Department of Experimental Medical Science,
Wallenberg Neuroscience Center,
Division of Neurobiology and Lund Stem Cell Center,
Department of Experimental Medical Science, Wallenberg Neuroscience Center, Division of Neurobiology and Lund Stem Cell Center
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Regional specification of neurosphere cultures derived from subregions of the embryonic telencephalon.
Molecular and cellular neurosciences Dec, 2002 | Pubmed ID: 12504597
A transplantation study of expanded human embryonic forebrain precursors: evidence for selection of a specific progenitor population.
Molecular and cellular neurosciences Aug, 2003 | Pubmed ID: 12932435
Phenotypic and molecular identity of cells in the adult subventricular zone. in vivo and after expansion in vitro.
Molecular and cellular neurosciences Nov, 2003 | Pubmed ID: 14664822
Striatal neuron differentiation from neurosphere-expanded progenitors depends on Gsh2 expression.
The Journal of neuroscience : the official journal of the Society for Neuroscience Aug, 2004 | Pubmed ID: 15295031
Neurogenin2 identifies a transplantable dopamine neuron precursor in the developing ventral mesencephalon.
Experimental neurology Mar, 2006 | Pubmed ID: 16438966
Retrovirally delivered Islet-1 increases recruitment of Ng2 expressing cells from the postnatal SVZ into the striatum.
Experimental neurology Oct, 2006 | Pubmed ID: 16806175
In vitro characterization of a human neural progenitor cell coexpressing SSEA4 and CD133.
Journal of neuroscience research Feb, 2007 | Pubmed ID: 17131412
Ngn2 and Nurr1 act in synergy to induce midbrain dopaminergic neurons from expanded neural stem and progenitor cells.
Experimental cell research Apr, 2007 | Pubmed ID: 17291494
Strengths and limitations of the neurosphere culture system.
Molecular neurobiology Dec, 2006 | Pubmed ID: 17308349
Early specification of dopaminergic phenotype during ES cell differentiation.
BMC developmental biology Jul, 2007 | Pubmed ID: 17640353
Reprogramming of neonatal SVZ progenitors by islet-1 and neurogenin-2.
Molecular and cellular neurosciences Jul, 2008 | Pubmed ID: 18524626
Dopamine neuron precursors within the developing human mesencephalon show radial glial characteristics.
Glia Nov, 2009 | Pubmed ID: 19330857
Organization of the human embryonic ventral mesencephalon.
Gene expression patterns : GEP Dec, 2009 | Pubmed ID: 19825428
Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2010 | Pubmed ID: 20534548
Neural grafting in Parkinson's disease Problems and possibilities.
Progress in brain research , 2010 | Pubmed ID: 20887880
Direct conversion of human fibroblasts to dopaminergic neurons.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2011 | Pubmed ID: 21646515
Turning skin into dopamine neurons.
Cell research Oct, 2011 | Pubmed ID: 21826107
Efficient induction of functional neurons from adult human fibroblasts.
Cell cycle (Georgetown, Tex.) Oct, 2011 | Pubmed ID: 21934358
Generation of transplantable striatal projection neurons from human ESCs.
Cell stem cell Apr, 2012 | Pubmed ID: 22482498
Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment.
The Journal of clinical investigation Aug, 2012 | Pubmed ID: 22751106
Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditions.
Cell reports Jun, 2012 | Pubmed ID: 22813745
Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens.
Neurobiology of disease Jan, 2013 | Pubmed ID: 22940632
Generating regionalized neuronal cells from pluripotency, a step-by-step protocol.
Frontiers in cellular neuroscience , 2012 | Pubmed ID: 23316134
Generation of induced neurons via direct conversion in vivo.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2013 | Pubmed ID: 23530235
Human foetal brain tissue as quality control when developing stem cells towards cell replacement therapy for neurological diseases.
Neuroreport Dec, 2013 | Pubmed ID: 24257249
The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons.
Acta neuropathologica Feb, 2014 | Pubmed ID: 24292008
Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation.
Stem cell reports Mar, 2014 | Pubmed ID: 24672756
Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain.
