Institute of Experimental Biomedicine
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JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes.
Nature immunology Feb, 2002 | Pubmed ID: 11812992
Suppression of endothelial adhesion molecule up-regulation with cyclopentenone prostaglandins is dissociated from IkappaB-alpha kinase inhibition and cell death induction.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jun, 2003 | Pubmed ID: 12692090
Residual mesorectal lymph node involvement following neoadjuvant combined-modality therapy: rationale for radical resection?
Annals of surgical oncology Feb, 2004 | Pubmed ID: 14761922
Cyclopentenone prostaglandins induce endothelial cell apoptosis independent of the peroxisome proliferator-activated receptor-gamma.
European journal of immunology Jan, 2004 | Pubmed ID: 14971050
Chemokines: key regulators of mononuclear cell recruitment in atherosclerotic vascular disease.
Arteriosclerosis, thrombosis, and vascular biology Nov, 2004 | Pubmed ID: 15319268
Targeted disruption of cd73/ecto-5'-nucleotidase alters thromboregulation and augments vascular inflammatory response.
Circulation research Oct, 2004 | Pubmed ID: 15358667
Crucial role of the CCL2/CCR2 axis in neointimal hyperplasia after arterial injury in hyperlipidemic mice involves early monocyte recruitment and CCL2 presentation on platelets.
Circulation research Nov, 2004 | Pubmed ID: 15528472
Inflammatory mediators in atherosclerotic vascular disease.
Basic research in cardiology Mar, 2005 | Pubmed ID: 15645164
Involvement of JAM-A in mononuclear cell recruitment on inflamed or atherosclerotic endothelium: inhibition by soluble JAM-A.
Arteriosclerosis, thrombosis, and vascular biology Apr, 2005 | Pubmed ID: 15681301
Transplantation of human umbilical vein endothelial cells improves left ventricular function in a rat model of myocardial infarction.
Basic research in cardiology May, 2005 | Pubmed ID: 15690102
SDF-1alpha/CXCR4 axis is instrumental in neointimal hyperplasia and recruitment of smooth muscle progenitor cells.
Circulation research Apr, 2005 | Pubmed ID: 15761195
Platelet microparticles: a transcellular delivery system for RANTES promoting monocyte recruitment on endothelium.
Arteriosclerosis, thrombosis, and vascular biology Jul, 2005 | Pubmed ID: 15890969
Reduction of the aortic inflammatory response in spontaneous atherosclerosis by blockade of macrophage migration inhibitory factor (MIF).
Atherosclerosis Jan, 2006 | Pubmed ID: 15921687
Importance of junctional adhesion molecule-A for neointimal lesion formation and infiltration in atherosclerosis-prone mice.
Arteriosclerosis, thrombosis, and vascular biology Feb, 2006 | Pubmed ID: 16306427
Deficiency in CCR5 but not CCR1 protects against neointima formation in atherosclerosis-prone mice: involvement of IL-10.
Blood Jun, 2006 | Pubmed ID: 16467202
Thienopyridines in percutaneous coronary interventions: standard procedures and high risk subsets.
Current pharmaceutical design , 2006 | Pubmed ID: 16611112
CD73/ecto-5'-nucleotidase protects against vascular inflammation and neointima formation.
Circulation May, 2006 | Pubmed ID: 16636171
MCP-1 induces a novel transcription factor with proapoptotic activity.
Circulation research May, 2006 | Pubmed ID: 16690887
SDF-1alpha-mediated tissue repair by stem cells: a promising tool in cardiovascular medicine?
Trends in cardiovascular medicine May, 2006 | Pubmed ID: 16713531
Vascular endothelial growth factor-A induces plaque expansion in ApoE knock-out mice by promoting de novo leukocyte recruitment.
Blood Jan, 2007 | Pubmed ID: 16990600
Ccr5 but not Ccr1 deficiency reduces development of diet-induced atherosclerosis in mice.
Arteriosclerosis, thrombosis, and vascular biology Feb, 2007 | Pubmed ID: 17138939
Chemokines: inflammatory mediators of atherosclerosis.
Archives of physiology and biochemistry Oct-Dec, 2006 | Pubmed ID: 17178596
Importance of CXC chemokine receptor 2 in the homing of human peripheral blood endothelial progenitor cells to sites of arterial injury.
