Elizabeth M. Topp

Reaction of a peptide with polyvinylpyrrolidone in the solid state.

Gastric function in the elderly: effects on absorption of ketoconazole.

Racemization of an asparagine residue during peptide deamidation.

Polyvinylpyrrolidone-drug conjugate: synthesis and release mechanism.

Solid-state NMR studies of pharmaceutical solids in polymer matrices.

Release from polymeric prodrugs: linkages and their degradation.

Applications of model beta-hairpin peptides.

Effects of acidic N + 1 residues on asparagine deamidation rates in solution and in the solid state.

Effects of sucrose and mannitol on asparagine deamidation rates of model peptides in solution and in the solid state.

Deamidation of model beta-turn cyclic peptides in the solid state.

Effect of N-1 and N-2 residues on peptide deamidation rate in solution and solid state.

Trehalose and calcium exert site-specific effects on calmodulin conformation in amorphous solids.

Characterizing protein structure in amorphous solids using hydrogen/deuterium exchange with mass spectrometry.

Effects of excipients on protein conformation in lyophilized solids by hydrogen/deuterium exchange mass spectrometry.

Reversibility and regioselectivity in thiol/disulfide interchange of tocinoic acid with glutathione in lyophilized solids.

Comparison of LC and LC/MS methods for quantifying N-glycosylation in recombinant IgGs.

Protein conformation in amorphous solids by FTIR and by hydrogen/deuterium exchange with mass spectrometry.

Recent U.S. patents on protein drug formulation: 2000-2007.

Dynamic mechanical analysis and esterase degradation of dentin adhesives containing a branched methacrylate.

Effect of protein structure on deamidation rate in the Fc fragment of an IgG1 monoclonal antibody.

Enzyme-catalyzed hydrolysis of dentin adhesives containing a new urethane-based trimethacrylate monomer.

Water sorption and dynamic mechanical properties of dentin adhesives with a urethane-based multifunctional methacrylate monomer.

Immune response to controlled release of immunomodulating peptides in a murine experimental autoimmune encephalomyelitis (EAE) model.

Effect of photoinitiator system and water content on dynamic mechanical properties of a light-cured bisGMA/HEMA dental resin.

Adhesive/Dentin interface: the weak link in the composite restoration.

Thiol-disulfide interchange in the tocinoic acid/glutathione system during freezing and drying.

Protein G, protein A and protein A-derived peptides inhibit the agitation induced aggregation of IgG.

Localized hydration in lyophilized myoglobin by hydrogen-deuterium exchange mass spectrometry. 1. Exchange mapping.

Localized hydration in lyophilized myoglobin by hydrogen-deuterium exchange mass spectrometry. 2. Exchange kinetics.

Preparation and Properties of Novel Dentin Adhesives with Esterase Resistance.

Microarrays and microneedle arrays for delivery of peptides, proteins, vaccines and other applications.

Photolytic labeling to probe molecular interactions in lyophilized powders.

Protein aggregation and lyophilization: Protein structural descriptors as predictors of aggregation propensity.

Thiol-disulfide exchange in peptides derived from human growth hormone.

Commentary: current perspectives on the aggregation of protein drugs.

Analyzing subvisible particles in protein drug products: a comparison of dynamic light scattering (DLS) and resonant mass measurement (RMM).

Predicting protein aggregation during storage in lyophilized solids using solid state amide hydrogen/deuterium exchange with mass spectrometric analysis (ssHDX-MS).

Thiol-disulfide exchange in peptides derived from human growth hormone during lyophilization and storage in the solid state.

Structural transitions and interactions in the early stages of human glucagon amyloid fibrillation.