Margaret A. Goodell

Hematopoietic potential of stem cells isolated from murine skeletal muscle.

Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells.

Muscle-derived hematopoietic stem cells are hematopoietic in origin.

Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population.

Stem cells: a minireview.

Use of CD9 expression to enrich for porcine hematopoietic progenitors.

The therapeutic potential of stem cells from adults.

Failure of bone marrow cells to transdifferentiate into neural cells in vivo.

Anti-CD45-mediated cytoreduction to facilitate allogeneic stem cell transplantation.

Distinct progenitor populations in skeletal muscle are bone marrow derived and exhibit different cell fates during vascular regeneration.

Tracing the origin of non-hematopoietic cells using CD45 PCR restriction fragment length polymorphisms.

Techniques for the study of adult stem cells: be fruitful and multiply.

Adenoviral transduction of mouse hematopoietic stem cells.

Stem-cell "plasticity": befuddled by the muddle.

Complement-fixing CD45 monoclonal antibodies to facilitate stem cell transplantation in mouse and man.

Phenotype and hematopoietic potential of side population cells throughout embryonic development.

Transient RNA interference in hematopoietic progenitors with functional consequences.

Altered phenotype and reduced function of muscle-derived hematopoietic stem cells.

Isolation and characterization of functional mammary gland stem cells.

Single hematopoietic stem cells generate skeletal muscle through myeloid intermediates.

Primitive adult hematopoietic stem cells can function as osteoblast precursors.

An in vivo propagated human acute myeloid leukemia expressing ABCA3.

Skeletal muscle fiber-specific green autofluorescence: potential for stem cell engraftment artifacts.

Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage.

Hematopoietic myelomonocytic cells are the major source of hepatocyte fusion partners.

Circulating hematopoietic stem cells do not efficiently home to bone marrow during homeostasis.

Isolation and characterization of side population cells.

Molecular signatures of proliferation and quiescence in hematopoietic stem cells.

Roles of Sca-1 in hematopoietic stem/progenitor cell function.

Hematopoietic stem cells do not engraft with absolute efficiencies.

Differential mRNA processing in hematopoietic stem cells.

Evidence for diversity in transcriptional profiles of single hematopoietic stem cells.

The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging.

Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways.

Plasticity and tissue regenerative potential of bone marrow-derived cells.

Purification of hematopoietic stem cells using the side population.

Pluripotentiality and conditional transgene regulation in human embryonic stem cells expressing insulated tetracycline-ON transactivator.

Molecular profiling of hematopoietic stem cells.

Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation.

Efficacy of delayed administration of post-chemotherapy granulocyte colony-stimulating factor: evidence from murine studies of bone marrow cell kinetics.

CD150- side population cells represent a functionally distinct population of long-term hematopoietic stem cells.

An argument against a role for Oct4 in somatic stem cells.

Hematopoietic fingerprints: an expression database of stem cells and their progeny.

Promiscuous expression of H2B-GFP transgene in hematopoietic stem cells.

Stem cell identification and sorting using the Hoechst 33342 side population (SP).

Mouse hematopoietic stem cell identification and analysis.

Identification and characterization of side population cells in embryonic stem cell cultures.

Adult hematopoietic stem and progenitor cells require either Lyl1 or Scl for survival.

Selective depletion of a minor subpopulation of B-chronic lymphocytic leukemia cells is followed by a delayed but progressive loss of bulk tumor cells and disease regression.

Enhanced generation of myeloid lineages in hematopoietic differentiation from embryonic stem cells by silencing transcriptional repressor Twist-2.

Mechanisms of hematopoietic stem cell aging.

Chk1 haploinsufficiency results in anemia and defective erythropoiesis.

Selective elimination of a chemoresistant side population of B-CLL cells by cytotoxic T lymphocytes in subjects receiving an autologous hCD40L/IL-2 tumor vaccine.

Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells.

Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1.

Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection.