Circulation research Mar, 2007 | Pubmed ID: 17272812
MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment.
Nature medicine May, 2007 | Pubmed ID: 17435771
Perivascular mast cells promote atherogenesis and induce plaque destabilization in apolipoprotein E-deficient mice.
Circulation May, 2007 | Pubmed ID: 17470698
Chemokines in vascular remodeling.
Thrombosis and haemostasis May, 2007 | Pubmed ID: 17479183
Regulation of endothelial progenitor cell homing after arterial injury.
Thrombosis and haemostasis Aug, 2007 | Pubmed ID: 17721606
Y-box binding protein-1 controls CC chemokine ligand-5 (CCL5) expression in smooth muscle cells and contributes to neointima formation in atherosclerosis-prone mice.
Circulation Oct, 2007 | Pubmed ID: 17893273
Expression of HIF-1alpha in injured arteries controls SDF-1alpha mediated neointima formation in apolipoprotein E deficient mice.
Arteriosclerosis, thrombosis, and vascular biology Dec, 2007 | Pubmed ID: 17932320
Protective role of CXC receptor 4/CXC ligand 12 unveils the importance of neutrophils in atherosclerosis.
Circulation research Feb, 2008 | Pubmed ID: 17991882
C1-esterase inhibitor protects against neointima formation after arterial injury in atherosclerosis-prone mice.
Circulation Jan, 2008 | Pubmed ID: 18071075
The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling.
Blood May, 2008 | Pubmed ID: 18195092
Macrophage migration inhibitory factor in cardiovascular disease.
Circulation Mar, 2008 | Pubmed ID: 18362243
Role of smooth muscle cGMP/cGKI signaling in murine vascular restenosis.
Arteriosclerosis, thrombosis, and vascular biology Jul, 2008 | Pubmed ID: 18420996
Neutrophil secretion products pave the way for inflammatory monocytes.
Blood Aug, 2008 | Pubmed ID: 18490516
Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation.
The Journal of experimental medicine Jun, 2008 | Pubmed ID: 18519646
Chemokines in atherosclerosis: an update.
Arteriosclerosis, thrombosis, and vascular biology Nov, 2008 | Pubmed ID: 18566299
Adult progenitor cells in vascular remodeling during atherosclerosis.
Biological chemistry Jul, 2008 | Pubmed ID: 18627306
Blockade of angio-associated migratory cell protein inhibits smooth muscle cell migration and neointima formation in accelerated atherosclerosis.
Journal of the American College of Cardiology Jul, 2008 | Pubmed ID: 18634987
Caffeine enhances endothelial repair by an AMPK-dependent mechanism.
Arteriosclerosis, thrombosis, and vascular biology Nov, 2008 | Pubmed ID: 18757291
Dynamic changes in murine vessel geometry assessed by high-resolution magnetic resonance angiography: a 9.4T study.
Journal of magnetic resonance imaging : JMRI Sep, 2008 | Pubmed ID: 18777558
The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models.
Nature reviews. Immunology Oct, 2008 | Pubmed ID: 18825131
Structural determinants of MIF functions in CXCR2-mediated inflammatory and atherogenic leukocyte recruitment.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2008 | Pubmed ID: 18852457
CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival.
Blood Jan, 2009 | Pubmed ID: 18971423
Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice.
Nature medicine Jan, 2009 | Pubmed ID: 19122657
Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases.
Blood May, 2009 | Pubmed ID: 19258599
Importance of junctional adhesion molecule-C for neointimal hyperplasia and monocyte recruitment in atherosclerosis-prone mice-brief report.
Arteriosclerosis, thrombosis, and vascular biology Aug, 2009 | Pubmed ID: 19520977
Neutrophils launch monocyte extravasation by release of granule proteins.
Thrombosis and haemostasis Aug, 2009 | Pubmed ID: 19652869
Alteration of matrix metalloproteinases in selective left ventricular adriamycin-induced cardiomyopathy in the pig.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation Oct, 2009 | Pubmed ID: 19782292
Evaluation of a novel system for hypothermic oxygenated pulsatile perfusion preservation.
The International journal of artificial organs Oct, 2009 | Pubmed ID: 19943234
Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection.
Science signaling Dec, 2009 | Pubmed ID: 19996457
Chemokines in the vascular inflammatory response of atherosclerosis.
