Jaewon Lee

Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease.

Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice.

Phenformin suppresses calcium responses to glutamate and protects hippocampal neurons against excitotoxicity.

Adverse effect of a presenilin-1 mutation in microglia results in enhanced nitric oxide and inflammatory cytokine responses to immune challenge in the brain.

Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice.

Neuroprotective and neurorestorative signal transduction mechanisms in brain aging: modification by genes, diet and behavior.

Seizures and tissue injury induce telomerase in hippocampal microglial cells.

Influence of cytosolic and mitochondrial Ca2+, ATP, mitochondrial membrane potential, and calpain activity on the mechanism of neuron death induced by 3-nitropropionic acid.

Interactive effects of excitotoxic injury and dietary restriction on microgliosis and neurogenesis in the hippocampus of adult mice.

Herp stabilizes neuronal Ca2+ homeostasis and mitochondrial function during endoplasmic reticulum stress.

Aging effect on myeloperoxidase in rat kidney and its modulation by calorie restriction.

SMP30 deficiency causes increased oxidative stress in brain.

Interferon-gamma is up-regulated in the hippocampus in response to intermittent fasting and protects hippocampal neurons against excitotoxicity.

Upregulation of aortic adhesion molecules during aging.

Preliminary X-ray crystallographic analysis of the catalytic domain of prophenoloxidase activating factor-I.

Interferon-gamma promotes differentiation of neural progenitor cells via the JNK pathway.

Role of hypoxia-inducible factor-alpha in hepatitis-B-virus X protein-mediated MDR1 activation.

Upregulation of endothelial adhesion molecules by lysophosphatidylcholine. Involvement of G protein-coupled receptor GPR4.

Suppressive effects of bisphenol A on the proliferation of neural progenitor cells.

Di(2-ethylhexyl) phthalate induces apoptosis through peroxisome proliferators-activated receptor-gamma and ERK 1/2 activation in testis of Sprague-Dawley rats.

Retargeting of adenoviral gene delivery via Herceptin-PEG-adenovirus conjugates to breast cancer cells.

Carbon nanotube patterning with capillary micromolding of catalyst.

Cytotoxicity of 1,2-diacetylbenzene in human neuroblastoma SHSY5Y cells is mediated by oxidative stress.

Hollow silica nanocontainers as drug delivery vehicles.

Curcumin stimulates proliferation of embryonic neural progenitor cells and neurogenesis in the adult hippocampus.

Mitochondrial ATP synthase is a target for TNBS-induced protein carbonylation in XS-106 dendritic cells.

Hypothyroidism protects di(n-butyl) phthalate-induced reproductive organs damage in Sprague-Dawley male rats.

Cytoprotective roles of senescence marker protein 30 against intracellular calcium elevation and oxidative stress.

Vitamin C depletion increases superoxide generation in brains of SMP30/GNL knockout mice.

Time-response effects of testicular gene expression profiles in Sprague-Dawley male rats treated with di(n-butyl) phthalate.

Effects of trichostatin A, a histone deacetylase inhibitor, on the regulation of apoptosis in H-ras-transformed breast epithelial cells.

2-Deoxy-d-glucose protects neural progenitor cells against oxidative stress through the activation of AMP-activated protein kinase.

Mechanism of apicidin-induced cell cycle arrest and apoptosis in Ishikawa human endometrial cancer cells.

Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling.

The role of the Ser/Thr cluster in the phosphorylation of PPPSP motifs in Wnt coreceptors.

Adenine nucleotide translocator 1 deficiency increases resistance of mouse brain and neurons to excitotoxic insults.

Senescence marker protein 30 is up-regulated in kainate-induced hippocampal damage through ERK-mediated astrocytosis.

The anti-inflammatory effect of kaempferol in aged kidney tissues: the involvement of nuclear factor-kappaB via nuclear factor-inducing kinase/IkappaB kinase and mitogen-activated protein kinase pathways.

Neurotoxic effect of 2,5-hexanedione on neural progenitor cells and hippocampal neurogenesis.

Revealing system-level correlations between aging and calorie restriction using a mouse transcriptome.

Developmental and age-related changes of peptidylarginine deiminase 2 in the mouse brain.

