Helmut Butzkueven

Genetic dissection of the human leukocyte antigen region by use of haplotypes of Tasmanians with multiple sclerosis.

LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival.

Prospects for stem cell transplantation in multiple sclerosis.

Schwann cell apoptosis in the postnatal axotomized sciatic nerve is mediated via NGF through the low-affinity neurotrophin receptor.

Extended haplotype analysis in the HLA complex reveals an increased frequency of the HFE-C282Y mutation in individuals with multiple sclerosis.

Neuroglial responses to CNS injury: prospects for novel therapeutics.

Multiple sclerosis: a haplotype association study.

On the utility of data from the International HapMap Project for Australian association studies.

Endogenous leukemia inhibitory factor production limits autoimmune demyelination and oligodendrocyte loss.

Suppressor of cytokine signaling 3 limits protection of leukemia inhibitory factor receptor signaling against central demyelination.

Dopamine agonist-induced pathological gambling in restless legs syndrome due to multiple sclerosis.

Analysis of extended HLA haplotypes in multiple sclerosis and narcolepsy families confirms a predisposing effect for the class I region in Tasmanian MS patients.

MR diffusion changes correlate with ultra-structurally defined axonal degeneration in murine optic nerve.

Prolonged interval between sentinel pseudotumoral demyelination and development of primary CNS lymphoma.

Leukemia inhibitory factor signaling modulates both central nervous system demyelination and myelin repair.

Gas6 deficiency increases oligodendrocyte loss and microglial activation in response to cuprizone-induced demyelination.

Validation of a novel biomarker for acute axonal injury in experimental autoimmune encephalomyelitis.

Optic nerve diffusion changes and atrophy jointly predict visual dysfunction after optic neuritis.

Fine mapping of multiple sclerosis susceptibility genes provides evidence of allelic heterogeneity at the IL2RA locus.

A role for galanin in human and experimental inflammatory demyelination.

Neuroprotection in multiple sclerosis: a therapeutic challenge for the next decade.

Multiple sclerosis susceptibility-associated SNPs do not influence disease severity measures in a cohort of Australian MS patients.

Common variation in the MOG gene influences transcript splicing in humans.

A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis.

Galanin in glia: expression and potential roles in the CNS.

Brain plasticity in relapsing-remitting multiple sclerosis: evidence from resting-state fMRI.

Vaginally administered PEGylated LIF antagonist blocked embryo implantation and eliminated non-target effects on bone in mice.

Clinical isolated syndrome: a 3-year follow-up study in China.

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

Diffusion tensor imaging of the optic radiations after optic neuritis.

Neurofilament proteins as body fluid biomarkers of neurodegeneration in multiple sclerosis.

A tract-based diffusion study of cerebral white matter in neuromyelitis optica reveals widespread pathological alterations.

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.

Neurodegeneration in MS and NMO: The Eye and the Blood.

The Kurtzke EDSS rank stability increases 4 years after the onset of multiple sclerosis: results from the MSBase Registry.

Diffusion tensor imaging correlates of visual impairment in multiple sclerosis and chronic optic neuritis.

Increasing age at disability milestones among MS patients in the MSBase Registry.

A double-blind, randomized, controlled study of botulinum toxin type A in MS-related tremor.

Country, sex, EDSS change and therapy choice independently predict treatment discontinuation in multiple sclerosis and clinically isolated syndrome.

Baseline brain activity changes in patients with clinically isolated syndrome revealed by resting-state functional MRI.

Leukemia inhibitory factor protects axons in experimental autoimmune encephalomyelitis via an oligodendrocyte-independent mechanism.

Geographical variations in sex ratio trends over time in multiple sclerosis.

Altered topological organization of white matter structural networks in patients with neuromyelitis optica.

Commentary on "Possible induction of acute disseminated encephalomyelitis (ADEM)-like demyelinating illness by intrathecal mesenchymal stem cell injection".

