Molecular and Cellular Cognition Lab
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Regional effects of wheel running and environmental enrichment on cell genesis and microglia proliferation in the adult murine neocortex.
Cerebral cortex (New York, N.Y. : 1991) Aug, 2003 | Pubmed ID: 12853371
Trafficking in emotions.
Nature neuroscience May, 2005 | Pubmed ID: 15856058
Physical exercise prevents age-related decline in precursor cell activity in the mouse dentate gyrus.
Neurobiology of aging Oct, 2006 | Pubmed ID: 16271278
Variability of doublecortin-associated dendrite maturation in adult hippocampal neurogenesis is independent of the regulation of precursor cell proliferation.
BMC neuroscience , 2006 | Pubmed ID: 17105671
Neurogenesis in the adult hippocampus.
Cell and tissue research Jan, 2008 | Pubmed ID: 17938969
Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2007 | Pubmed ID: 17984054
Interactions between the NR2B receptor and CaMKII modulate synaptic plasticity and spatial learning.
The Journal of neuroscience : the official journal of the Society for Neuroscience Dec, 2007 | Pubmed ID: 18077696
Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis.
Nature medicine Aug, 2008 | Pubmed ID: 18568033
Reversing neurodevelopmental disorders in adults.
Neuron Dec, 2008 | Pubmed ID: 19109903
Genetics and neuropsychiatric disorders: treatment during adulthood.
Nature medicine Aug, 2009 | Pubmed ID: 19661989
Adult reversal of cognitive phenotypes in neurodevelopmental disorders.
Journal of neurodevelopmental disorders Jun, 2009 | Pubmed ID: 19812701
Additive effects of physical exercise and environmental enrichment on adult hippocampal neurogenesis in mice.
Frontiers in neuroscience , 2009 | Pubmed ID: 20582277
Neurofibromin regulates corticostriatal inhibitory networks during working memory performance.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2010 | Pubmed ID: 20624961
Increased levels of anxiety-related behaviors in a Tsc2 dominant negative transgenic mouse model of tuberous sclerosis.
Behavior genetics May, 2011 | Pubmed ID: 20882401
Rapamycin for treating Tuberous sclerosis and Autism spectrum disorders.
Trends in molecular medicine Feb, 2011 | Pubmed ID: 21115397
Why and how physical activity promotes experience-induced brain plasticity.
Frontiers in neuroscience , 2010 | Pubmed ID: 21151782
Enriched environment and physical activity reduce microglia and influence the fate of NG2 cells in the amygdala of adult mice.
Cell and tissue research Jul, 2011 | Pubmed ID: 21688212
From genes to cognition in tuberous sclerosis: implications for mTOR inhibitor-based treatment approaches.
Neuropharmacology May, 2013 | Pubmed ID: 22626986
Adult-onset fluoxetine treatment does not improve behavioral impairments and may have adverse effects on the Ts65Dn mouse model of Down syndrome.
Neural plasticity , 2012 | Pubmed ID: 22848851
mTOR Inhibition ameliorates cognitive and affective deficits caused by Disc1 knockdown in adult-born dentate granule neurons.
Neuron Feb, 2013 | Pubmed ID: 23439118
Rapamycin extends murine lifespan but has limited effects on aging.
The Journal of clinical investigation Aug, 2013 | Pubmed ID: 23863708
Longevity, aging and rapamycin.
Cellular and molecular life sciences : CMLS Nov, 2014 | Pubmed ID: 25015322
The anti-diabetic drug metformin reduces BACE1 protein level by interfering with the MID1 complex.
PloS one , 2014 | Pubmed ID: 25025689
Tsc2 Haploinsufficiency Has Limited Effects on Fetal Brain Cytokine Levels during Gestational Immune Activation.
Autism research and treatment , 2014 | Pubmed ID: 25114803
Bison: bisulfite alignment on nodes of a cluster.
BMC bioinformatics , 2014 | Pubmed ID: 25326660
Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome.
Nature neuroscience Dec, 2014 | Pubmed ID: 25383899
Limited effects of an eIF2αS51A allele on neurological impairments in the 5xFAD mouse model of Alzheimer's disease.
Neural plasticity , 2015 | Pubmed ID: 25883808
Altered theta oscillations and aberrant cortical excitatory activity in the 5XFAD model of Alzheimer's disease.
Neural plasticity , 2015 | Pubmed ID: 25922768
Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies.
Acta neuropathologica Nov, 2015 | Pubmed ID: 26439832
EEG Radiotelemetry in Small Laboratory Rodents: A Powerful State-of-the Art Approach in Neuropsychiatric, Neurodegenerative, and Epilepsy Research.
Neural plasticity , 2016 | Pubmed ID: 26819775
Gender-Specific Hippocampal Dysrhythmia and Aberrant Hippocampal and Cortical Excitability in the APPswePS1dE9 Model of Alzheimer's Disease.
Neural plasticity , 2016 | Pubmed ID: 27840743
Sphingosine 1-phosphate lyase ablation disrupts presynaptic architecture and function via an ubiquitin- proteasome mediated mechanism.
Scientific reports Nov, 2016 | Pubmed ID: 27883090
Motor Cortex Theta and Gamma Architecture in Young Adult APPswePS1dE9 Alzheimer Mice.
PloS one , 2017 | Pubmed ID: 28072877
Environmental Chemicals and Aging.
Current environmental health reports Mar, 2017 | Pubmed ID: 28102525
Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice.
Nature communications Jul, 2017 | Pubmed ID: 28761067
Novel evidence for paternal dietary influences on cognitive and neural functions in offspring mice.
Molecular psychiatry 11, 2018 | Pubmed ID: 29038600
Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice.
Proceedings of the National Academy of Sciences of the United States of America 03, 2018 | Pubmed ID: 29467291
Andreas Lundt1,2,
Julien Soos1,
Christina Henseler1,
Muhammad Imran Arshaad1,
Ralf Müller3,
Dan Ehninger4,
Jürgen Hescheler5,
Agapios Sachinidis5,
Karl Broich6,
Carola Wormuth1,7,
Anna Papazoglou1,
Marco Weiergräber1
1Experimental Neuropsychopharmacology, Federal Institute for Drugs and Medical Devices,
2, KBRwyle GmbH,
3Cognitive Neurophysiology, Department of Psychiatry and Psychotherapy, Faculty of Medicine, University of Cologne,
4Molecular and Cellular Cognition, German Center for Neurodegenerative Diseases (DZNE),
5Institute of Neurophysiology, Faculty of Medicine, University of Cologne,
6, Federal Institute for Drugs and Medical Devices (BfArM),
7, Thescon GmbH
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