Novel embryoid body-based method to derive mesenchymal stem cells from human embryonic stem cells.

Molecular activation of NF-kappaB, pro-inflammatory mediators, and signal pathways in gamma-irradiated mice.

Acrylamide induces cell death in neural progenitor cells and impairs hippocampal neurogenesis.

Effects of gestational exposure to decabromodiphenyl ether on reproductive parameters, thyroid hormone levels, and neuronal development in Sprague-Dawley rats offspring.

Exposure assessment of polybrominated diphenyl ethers (PBDE) in umbilical cord blood of Korean infants.

Potencies of bisphenol A on the neuronal differentiation and hippocampal neurogenesis.

Risk assessment for the combinational effects of food color additives: neural progenitor cells and hippocampal neurogenesis.

This month in APR.

Effect of the charge balance on high-efficiency blue-phosphorescent organic light-emitting diodes.

Molecular delineation of gamma-ray-induced NF-kappaB activation and pro-inflammatory genes in SMP30 knockout mice.

A high-fat diet impairs neurogenesis: involvement of lipid peroxidation and brain-derived neurotrophic factor.

Evaluation of liver and thyroid toxicity in Sprague-Dawley rats after exposure to polybrominated diphenyl ether BDE-209.

Capsaicin impairs proliferation of neural progenitor cells and hippocampal neurogenesis in young mice.

Functional role of phospholipase D (PLD) in di(2-ethylhexyl) phthalate-induced hepatotoxicity in Sprague-Dawley rats.

Adipokine resistin is a key player to modulate monocytes, endothelial cells, and smooth muscle cells, leading to progression of atherosclerosis in rabbit carotid artery.

COMP-Ang1 stimulates HIF-1α-mediated SDF-1 overexpression and recovers ischemic injury through BM-derived progenitor cell recruitment.

A novel epoxypropoxy flavonoid derivative and topoisomerase II inhibitor, MHY336, induces apoptosis in prostate cancer cells.

SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization.

The relationship between theta-gamma coupling and spatial memory ability in older adults.

Hyperoxia attenuates the inhibitory effect of nitric oxide donors on HIF prolyl-4-hydroxylase-2: Implication on discriminative effect of nitric oxide on HIF prolyl-4-hydroxylase-2 and collagen prolyl-4-hydroxylase.

Morin attenuates tau hyperphosphorylation by inhibiting GSK3β.

Neurogenic contributions made by dietary regulation to hippocampal neurogenesis.

Magnetic sensitivity enhanced novel fluorescent magnetic silica nanoparticles for biomedical applications.

Evaluation of antiangiogenic effects of a new synthetic candidate drug KR-31831 on xenografted ovarian carcinoma using dynamic contrast enhanced MRI.

Exposure to bisphenol A appears to impair hippocampal neurogenesis and spatial learning and memory.

Alpha amplitude and phase locking in obsessive-compulsive disorder during working memory.

A new synthetic HDAC inhibitor, MHY218, induces apoptosis or autophagy-related cell death in tamoxifen-resistant MCF-7 breast cancer cells.

Organic solvent metabolite, 1,2-diacetylbenzene, impairs neural progenitor cells and hippocampal neurogenesis.

The hepatoprotective effects of adenine nucleotide translocator-2 against aging and oxidative stress.

Interactive effects of background facial emotion stimulus and target salience on sustained attention performance in schizophrenia.

Chemopreventive mechanisms of methionine on inhibition of benzo(a)pyrene-DNA adducts formation in human hepatocellular carcinoma HepG2 cells.

Surface functionalized hollow manganese oxide nanoparticles for cancer targeted siRNA delivery and magnetic resonance imaging.

Comparisons of polybrominated diphenyl ethers levels in paired South Korean cord blood, maternal blood, and breast milk samples.

Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction.

Gender differences revealed in the right posterior temporal areas during Navon letter identification tasks.

Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer's disease.

High dose bisphenol A impairs hippocampal neurogenesis in female mice across generations.

Naphthazarin has a protective effect on the 1-methyl-4-phenyl-1,2,3,4-tetrahydropyridine-induced Parkinson's disease model.