Cardiovascular research May, 2010 | Pubmed ID: 20007309
Soluble CD40 ligand impairs the function of peripheral blood angiogenic outgrowth cells and increases neointimal formation after arterial injury.
Circulation Jan, 2010 | Pubmed ID: 20048211
Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile.
The Journal of experimental medicine Feb, 2010 | Pubmed ID: 20100871
Functional contribution of elevated circulating and hepatic non-classical CD14CD16 monocytes to inflammation and human liver fibrosis.
PloS one Jun, 2010 | Pubmed ID: 20548789
Myeloid type I interferon signaling promotes atherosclerosis by stimulating macrophage recruitment to lesions.
Cell metabolism Aug, 2010 | Pubmed ID: 20674859
Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis.
Blood Nov, 2010 | Pubmed ID: 20705757
C5a receptor targeting in neointima formation after arterial injury in atherosclerosis-prone mice.
Circulation Sep, 2010 | Pubmed ID: 20733098
A new monocyte chemotactic protein-1/chemokine CC motif ligand-2 competitor limiting neointima formation and myocardial ischemia/reperfusion injury in mice.
Journal of the American College of Cardiology Nov, 2010 | Pubmed ID: 21087715
Role of the CX3C chemokine receptor CX3CR1 in the pathogenesis of atherosclerosis after aortic transplantation.
PloS one , 2017 | Pubmed ID: 28234900
MIF-chemokine receptor interactions in atherogenesis are dependent on an N-loop-based 2-site binding mechanism.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Mar, 2011 | Pubmed ID: 21106938
Non- invasive in vivo analysis of a murine aortic graft using high resolution ultrasound microimaging.
European journal of radiology Feb, 2012 | Pubmed ID: 21334152
Complement C5a inhibition reduces atherosclerosis in ApoE-/- mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jul, 2011 | Pubmed ID: 21490292
The soluble CTLA-4 splice variant protects from type 1 diabetes and potentiates regulatory T-cell function.
Diabetes Jul, 2011 | Pubmed ID: 21602513
CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice.
The Journal of clinical investigation Jul, 2011 | Pubmed ID: 21633167
Neutrophil-derived cathelicidin protects from neointimal hyperplasia.
Science translational medicine Oct, 2011 | Pubmed ID: 21974936
Double-edged role of the CXCL12/CXCR4 axis in experimental myocardial infarction.
Journal of the American College of Cardiology Nov, 2011 | Pubmed ID: 22115649
microRNAs in the regulation of dendritic cell functions in inflammation and atherosclerosis.
Journal of molecular medicine (Berlin, Germany) Aug, 2012 | Pubmed ID: 22307520
Auto-antigenic protein-DNA complexes stimulate plasmacytoid dendritic cells to promote atherosclerosis.
Circulation Apr, 2012 | Pubmed ID: 22388324
Hematopoietic interferon regulatory factor 8-deficiency accelerates atherosclerosis in mice.
Arteriosclerosis, thrombosis, and vascular biology Jul, 2012 | Pubmed ID: 22556330
Plasmacytoid dendritic cells in atherosclerosis.
Frontiers in physiology , 2012 | Pubmed ID: 22754539
Visualization of vascular inflammation in the atherosclerotic mouse by ultrasmall superparamagnetic iron oxide vascular cell adhesion molecule-1-specific nanoparticles.
Arteriosclerosis, thrombosis, and vascular biology Oct, 2012 | Pubmed ID: 22879583
Pathophysiological mechanisms of carotid plaque vulnerability: impact on ischemic stroke.
Archivum immunologiae et therapiae experimentalis Dec, 2012 | Pubmed ID: 22945688
Improving the treatment of atherosclerosis by linking anti-inflammatory and lipid modulating strategies.
Heart (British Cardiac Society) Nov, 2012 | Pubmed ID: 23086996
Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature.
Blood Jan, 2013 | Pubmed ID: 23160472
Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes.
EMBO molecular medicine Mar, 2013 | Pubmed ID: 23417922
Early venous manifestation of Ehlers-Danlos syndrome Type IV through a novel mutation in COL3A1.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology Nov-Dec, 2013 | Pubmed ID: 23688910
Endothelial junctional adhesion molecule-a guides monocytes into flow-dependent predilection sites of atherosclerosis.