Scientific reports Sep, 2014 | Pubmed ID: 25208484
Direct neural conversion from human fibroblasts using self-regulating and nonintegrating viral vectors.
Cell reports Dec, 2014 | Pubmed ID: 25482564
Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease.
Cell stem cell Nov, 2014 | Pubmed ID: 25517469
Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons.
Stem cell reports Jun, 2015 | Pubmed ID: 26004633
In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry.
Cell reports Jul, 2015 | Pubmed ID: 26166567
Cell-based therapies for Parkinson disease—past insights and future potential.
Nature reviews. Neurology Sep, 2015 | Pubmed ID: 26240036
Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor.
Development (Cambridge, England) Sep, 2015 | Pubmed ID: 26395143
In Vivo Reprogramming for Brain and Spinal Cord Repair.
eNeuro Sep-Oct, 2015 | Pubmed ID: 26730402
Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016?
Journal of Parkinson's disease , 2016 | Pubmed ID: 27003785
DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor.
Neuron Jun, 2016 | Pubmed ID: 27161524
hESC-derived neural progenitors prevent xenograft rejection through neonatal desensitisation.
Experimental neurology Aug, 2016 | Pubmed ID: 27235932
Comparability: manufacturing, characterization and controls, report of a UK Regenerative Medicine Platform Pluripotent Stem Cell Platform Workshop, Trinity Hall, Cambridge, 14-15 September 2015.
Regenerative medicine Jul, 2016 | Pubmed ID: 27404768
Plug and Play Brain: Understanding Integration of Transplanted Neurons for Brain Repair.
Cell stem cell 12, 2016 | Pubmed ID: 27912087
Small molecules increase direct neural conversion of human fibroblasts.
Scientific reports Dec, 2016 | Pubmed ID: 27917895
TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells.
Cell reports Jan, 2017 | Pubmed ID: 28052240
Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease.
Cell stem cell Jan, 2017 | Pubmed ID: 28094017
Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages.
Cell stem cell Jan, 2017 | Pubmed ID: 28094018
Synaptic inputs from stroke-injured brain to grafted human stem cell-derived neurons activated by sensory stimuli.
Brain : a journal of neurology Mar, 2017 | Pubmed ID: 28115364
Strategies for bringing stem cell-derived dopamine neurons to the clinic: A European approach (STEM-PD).
Progress in brain research , 2017 | Pubmed ID: 28552228
REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways.
EMBO molecular medicine Aug, 2017 | Pubmed ID: 28646119
Term amniotic fluid: an unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications.
Stem cell research & therapy Aug, 2017 | Pubmed ID: 28841906
Direct Reprogramming of Resident NG2 Glia into Neurons with Properties of Fast-Spiking Parvalbumin-Containing Interneurons.
Stem cell reports Sep, 2017 | Pubmed ID: 28844658
Generation of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation.
Nature protocols Sep, 2017 | Pubmed ID: 28858290
Human iPS cell-derived dopaminergic neurons function in a primate Parkinson's disease model.
Nature 08, 2017 | Pubmed ID: 28858313
IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells.
Stem cell reports Oct, 2017 | Pubmed ID: 28943253
Direct Neuronal Reprogramming for Disease Modeling Studies Using Patient-Derived Neurons: What Have We Learned?
Frontiers in neuroscience , 2017 | Pubmed ID: 29033781
Human Trials of Stem Cell-Derived Dopamine Neurons for Parkinson's Disease: Dawn of a New Era.
Cell stem cell Nov, 2017 | Pubmed ID: 29100010
Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming.
Cell stem cell Dec, 2017 | Pubmed ID: 29174331
Towards stem cell based therapies for Parkinson's disease.
Development (Cambridge, England) Jan, 2018 | Pubmed ID: 29311261
Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus.
Stem cells international , 2017 | Pubmed ID: 29317869
1Department of Experimental Medical Science, Wallenberg Neuroscience Center, Division of Neurobiology and Lund Stem Cell Center, Lund University,
2John van Geest Centre for Brain Repair & Department of Neurology, Department of Clinical Neurosciences and Cambridge Stem Cell Institute, University of Cambridge
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