Sirtinol, a class III HDAC inhibitor, induces apoptotic and autophagic cell death in MCF-7 human breast cancer cells.

Hypoxic priming of mESCs accelerates vascular-lineage differentiation through HIF1-mediated inverse regulation of Oct4 and VEGF.

Evaluation of metabolomic profiling against renal toxicity in Sprague-Dawley rats treated with melamine and cyanuric acid.

Baicalein attenuates impaired hippocampal neurogenesis and the neurocognitive deficits induced by γ-ray radiation.

Gamma oscillatory activity in relation to memory ability in older adults.

Resveratrol inhibits the proliferation of neural progenitor cells and hippocampal neurogenesis.

Senescence marker protein 30 deficiency increases Parkinson's pathology by impairing astrocyte activation.

Theta-gamma coupling during a working memory task as compared to a simple vigilance task.

Molecular mechanism of SAHA on regulation of autophagic cell death in tamoxifen-resistant MCF-7 breast cancer cells.

Selective impairment on the proliferation of neural progenitor cells by oxidative phosphorylation disruption.

Insufficient ascorbic acid intake during gestation induces abnormal cardiac dilation in fetal and neonatal SMP30/GNL knockout mice.

SIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism.

Development of Akt-activated GSK3β inhibitory peptide.

Elevated TRAF2/6 expression in Parkinson's disease is caused by the loss of Parkin E3 ligase activity.

Diallyl disulfide impairs hippocampal neurogenesis in the young adult brain.

Snail as a potential target molecule in cardiac fibrosis: paracrine action of endothelial cells on fibroblasts through snail and CTGF axis.

Resting-state beta and gamma activity in Internet addiction.

Correlation of risk-taking propensity with cross-frequency phase-amplitude coupling in the resting EEG.

A novel thermally reversible soluble-insoluble conjugated polymer with semi-fluorinated alkyl chains: enhanced transistor performance by fluorophobic self-organization and orthogonal hydrophobic patterning.

Baicalein attenuates astroglial activation in the 1-methyl-4-phenyl-1,2,3,4-tetrahydropyridine-induced Parkinson's disease model by downregulating the activations of nuclear factor-κB, ERK, and JNK.

Alcohol reduces cross-frequency theta-phase gamma-amplitude coupling in resting electroencephalography.

Molecular Mechanism of Tetrabromobisphenol A (TBBPA)-induced Target Organ Toxicity in Sprague-Dawley Male Rats.

Lipotoxicity of palmitic Acid on neural progenitor cells and hippocampal neurogenesis.

Computational modeling of the negative priming effect based on inhibition patterns and working memory.

Differential resting-state EEG patterns associated with comorbid depression in Internet addiction.

Development of a rabbit model for a preclinical comparison of coronary stent types in-vivo.

SIRT4 protein suppresses tumor formation in genetic models of Myc-induced B cell lymphoma.

Shared psychological characteristics that are linked to aggression between patients with Internet addiction and those with alcohol dependence.

Estimation of populations exposed to road traffic noise in districts of Seoul metropolitan area of Korea.

Adenylyl cyclase-associated protein 1 is a receptor for human resistin and mediates inflammatory actions of human monocytes.

Latent class analysis on internet and smartphone addiction in college students.

Adaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous system.

Neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis.

Activated platelet supernatant can augment the angiogenic potential of human peripheral blood stem cells mobilized from bone marrow by G-CSF.

Sphingosine 1-phosphate induced anti-atherogenic and atheroprotective M2 macrophage polarization through IL-4.

Donor-acceptor alternating copolymer nanowires for highly efficient organic solar cells.

Erythropoietin priming improves the vasculogenic potential of G-CSF mobilized human peripheral blood mononuclear cells.

Direct conversion of adult skin fibroblasts to endothelial cells by defined factors.

Viriditoxin regulates apoptosis and autophagy via mitotic catastrophe and microtubule formation in human prostate cancer cells.

Age-related inflammation and insulin resistance: a review of their intricate interdependency.

Evaluation of cadmium-induced nephrotoxicity using urinary metabolomic profiles in sprague-dawley male rats.