Circulation Jan, 2014 | Pubmed ID: 24065611
CCR6 selectively promotes monocyte mediated inflammation and atherogenesis in mice.
Thrombosis and haemostasis Dec, 2013 | Pubmed ID: 24114205
Role of extracellular RNA in atherosclerotic plaque formation in mice.
Circulation Feb, 2014 | Pubmed ID: 24201302
Molecular imaging of inflammation in atherosclerosis.
Theranostics Nov, 2013 | Pubmed ID: 24312156
Chemokines in atherosclerosis: proceedings resumed.
Arteriosclerosis, thrombosis, and vascular biology Apr, 2014 | Pubmed ID: 24436368
Bone marrow-specific knock-in of a non-activatable Ikkα kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice.
PloS one , 2014 | Pubmed ID: 24498325
Controlled intramyocardial release of engineered chemokines by biodegradable hydrogels as a treatment approach of myocardial infarction.
Journal of cellular and molecular medicine May, 2014 | Pubmed ID: 24512349
Dendritic cell subset distributions in the aorta in healthy and atherosclerotic mice.
PloS one , 2014 | Pubmed ID: 24551105
Programmed Cell Death-1 Deficiency Exacerbates T Cell Activation and Atherogenesis despite Expansion of Regulatory T Cells in Atherosclerosis-Prone Mice.
PloS one , 2014 | Pubmed ID: 24691202
CXCR4 blockade induces atherosclerosis by affecting neutrophil function.
Journal of molecular and cellular cardiology Sep, 2014 | Pubmed ID: 24816217
Distinct functions of specialized dendritic cell subsets in atherosclerosis and the road ahead.
Scientifica , 2014 | Pubmed ID: 24818041
Quantitative expression and localization of cysteine and aspartic proteases in human abdominal aortic aneurysms.
Experimental & molecular medicine May, 2014 | Pubmed ID: 24833013
Noncoding RNAs in vascular inflammation and atherosclerosis: recent advances toward therapeutic applications.
Current opinion in lipidology Oct, 2014 | Pubmed ID: 25051497
Establishment of a new murine elastase-induced aneurysm model combined with transplantation.
PloS one , 2014 | Pubmed ID: 25068788
Response to letter regarding article "Role of extracellular RNA in atherosclerotic plaque formation in mice".
Circulation Oct, 2014 | Pubmed ID: 25311624
STAT1-dependent signal integration between IFNγ and TLR4 in vascular cells reflect pro-atherogenic responses in human atherosclerosis.
PloS one , 2014 | Pubmed ID: 25478796
The hemostatic system as a regulator of inflammation in atherosclerosis.
IUBMB life Nov, 2014 | Pubmed ID: 25491152
Echogenic perfluorohexane-loaded macrophages adhere in vivo to activated vascular endothelium in mice, an explorative study.
Cardiovascular ultrasound , 2015 | Pubmed ID: 25567641
Dendritic cells in atherosclerosis: evidence in mice and humans.
Arteriosclerosis, thrombosis, and vascular biology Apr, 2015 | Pubmed ID: 25675999
Macrophages and immune cells in atherosclerosis: recent advances and novel concepts.
Basic research in cardiology , 2015 | Pubmed ID: 25947006
CD8+ T Cells Regulate Monopoiesis and Circulating Ly6C-high Monocyte Levels in Atherosclerosis in Mice.
Circulation research Jul, 2015 | Pubmed ID: 25991812
Stimulating arteriogenesis but not atherosclerosis: IFN-α/β receptor subunit 1 as a novel therapeutic target.
Cardiovascular research Jul, 2015 | Pubmed ID: 26084309
Deficiency of HIF1α in Antigen-Presenting Cells Aggravates Atherosclerosis and Type 1 T-Helper Cell Responses in Mice.
Arteriosclerosis, thrombosis, and vascular biology Nov, 2015 | Pubmed ID: 26404487
Carotid Plaque Morphology Is Significantly Associated With Sex, Age, and History of Neurological Symptoms.
Stroke Nov, 2015 | Pubmed ID: 26451032
Efficacy and Safety of Platelet Glycoprotein Receptor Blockade in Aged and Comorbid Mice With Acute Experimental Stroke.