What do effective treatments for multiple sclerosis tell us about the molecular mechanisms involved in pathogenesis?

Microstructural abnormalities in the trigeminal nerves of patients with trigeminal neuralgia revealed by multiple diffusion metrics.

Optic nerve magnetisation transfer ratio after acute optic neuritis predicts axonal and visual outcomes.

EphA4 receptor tyrosine kinase is a modulator of onset and disease severity of experimental autoimmune encephalomyelitis (EAE).

The Australian Multiple Sclerosis (MS) immunotherapy study: a prospective, multicentre study of drug utilisation using the MSBase platform.

Persistence on therapy and propensity matched outcome comparison of two subcutaneous interferon Beta 1a dosages for multiple sclerosis.

Anti-aquaporin-4 antibody positivity in neuromyelitis optica is associated with lesion activity.

Responsiveness of the Multiple Sclerosis International Quality of Life questionnaire to disability change: a longitudinal study.

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.

Predictors and dynamics of postpartum relapses in women with multiple sclerosis.

Sex as a determinant of relapse incidence and progressive course of multiple sclerosis.

Endogenously regulated Dab2 worsens inflammatory injury in experimental autoimmune encephalomyelitis.

Optic nerve diffusion tensor imaging after acute optic neuritis predicts axonal and visual outcomes.

Efficacy and safety of natalizumab in multiple sclerosis: interim observational programme results.

Fingolimod after natalizumab and the risk of short-term relapse.

Ceruloplasmin gene-deficient mice with experimental autoimmune encephalomyelitis show attenuated early disease evolution.

Risk of relapse phenotype recurrence in multiple sclerosis.

Cortical thinning correlates with cognitive change in multiple sclerosis but not in neuromyelitis optica.

Therapeutic approaches to disease modifying therapy for multiple sclerosis in adults: an Australian and New Zealand perspective: part 2 new and emerging therapies and their efficacy. MS Neurology Group of the Australian and New Zealand Association of Neurologists.

Therapeutic approaches to disease modifying therapy for multiple sclerosis in adults: an Australian and New Zealand perspective: part 1 historical and established therapies. MS Neurology Group of the Australian and New Zealand Association of Neurologists.

Therapeutic approaches to disease modifying therapy for multiple sclerosis in adults: an Australian and New Zealand perspective: part 3 treatment practicalities and recommendations. MS Neurology Group of the Australian and New Zealand Association of Neurologists.

Seasonal variation of relapse rate in multiple sclerosis is latitude dependent.

Axonally derived matrilin-2 induces proinflammatory responses that exacerbate autoimmune neuroinflammation.

Continuing fingolimod after development of macular edema: A case report.

Comparative effectiveness of glatiramer acetate and interferon beta formulations in relapsing-remitting multiple sclerosis.

Switch to natalizumab versus fingolimod in active relapsing-remitting multiple sclerosis.

Altered thalamic functional connectivity in multiple sclerosis.

Galanin is an autocrine myelin and oligodendrocyte trophic signal induced by leukemia inhibitory factor.

Comparison of switch to fingolimod or interferon beta/glatiramer acetate in active multiple sclerosis.

Comparative efficacy of switching to natalizumab in active multiple sclerosis.

Predictors of disability worsening in clinically isolated syndrome.

Parallel changes in structural and functional measures of optic nerve myelination after optic neuritis.

Switching from natalizumab to fingolimod: A randomized, placebo-controlled study in RRMS.

Male Sex Is Independently Associated with Faster Disability Accumulation in Relapse-Onset MS but Not in Primary Progressive MS.

The MS Risk Allele of CD40 Is Associated with Reduced Cell-Membrane Bound Expression in Antigen Presenting Cells: Implications for Gene Function.

A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis.

The effect of oral immunomodulatory therapy on treatment uptake and persistence in multiple sclerosis.

A new era in the treatment of multiple sclerosis.

Defining reliable disability outcomes in multiple sclerosis.