Alex Groisman

Microfluidic memory and control devices.

A microfluidic rectifier: anisotropic flow resistance at low Reynolds numbers.

Chaotic flow and efficient mixing in a microchannel with a polymer solution.

Chaotic mixing in a steady flow in a microchannel.

A microfluidic chemostat for experiments with bacterial and yeast cells.

Separation of plasma from whole human blood in a continuous cross-flow in a molded microfluidic device.

Microtargeted gene silencing and ectopic expression in live embryos using biolistic delivery with a pneumatic capillary gun.

High-throughput and high-resolution flow cytometry in molded microfluidic devices.

Perfusion in microfluidic cross-flow: separation of white blood cells from whole blood and exchange of medium in a continuous flow.

Generation of complex concentration profiles in microchannels in a logarithmically small number of steps.

Quantitative measurements of the strength of adhesion of human neutrophils to a substratum in a microfluidic device.

MAPK-mediated bimodal gene expression and adaptive gradient sensing in yeast.

Bound attractant at the leading vs. the trailing edge determines chemotactic prowess.

Self-organization in high-density bacterial colonies: efficient crowd control.

Localized alpha4 integrin phosphorylation directs shear stress-induced endothelial cell alignment.

Bioluminescent response of individual dinoflagellate cells to hydrodynamic stress measured with millisecond resolution in a microfluidic device.

Optofluidic 1x4 switch.

Integrin-mediated protein kinase A activation at the leading edge of migrating cells.

Microfluidic devices for studies of shear-dependent platelet adhesion.

Fine temporal control of the medium gas content and acidity and on-chip generation of series of oxygen concentrations for cell cultures.

An easy to assemble microfluidic perfusion device with a magnetic clamp.

Set of two orthogonal adaptive cylindrical lenses in a monolith elastomer device.

High-resolution temperature-concentration diagram of alpha-synuclein conformation obtained from a single Förster resonance energy transfer image in a microfluidic device.

Microfluidic device for single-molecule experiments with enhanced photostability.

Generation of oxygen gradients with arbitrary shapes in a microfluidic device.

Ultrafast microfluidic mixer with three-dimensional flow focusing for studies of biochemical kinetics.

External and internal constraints on eukaryotic chemotaxis.

Gradient sensing in defined chemotactic fields.

Visualizing a one-way protein encounter complex by ultrafast single-molecule mixing.

Live cell imaging of paxillin in rolling neutrophils by dual-color quantitative dynamic footprinting.

Protein kinase A governs a RhoA-RhoGDI protrusion-retraction pacemaker in migrating cells.

Acute drug treatment in the early C. elegans embryo.

High refractive index silicone gels for simultaneous total internal reflection fluorescence and traction force microscopy of adherent cells.

Measurements of elastic moduli of silicone gel substrates with a microfluidic device.

Incoherent feedforward control governs adaptation of activated ras in a eukaryotic chemotaxis pathway.