Psammaplin A induces Sirtuin 1-dependent autophagic cell death in doxorubicin-resistant MCF-7/adr human breast cancer cells and xenografts.

Transformation of Mouse Liver Cells by Methylcholanthrene Leads to Phenotypic Changes Associated with Epithelial-mesenchymal Transition.

Diagnostic utility of quantitative EEG in un-medicated schizophrenia.

Relationship between theta-phase gamma-amplitude coupling and attention-deficit/hyperactivity behavior in children.

MicroRNA-26a induced by hypoxia targets HDAC6 in myogenic differentiation of embryonic stem cells.

Silibinin prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease via mitochondrial stabilization.

Epigenetic modification and antibody-dependent expansion of memory-like NK cells in human cytomegalovirus-infected individuals.

Randomized Trial of Stents Versus Bypass Surgery for Left Main Coronary Artery Disease: 5-Year Outcomes of the PRECOMBAT Study.

Age-related sensitivity to endotoxin-induced liver inflammation: Implication of inflammasome/IL-1β for steatohepatitis.

Intersections between mitochondrial sirtuin signaling and tumor cell metabolism.

PMC-12, a Prescription of Traditional Korean Medicine, Improves Amyloid β-Induced Cognitive Deficits through Modulation of Neuroinflammation.

The mitochondrial uncoupler DNP triggers brain cell mTOR signaling network reprogramming and CREB pathway up-regulation.

Smart drug-loaded polymer gold nanoshells for systemic and localized therapy of human epithelial cancer.

Theta-phase gamma-amplitude coupling as a neurophysiological marker of attention deficit/hyperactivity disorder in children.

Colon-targeted delivery of budesonide using dual pH- and time-dependent polymeric nanoparticles for colitis therapy.

Naphthodithiophene-Based Conjugated Polymer with Linear, Planar Backbone Conformation and Strong Intermolecular Packing for Efficient Organic Solar Cells.

Comparative hyperthermia effects of silica-gold nanoshells with different surface coverage of gold clusters on epithelial tumor cells.

Silibinin suppresses astroglial activation in a mouse model of acute Parkinson's disease by modulating the ERK and JNK signaling pathways.

A Nonfullerene Small Molecule Acceptor with 3D Interlocking Geometry Enabling Efficient Organic Solar Cells.

Social Network Analysis Reveals the Negative Effects of Attention-Deficit/Hyperactivity Disorder (ADHD) Symptoms on Friend-Based Student Networks.

AKAP6 inhibition impairs myoblast differentiation and muscle regeneration: Positive loop between AKAP6 and myogenin.

Methylglyoxal Causes Cell Death in Neural Progenitor Cells and Impairs Adult Hippocampal Neurogenesis.

Formation and decay of charge carriers in aggregate nanofibers consisting of poly(3-hexylthiophene)-coated gold nanoparticles.

Is It Possible to Increase the Clinical Effectiveness of the Fracture Risk Assessment Tool in Osteopenia Patients by Taking Into Account Bone Mineral Density Values?

PMC-12, a traditional herbal medicine, enhances learning memory and hippocampal neurogenesis in mice.

Desynchronization of Theta-Phase Gamma-Amplitude Coupling during a Mental Arithmetic Task in Children with Attention Deficit/Hyperactivity Disorder.

Block Copolymer-Encapsulated CaWO4 Nanoparticles: Synthesis, Formulation, and Characterization.

RNA-Seq analysis reveals new evidence for inflammation-related changes in aged kidney.

Stable and biocompatible cystine knot peptides from the marine sponge Asteropus sp.

Neuroprotective and anti-inflammatory effects of morin in a murine model of Parkinson's disease.

Interaction between platelets and endothelial progenitor cells via LPA-Edg-2 axis is augmented by PPAR-δ activation.

Human gut-on-a-chip technology: will this revolutionize our understanding of IBD and future treatments?

Proximal Junctional Kyphosis: Diagnosis, Pathogenesis, and Treatment.

Neuroprotective effect of bee venom is mediated by reduced astrocyte activation in a subchronic MPTP-induced model of Parkinson's disease.

Tyrosinase inhibitory flavonoid from Juniperus communis fruits.