Philip D. Compton

Methods for analyzing peptides and proteins on a chromatographic timescale by electron-transfer dissociation mass spectrometry.

Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates cytokinesis.

On the scalability and requirements of whole protein mass spectrometry.

Mapping intact protein isoforms in discovery mode using top-down proteomics.

Optimization of electron transfer dissociation via informed selection of reagents and operating parameters.

Evaluation of the compact high-field orbitrap for top-down proteomics of human cells.

Spinning up mass spectrometry for whole protein complexes.

Top down proteomics of human membrane proteins from enriched mitochondrial fractions.

Front-end electron transfer dissociation: a new ionization source.

From protein complexes to subunit backbone fragments: a multi-stage approach to native mass spectrometry.

Autopilot: an online data acquisition control system for the enhanced high-throughput characterization of intact proteins.

Optimizing capillary electrophoresis for top-down proteomics of 30-80 kDa proteins.

Fragmentation of integral membrane proteins in the gas phase.

Deep and quantitative top-down proteomics in clinical and translational research.

Native GELFrEE: a new separation technique for biomolecular assemblies.

Online matrix removal platform for coupling gel-based separations to whole protein electrospray ionization mass spectrometry.

Targeted analysis of recombinant NF kappa B (RelA/p65) by denaturing and native top down mass spectrometry.

Unabridged Analysis of Human Histone H3 by Differential Top-Down Mass Spectrometry Reveals Hypermethylated Proteoforms from MMSET/NSD2 Overexpression.

Integrated Bottom-Up and Top-Down Proteomics of Patient-Derived Breast Tumor Xenografts.

Probing Asymmetric Charge Partitioning of Protein Oligomers during Tandem Mass Spectrometry.

Reducing protein oxidation in low-flow electrospray enables deeper investigation of proteoforms by top down proteomics.

An informatic framework for decoding protein complexes by top-down mass spectrometry.