Vittorio Sartorelli

IL-6 Blockade as a Therapeutic Approach for Duchenne Muscular Dystrophy.

Proteasome-mediated degradation of the coactivator p300 impairs cardiac transcription.

HERP, a new primary target of Notch regulated by ligand binding.

HERP, a novel heterodimer partner of HES/E(spl) in Notch signaling.

The link between chromatin structure, protein acetylation and cellular differentiation.

Stage-specific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases.

Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state.

Deacetylase inhibitors increase muscle cell size by promoting myoblast recruitment and fusion through induction of follistatin.

Tax relieves transcriptional repression by promoting histone deacetylase 1 release from the human T-cell leukemia virus type 1 long terminal repeat.

Molecular and cellular determinants of skeletal muscle atrophy and hypertrophy.

The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation.

Mechanisms underlying the transcriptional regulation of skeletal myogenesis.

Fgfr4 is required for effective muscle regeneration in vivo. Delineation of a MyoD-Tead2-Fgfr4 transcriptional pathway.

Follistatin induction by nitric oxide through cyclic GMP: a tightly regulated signaling pathway that controls myoblast fusion.

The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation.

The DEAD-box p68/p72 proteins and the noncoding RNA steroid receptor activator SRA: eclectic regulators of disparate biological functions.

MyoD acetylation influences temporal patterns of skeletal muscle gene expression.

Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt.

Comparing and contrasting the roles of AMPK and SIRT1 in metabolic tissues.

Mir-214-dependent regulation of the polycomb protein Ezh2 in skeletal muscle and embryonic stem cells.

MicroRNA-214 and polycomb group proteins: a regulatory circuit controlling differentiation and cell fate decisions.

Dietary restriction: standing up for sirtuins.

TNF/p38α/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration.

Myc-nick: the force behind c-Myc.

Phosphoryl-EZH-ion.

Polycomb EZH2 controls self-renewal and safeguards the transcriptional identity of skeletal muscle stem cells.

Sculpting chromatin beyond the double helix: epigenetic control of skeletal myogenesis.

Decreased microRNA-214 levels in breast cancer cells coincides with increased cell proliferation, invasion and accumulation of the Polycomb Ezh2 methyltransferase.

Polycomb protein Ezh1 promotes RNA polymerase II elongation.

Who needs microtubules? Myogenic reorganization of MTOC, Golgi complex and ER exit sites persists despite lack of normal microtubule tracks.

STATs shape the active enhancer landscape of T cell populations.

The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis.

BACH2 represses effector programs to stabilize T(reg)-mediated immune homeostasis.

The methyltransferase SMYD3 mediates the recruitment of transcriptional cofactors at the myostatin and c-Met genes and regulates skeletal muscle atrophy.

eRNAs promote transcription by establishing chromatin accessibility at defined genomic loci.

Interactome maps of mouse gene regulatory domains reveal basic principles of transcriptional regulation.

H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.

The emerging roles of eRNAs in transcriptional regulatory networks.

An evolutionarily biased distribution of miRNA sites toward regulatory genes with high promoter-driven intrinsic transcriptional noise.

Gcn5 and PCAF regulate PPARγ and Prdm16 expression to facilitate brown adipogenesis.

The NAD(+)-dependent SIRT1 deacetylase translates a metabolic switch into regulatory epigenetics in skeletal muscle stem cells.

Super-enhancers delineate disease-associated regulatory nodes in T cells.

EZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansion.

Metabolic Reprogramming of Stem Cell Epigenetics.

The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1.

Polycomb Ezh2 controls the fate of GABAergic neurons in the embryonic cerebellum.

Laminopathies disrupt epigenomic developmental programs and cell fate.

S6K1ing to ResTOR Adipogenesis with Polycomb.

Roles of H3K27me2 and H3K27me3 Examined during Fate Specification of Embryonic Stem Cells.

Specific Sirt1 Activator-mediated Improvement in Glucose Homeostasis Requires Sirt1-Independent Activation of AMPK.

The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins.

ATP Citrate Lyase: A New Player Linking Skeletal Muscle Metabolism and Epigenetics.

Single cell analysis of adult mouse skeletal muscle stem cells in homeostatic and regenerative conditions.