Justin Sturge

N-WASP activation by a beta1-integrin-dependent mechanism supports PI3K-independent chemotaxis stimulated by urokinase-type plasminogen activator.

Regulation of breast cancer cell chemotaxis by the phosphoinositide 3-kinase p110delta.

A targeted deletion in the endocytic receptor gene Endo180 results in a defect in collagen uptake.

GPI-anchored uPAR requires Endo180 for rapid directional sensing during chemotaxis.

Endosomes generate localized Rho-ROCK-MLC2-based contractile signals via Endo180 to promote adhesion disassembly.

Mannose receptor regulation of macrophage cell migration.

The collagen receptor Endo180 (CD280) Is expressed on basal-like breast tumor cells and promotes tumor growth in vivo.

Endo180 expression with cofunctional partners MT1-MMP and uPAR-uPA is correlated with prostate cancer progression.

Biological and clinical implications of nicastrin expression in invasive breast cancer.

Bone metastasis in prostate cancer: emerging therapeutic strategies.

TGFβ1-Endo180-dependent collagen deposition is dysregulated at the tumour-stromal interface in bone metastasis.

Fluorescence-based experimental model to evaluate the concomitant effect of drugs on the tumour microenvironment and cancer cells.

Survival Outcome and EMT Suppression Mediated by a Lectin Domain Interaction of Endo180 and CD147.

AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival.

Tumor-associated Endo180 requires stromal-derived LOX to promote metastatic prostate cancer cell migration on human ECM surfaces.

Endo180 at the cutting edge of bone cancer treatment and beyond.