mouse-adipose-tissue-collection-and-processing-for-rna-analysis

Mouse Adipose Tissue Collection and Processing for RNA Analysis

Compared to other tissues, white adipose tissue has a considerably less RNA and protein content for downstream applications such as real-time PCR and ...

Université de Montréal

Administration of the handle region peptide (HRP), a (pro)renin receptor blocker, decreases body weight gain and visceral adipose tissue (VAT) in high-fat/high-carbohydrate (HF/HC) diet-fed mice. The objective of this study was to elucidate potential mechanisms implicated in these observations.

Prorenin/renin receptor blockade promotes a healthy fat distribution in obese mice.

We previously demonstrated that the handle-region peptide, a prorenin/renin receptor [(P)RR] blocker, reduces body weight and fat mass and may improve insulin sensitivity in high-fat fed mice. We hypothesized that knocking out the adipose tissue (P)RR gene would prevent weight gain and insulin resistance.

Paul Tan

Centre de Recherche du Centre Hospitalier,
Department of Biochemistry and Molecular Medicine

Université de Montréal

Mouse Adipose Tissue Collection and Processing for RNA Analysis

Paul Tan

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Centre de Recherche du Centre Hospitalier,Department of Biochemistry and Molecular Medicine

Université de Montréal

Mouse Adipose Tissue Collection and Processing for RNA Analysis

Centre de Recherche du Centre Hospitalier,
Department of Biochemistry and Molecular Medicine