The expansion of T-cells and hematopoietic progenitors as a result of overexpression of the lymphoblastic leukemia gene, Lyl1 can support leukemia formation.

LYL1 degradation by the proteasome is directed by a N-terminal PEST rich site in a phosphorylation-independent manner.

The orphan nuclear receptor Nurr1 restricts the proliferation of haematopoietic stem cells.

Inflammatory signals regulate hematopoietic stem cells.

Polymorphic allele of human IRGM1 is associated with susceptibility to tuberculosis in African Americans.

Direct conversion of skin cells into blood: alchemy or science?

A new allele of Lyl1 confirms its important role in hematopoietic stem cell function.

Investigating the role of hematopoietic stem and progenitor cells in regulating the osteogenic differentiation of mesenchymal stem cells in vitro.

TIMP-1 deficiency subverts cell-cycle dynamics in murine long-term HSCs.

CD48 on hematopoietic progenitors regulates stem cells and suppresses tumor formation.

Hematopoietic stem cell characterization and isolation.

Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling.

Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response.

CD81 is essential for the re-entry of hematopoietic stem cells to quiescence following stress-induced proliferation via deactivation of the Akt pathway.

Bridge over troubled stem cells.

Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells.

Dnmt3a is essential for hematopoietic stem cell differentiation.

Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing.

The Hematopoietic Expression Viewer: expanding mobile apps as a scientific tool.

Genomic hypomethylation in the human germline associates with selective structural mutability in the human genome.

Flow cytometry analysis of murine hematopoietic stem cells.

The transcription factor Lyl-1 regulates lymphoid specification and the maintenance of early T lineage progenitors.

Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice.

Gpr171, a putative P2Y-like receptor, negatively regulates myeloid differentiation in murine hematopoietic progenitors.

Isolation and characterization of mouse side population cells.

Confounding by repetitive elements and CpG islands does not explain the association between hypomethylation and genomic instability.

Ataxin1L is a regulator of HSC function highlighting the utility of cross-tissue comparisons for gene discovery.

Perspectives and future directions for epigenetics in hematology.

Rising from the crypt: decreasing DNA methylation during differentiation of the small intestine.

Ten-eleven translocation 1 (Tet1) is regulated by O-linked N-acetylglucosamine transferase (Ogt) for target gene repression in mouse embryonic stem cells.

Parental permissions: H19 and keeping the stem cell progeny under control.

A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells.

Large conserved domains of low DNA methylation maintained by Dnmt3a.

Hematopoietic stem cell development: an epigenetic journey.

MOABS: model based analysis of bisulfite sequencing data.

Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal.

mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert).

A gallon of sweat to make a pint of blood.

New answers to old questions from genome-wide maps of DNA methylation in hematopoietic cells.

Dnmt3a and Dnmt3b have overlapping and distinct functions in hematopoietic stem cells.

Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation.

DNMT3A in haematological malignancies.

Long non-coding RNAs control hematopoietic stem cell function.

Somatic stem cell heterogeneity: diversity in the blood, skin and intestinal stem cell compartments.

Comparative long-term effects of interferon α and hydroxyurea on human hematopoietic progenitor cells.

Comparison of Cesium-137 and X-ray Irradiators by Using Bone Marrow Transplant Reconstitution in C57BL/6J Mice.

Acute loss of TET function results in aggressive myeloid cancer in mice.

Stem cells and healthy aging.

Noncoding Regulatory RNAs in Hematopoiesis.

Mixed-phenotype acute leukemia (MPAL) exhibits frequent mutations in DNMT3A and activated signaling genes.

DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias.

DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia.

DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells.

Oncometabolite d-2-hydroxyglutarate impairs α-ketoglutarate dehydrogenase and contractile function in rodent heart.

Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9.

DNMT3A in Leukemia.

Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein.

Genome-Wide Analysis of DNA Methylation in Hematopoietic Cells: DNA Methylation Analysis by WGBS.

DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A.

Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma.

Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo.