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Division of Cardiovascular Medicine,
Department of Medicine,
Division of Cardiovascular Medicine, Department of Medicine
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Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice.
Cell Oct, 2004 | Pubmed ID: 15454086
Defects in energy homeostasis in Leigh syndrome French Canadian variant through PGC-1alpha/LRP130 complex.
Genes & development Nov, 2006 | Pubmed ID: 17050673
Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex.
Genes & development May, 2008 | Pubmed ID: 18483224
Modulation of PGC-1 coactivator pathways in brown fat differentiation through LRP130.
The Journal of biological chemistry Nov, 2008 | Pubmed ID: 18728005
Sensitivity of lipid metabolism and insulin signaling to genetic alterations in hepatic peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression.
Diabetes Jul, 2009 | Pubmed ID: 19366863
Synergistic steatohepatitis by moderate obesity and alcohol in mice despite increased adiponectin and p-AMPK.
Journal of hepatology Sep, 2011 | Pubmed ID: 21256905
Epigenetic control of angiogenesis via DNA methylation.
Circulation Jun, 2011 | Pubmed ID: 21670233
LRP130 protein remodels mitochondria and stimulates fatty acid oxidation.
The Journal of biological chemistry Dec, 2011 | Pubmed ID: 21971050
TRPM2 Ca2+ channel regulates energy balance and glucose metabolism.
American journal of physiology. Endocrinology and metabolism Apr, 2012 | Pubmed ID: 22275755
The histone demethylase Jhdm1a regulates hepatic gluconeogenesis.
PLoS genetics , 2012 | Pubmed ID: 22719268
Interplay of mitochondrial biogenesis and oxidative stress in heart failure.
Circulation May, 2013 | Pubmed ID: 23589023
Uncoupling protein 2 impacts endothelial phenotype via p53-mediated control of mitochondrial dynamics.
Circulation research Sep, 2013 | Pubmed ID: 23819990
KLF15 is a molecular link between endoplasmic reticulum stress and insulin resistance.
PloS one , 2013 | Pubmed ID: 24167585
Nutrient sensing by the mitochondrial transcription machinery dictates oxidative phosphorylation.
The Journal of clinical investigation Feb, 2014 | Pubmed ID: 24430182
OXPHOS-Mediated Induction of NAD+ Promotes Complete Oxidation of Fatty Acids and Interdicts Non-Alcoholic Fatty Liver Disease.
PloS one , 2015 | Pubmed ID: 25933096
Role of Energy Metabolism in the Brown Fat Gene Program.
Frontiers in endocrinology , 2015 | Pubmed ID: 26175716
University of Massachusetts Medical School
Thomas E. Akie1,
Marcus P. Cooper1
1Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School
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