Stroke; a journal of cerebral circulation Dec, 2015 | Pubmed ID: 26486866
Histone acetylation and methylation significantly change with severity of atherosclerosis in human carotid plaques.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology Mar-Apr, 2016 | Pubmed ID: 26764138
Histone acetylation and histone acetyltransferases show significant alterations in human abdominal aortic aneurysm.
Clinical epigenetics , 2016 | Pubmed ID: 26767057
Aneurysm miRNA Signature Differs, Depending on Disease Localization and Morphology.
International journal of molecular sciences Jan, 2016 | Pubmed ID: 26771601
Extracellular Ribonucleic Acids (RNA) Enter the Stage in Cardiovascular Disease.
Circulation research Feb, 2016 | Pubmed ID: 26846641
Targeting In-Stent-Stenosis with RGD- and CXCL1-Coated Mini-Stents in Mice.
PloS one , 2016 | Pubmed ID: 27192172
Regulation of matrix metalloproteinases (MMPs) expression and secretion in MDA-MB-231 breast cancer cells by LIM and SH3 protein 1 (LASP1).
Oncotarget Sep, 2016 | Pubmed ID: 27588391
Increased intermediate CD14(++)CD16(++) monocyte subset levels associate with restenosis after peripheral percutaneous transluminal angioplasty.
Atherosclerosis Oct, 2016 | Pubmed ID: 27615596
Protective and pathogenic roles of CD8(+) T cells in atherosclerosis.
Basic research in cardiology Nov, 2016 | Pubmed ID: 27783202
Coagulation factor XII induces pro-inflammatory cytokine responses in macrophages and promotes atherosclerosis in mice.
Thrombosis and haemostasis Jan, 2017 | Pubmed ID: 27786338
Congenital valvular defects associated with deleterious mutations in the PLD1 gene.
Journal of medical genetics Apr, 2017 | Pubmed ID: 27799408
CD98 promotes vascular smooth muscle cell accumulation in atherosclerosis to confer plaque stability.
Atherosclerosis Jan, 2017 | Pubmed ID: 27939649
The "Intermediate" CD14(++)CD16(+) monocyte subset increases in severe peripheral artery disease in humans.
Scientific reports Dec, 2016 | Pubmed ID: 27991581
Targeting Elastase for Molecular Imaging of Early Atherosclerotic Lesions.
Arteriosclerosis, thrombosis, and vascular biology Mar, 2017 | Pubmed ID: 28062502
Macrophages in vascular inflammation and atherosclerosis.
Pflugers Archiv : European journal of physiology Apr, 2017 | Pubmed ID: 28168325
Visualization of endothelial barrier damage prior to formation of atherosclerotic plaques.
Histochemistry and cell biology Aug, 2017 | Pubmed ID: 28343238
Deletion of Batf3-dependent antigen-presenting cells does not affect atherosclerotic lesion formation in mice.
PloS one , 2017 | Pubmed ID: 28771609
Hypercholesterolemia induced cerebral small vessel disease.
PloS one , 2017 | Pubmed ID: 28796818
Antigen-presenting dendritic cells in atherosclerosis.
European journal of pharmacology Aug, 2017 | Pubmed ID: 28822856
Cell differentiation defines acute and chronic infection cell types in Staphylococcus aureus.
eLife Sep, 2017 | Pubmed ID: 28893374
Extracellular Cyclophilin A Augments Platelet-Dependent Thrombosis and Thromboinflammation.
Thrombosis and haemostasis Oct, 2017 | Pubmed ID: 28981554
Zuzanna Rowinska1,2,
Simone Gorressen3,
Marc W. Merx4,
Thomas A. Koeppel5,
Alma Zernecke6,
Elisa A. Liehn2
1Department of Vascular Surgery and Interdisciplinary Vein Center, St. Josef-Hospital, Ruhr- University Bochum,
2Institute of Molecular Cardiovascular Research, University Hospital, RWTH Aachen University Department of Medicine,
3Institute of Pharmacology and Clinical Pharmacology, Düsseldorf University Hospital,
4Department of Cardiology, Vascular Medicine and Intensive Care Medicine, Hospital Robert Koch Gehrden,
5Division of Vascular Surgery, Asklepios Klinik St. Georg,
6Institute of Experimental Biomedicine, Würzburg University
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