Kelly T. Dineley

Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice.

Beta-amyloid peptide--nicotinic acetylcholine receptor interaction: the two faces of health and disease.

Selective induction of calcineurin activity and signaling by oligomeric amyloid beta.

Intermediate- and long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition.

Loss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease.

Amyloid-beta oligomers impair fear conditioned memory in a calcineurin-dependent fashion in mice.

Rosiglitazone reversal of Tg2576 cognitive deficits is independent of peripheral gluco-regulatory status.

α-Synuclein oligomers oppose long-term potentiation and impair memory through a calcineurin-dependent mechanism: relevance to human synucleopathic diseases.

α7 nicotinic acetylcholine receptors in Alzheimer's disease: neuroprotective, neurotrophic or both?

Cognitive enhancement with rosiglitazone links the hippocampal PPARγ and ERK MAPK signaling pathways.

Enhanced leptin sensitivity, reduced adiposity, and improved glucose homeostasis in mice lacking exchange protein directly activated by cyclic AMP isoform 1.

Ruthenium red colorimetric and birefringent staining of amyloid-β aggregates in vitro and in Tg2576 mice.

Cognitive enhancing treatment with a PPARγ agonist normalizes dentate granule cell presynaptic function in Tg2576 APP mice.

PPARγ recruitment to active ERK during memory consolidation is required for Alzheimer's disease-related cognitive enhancement.

Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles.

Research tool: Validation of floxed α7 nicotinic acetylcholine receptor conditional knockout mice using in vitro and in vivo approaches.

Insulin resistance in Alzheimer's disease.

Impaired firing properties of dentate granule neurons in an Alzheimer's disease animal model are rescued by PPARγ agonism.

Nicotinic ACh receptors as therapeutic targets in CNS disorders.

Animal Model of Sensorineural Hearing Loss Associated with Lassa Virus Infection.

Neurological Sequelae Resulting from Encephalitic Alphavirus Infection.

Behavioural and neurological symptoms accompanied by cellular neuroinflammation in IL-10-deficient mice infected with Plasmodium chabaudi.

Aged dominant negative p38α MAPK mice are resistant to age-dependent decline in adult-neurogenesis and context discrimination fear conditioning.

Mouse Model of Neurological Complications Resulting from Encephalitic Alphavirus Infection.

Septal Cholinergic Neuromodulation Tunes the Astrocyte-Dependent Gating of Hippocampal NMDA Receptors to Wakefulness.

PPAR-gamma agonist pioglitazone modifies craving intensity and brain white matter integrity in patients with primary cocaine use disorder: a double-blind randomized controlled pilot trial.

PPARgamma agonists rescue increased phosphorylation of FGF14 at S226 in the Tg2576 mouse model of Alzheimer's disease.

Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease.

Spatial and Sex-Dependent Responses of Adult Endogenous Neural Stem Cells to Alcohol Consumption.

Acute inhalation of combustion smoke triggers neuroinflammation and persistent anxiety-like behavior in the mouse.

Cocaine evokes a profile of oxidative stress and impacts innate antiviral response pathways in astrocytes.

Targeting Insulin for Alzheimer's Disease: Mechanisms, Status and Potential Directions.