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Developmental Biology Program
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Biological responses of suspension cultures of Taxus chinensis var. mairei to shear stresses in the short term.
Applied biochemistry and biotechnology Aug, 2003 | Pubmed ID: 14515022
Rat aortic smooth muscle cells contract in response to serum and its components in a calcium independent manner.
Annals of biomedical engineering Dec, 2004 | Pubmed ID: 15675680
Effects of fluid shear stress on adventitial fibroblast migration: implications for flow-mediated mechanisms of arterialization and intimal hyperplasia.
American journal of physiology. Heart and circulatory physiology Jun, 2007 | Pubmed ID: 17308005
Interstitial flow promotes vascular fibroblast, myofibroblast, and smooth muscle cell motility in 3-D collagen I via upregulation of MMP-1.
American journal of physiology. Heart and circulatory physiology Oct, 2009 | Pubmed ID: 19465549
Interstitial flow induces MMP-1 expression and vascular SMC migration in collagen I gels via an ERK1/2-dependent and c-Jun-mediated mechanism.
American journal of physiology. Heart and circulatory physiology Jan, 2010 | Pubmed ID: 19880665
Permeability of endothelial and astrocyte cocultures: in vitro blood-brain barrier models for drug delivery studies.
Annals of biomedical engineering Aug, 2010 | Pubmed ID: 20361260
Shear stress modulation of smooth muscle cell marker genes in 2-D and 3-D depends on mechanotransduction by heparan sulfate proteoglycans and ERK1/2.
PloS one Aug, 2010 | Pubmed ID: 20808940
Heparan sulfate proteoglycans mediate interstitial flow mechanotransduction regulating MMP-13 expression and cell motility via FAK-ERK in 3D collagen.
PloS one Jan, 2011 | Pubmed ID: 21246051
Fluid flow mechanotransduction in vascular smooth muscle cells and fibroblasts.
Annals of biomedical engineering Jun, 2011 | Pubmed ID: 21479754
Fluid shear stress regulates the invasive potential of glioma cells via modulation of migratory activity and matrix metalloproteinase expression.
PloS one , 2011 | Pubmed ID: 21637818
Heparan sulfate proteoglycan mediates shear stress-induced endothelial gene expression in mouse embryonic stem cell-derived endothelial cells.
Biotechnology and bioengineering Feb, 2012 | Pubmed ID: 21837663
Effect of the glycocalyx layer on transmission of interstitial flow shear stress to embedded cells.
Biomechanics and modeling in mechanobiology Jan, 2013 | Pubmed ID: 22411016
Enhanced osteogenesis of human mesenchymal stem cells by periodic heat shock in self-assembling peptide hydrogel.
Tissue engineering. Part A Mar, 2013 | Pubmed ID: 23072422
Homologous recombination DNA repair genes play a critical role in reprogramming to a pluripotent state.
Cell reports Mar, 2013 | Pubmed ID: 23478019
Cancer cell glycocalyx mediates mechanotransduction and flow-regulated invasion.
Integrative biology : quantitative biosciences from nano to macro Nov, 2013 | Pubmed ID: 24077103
An iCRISPR platform for rapid, multiplexable, and inducible genome editing in human pluripotent stem cells.
Cell stem cell Aug, 2014 | Pubmed ID: 24931489
Fluid Mechanics, Arterial Disease, and Gene Expression.
Annual review of fluid mechanics Jan, 2014 | Pubmed ID: 25360054
A CRISPR/Cas-Mediated Selection-free Knockin Strategy in Human Embryonic Stem Cells.
Stem cell reports Jun, 2015 | Pubmed ID: 26028531
Heparan sulfate proteoglycans mediate renal carcinoma metastasis.
International journal of cancer Dec, 2016 | Pubmed ID: 27543953
Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development.
Cell stem cell Feb, 2017 | Pubmed ID: 28196600
Sloan Kettering Institute
Zhong-Dong Shi*,1,
Chew-Li Soh*,1,
Zengrong Zhu*,1,
Danwei Huangfu1
1Developmental Biology Program, Sloan Kettering Institute
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