosome. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29671264	2018
Making It All Work: Functional Genomics and Reporter Gene Assays. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29671265	2018
Reporter Gene Assays Using Transfectable Functional Genomics Libraries. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29671266	2018
Reporter Gene Assays Using Viral Functional Genomics Libraries. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29671267	2018
A scalable filtration method for high throughput screening based on cell deformability. Lab on a chip\| PubMed ID: 30566156	2019
Metabolic Modifier Screen Reveals Secondary Targets of Protein Kinase Inhibitors within Nucleotide Metabolism. Cell chemical biology\| PubMed ID: 31734178	2020
Development of a high-throughput screen to identify small molecule enhancers of sarcospan for the treatment of Duchenne muscular dystrophy. Skeletal muscle\| PubMed ID: 31831063	2019
Repurposing metformin, simvastatin and digoxin as a combination for targeted therapy for pancreatic ductal adenocarcinoma. Cancer letters\| PubMed ID: 32829010	2020
High-throughput screening identifies modulators of sarcospan that stabilize muscle cells and exhibit activity in the mouse model of Duchenne muscular dystrophy. Skeletal muscle\| PubMed ID: 32948250	2020
Uncoupling interferon signaling and antigen presentation to overcome immunotherapy resistance due to JAK1 loss in melanoma. Science translational medicine\| PubMed ID: 33055240	2020
Commercial immunoglobulin products contain cross-reactive but not neutralizing antibodies against SARS-CoV-2. The Journal of allergy and clinical immunology\| PubMed ID: 33358557	2021
PSA-Targeted Alpha-, Beta-, and Positron-Emitting Immunotheranostics in Murine Prostate Cancer Models and Nonhuman Primates. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 33441295	2021
Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication. Cell reports\| PubMed ID: 33784499	2021
Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells. Cell reports\| PubMed ID: 35021095	2022