Theodore P. Rasmussen

Chromosomal silencing and localization are mediated by different domains of Xist RNA.

BRCA1 supports XIST RNA concentration on the inactive X chromosome.

Embryonic stem cell differentiation: a chromatin perspective.

A maternal store of macroH2A is removed from pronuclei prior to onset of somatic macroH2A expression in preimplantation embryos.

DNA CpG hypomethylation induces heterochromatin reorganization involving the histone variant macroH2A.

Reprogramming mediated by stem cell fusion.

Genome-wide reprogramming in hybrids of somatic cells and embryonic stem cells.

Global epiproteomic signatures distinguish embryonic stem cells from differentiated cells.

HDAC3 overexpression and colon cancer cell proliferation and differentiation.

Developmentally-poised chromatin of embryonic stem cells.

HDAC3 impacts multiple oncogenic pathways in colon cancer cells with effects on Wnt and vitamin D signaling.

ES cell cycle progression and differentiation require the action of the histone methyltransferase Dot1L.

Progressive accumulation of epigenetic heterogeneity during human ES cell culture.

Epigenetic regulatory mechanisms during preimplantation development.

Rapid elimination of the histone variant MacroH2A from somatic cell heterochromatin after nuclear transfer.

Targeting DOT1L action and interactions in leukemia: the role of DOT1L in transformation and development.

Epigenetic pre-patterning and dynamics during initial stages of mammalian preimplantation development.

Skeletal muscle stem cells from animals I. Basic cell biology.

Lipid metabolism, adipocyte depot physiology and utilization of meat animals as experimental models for metabolic research.

Natural and artificial routes to pluripotency.

X chromosome inactivation and differentiation occur readily in ES cells doubly-deficient for macroH2A1 and macroH2A2.