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Laurent Perrin

Department of Medical Specialties,
Division of Endocrinology,
Diabetes,
Hypertension and Nutrition,
Diabetes Center,
Department of Medical Specialties, Division of Endocrinology, Diabetes, Hypertension and Nutrition, Diabetes Center

University of Geneva Medical School, Institute of Genetics and Genomics in Geneva (iGE3)

BIOGRAPHY

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PUBLICATIONS

The leucine zipper motif of the Drosophila AF10 homologue can inhibit PRE-mediated repression: implications for leukemogenic activity of human MLL-AF10 fusions.

Molecular and cellular biology Jan, 2003 | Pubmed ID: 12482966

Modulo is a target of Myc selectively required for growth of proliferative cells in Drosophila.

Mechanisms of development Jun, 2003 | Pubmed ID: 12834864

[Genetic control of cardiac tube formation in Drosophila].

Journal de la Societe de biologie , 2003 | Pubmed ID: 12910631

Drosophila cardiac tube organogenesis requires multiple phases of Hox activity.

Developmental biology Aug, 2004 | Pubmed ID: 15282158

Steroid-dependent modification of Hox function drives myocyte reprogramming in the Drosophila heart.

Development (Cambridge, England) Dec, 2005 | Pubmed ID: 16284119

Control of cardiac rhythm by ORK1, a Drosophila two-pore domain potassium channel.

Current biology : CB Aug, 2006 | Pubmed ID: 16890525

Drosophila aging 2005/06.

Experimental gerontology Dec, 2006 | Pubmed ID: 17126511

Genetic control of heart function and aging in Drosophila.

Trends in cardiovascular medicine Jul, 2007 | Pubmed ID: 17574126

Signalling pathways involved in adult heart formation revealed by gene expression profiling in Drosophila.

PLoS genetics Oct, 2007 | Pubmed ID: 17937502

Circulating blood cells function as a surveillance system for damaged tissue in Drosophila larvae.

Proceedings of the National Academy of Sciences of the United States of America Jul, 2008 | Pubmed ID: 18632567

Downstream of homeotic genes: in the heart of Hox function.

Fly Mar-Apr, 2007 | Pubmed ID: 18820463

The fabulous destiny of the Drosophila heart.

Current opinion in genetics & development Oct, 2009 | Pubmed ID: 19717296

Response to mechanical stress is mediated by the TRPA channel painless in the Drosophila heart.

PLoS genetics Sep, 2010 | Pubmed ID: 20824071

Tissue-specific cell sorting from Drosophila embryos: application to gene expression analysis.

Fly Jul-Sep, 2011 | Pubmed ID: 21654211

Effects of omeprazole and genetic polymorphism of CYP2C19 on the clopidogrel active metabolite.

Drug metabolism and disposition: the biological fate of chemicals Jan, 2012 | Pubmed ID: 22004687

Insights into Hox protein function from a large scale combinatorial analysis of protein domains.

PLoS genetics Oct, 2011 | Pubmed ID: 22046139

Genes and networks regulating cardiac development and function in flies: genetic and functional genomic approaches.

Briefings in functional genomics Sep, 2012 | Pubmed ID: 22908209

Drosophila melanogaster Acetyl-CoA-carboxylase sustains a fatty acid-dependent remote signal to waterproof the respiratory system.

PLoS genetics , 2012 | Pubmed ID: 22956916

dJun and Vri/dNFIL3 are major regulators of cardiac aging in Drosophila.

PLoS genetics , 2012 | Pubmed ID: 23209438

Ndae1 expression and regulation in Drosophila embryos.

PloS one , 2014 | Pubmed ID: 24676142

Identification of cis-regulatory modules encoding temporal dynamics during development.

BMC genomics Jun, 2014 | Pubmed ID: 24972496

Tissue specific RNA isolation in Drosophila embryos: a strategy to analyze context dependent transcriptome landscapes using FACS.

Methods in molecular biology (Clifton, N.J.) , 2014 | Pubmed ID: 25151164

LedPred: an R/bioconductor package to predict regulatory sequences using support vector machines.

Bioinformatics (Oxford, England) Apr, 2016 | Pubmed ID: 26628586

Human skeletal myotubes display a cell-autonomous circadian clock implicated in basal myokine secretion.

Molecular metabolism Nov, 2015 | Pubmed ID: 26629407

[Cardiac pathologies and aging: lessons from a tiny heart].

Medecine sciences : M/S May, 2016 | Pubmed ID: 27225919

A Randomized Phase 1 Study to Assess the Safety and Pharmacokinetics of the Subcutaneously Injected Anti-LIGHT Antibody, SAR252067.

Clinical pharmacology in drug development Aug, 2016 | Pubmed ID: 27545119

Qualitative Dynamical Modelling Can Formally Explain Mesoderm Specification and Predict Novel Developmental Phenotypes.

PLoS computational biology Sep, 2016 | Pubmed ID: 27599298

INSTITUTIONS

University of Geneva Medical School, Institute of Genetics and Genomics in Geneva (iGE3)

JOVE ARTICLES

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures

Volodymyr Petrenko^*,1,

Camille Saini^*,2,

Laurent Perrin^*,1,

Charna Dibner¹

¹Department of Medical Specialties, Division of Endocrinology, Diabetes, Hypertension and Nutrition, Diabetes Center, University of Geneva Medical School, Institute of Genetics and Genomics in Geneva (iGE3),

²Population Epidemiology Unit (UEP), Community Medicine, Geneva University Hospital

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