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Discovery of 2-arylamino-4-(1-methyl-3-isopropylsulfonyl-4-pyrazol-amino)pyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors.
Bioorganic & medicinal chemistry letters Jun, 2015 | Pubmed ID: 26130408
Design and synthesis of novel 3-sulfonylpyrazol-4-amino pyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors.
Bioorganic & medicinal chemistry letters Apr, 2016 | Pubmed ID: 26979157
Molecular Pathology of Patient Tumors, Patient-Derived Xenografts, and Cancer Cell Lines.
Cancer research 08, 2016 | Pubmed ID: 27325646
Nuclear Export of Ubiquitinated Proteins Determines the Sensitivity of Colorectal Cancer to Proteasome Inhibitor.
Molecular cancer therapeutics 04, 2017 | Pubmed ID: 27903750
Experimental animal modeling for immuno-oncology.
Pharmacology & therapeutics May, 2017 | Pubmed ID: 28167217
EGFR gene status predicts response and survival benefit in a preclinical gastric cancer trial treating patient‑derived xenografts with cetuximab.
Oncology reports Oct, 2017 | Pubmed ID: 28849161
Anti‑cancer effects of a novel Pan‑RAF inhibitor in a hepatocellular carcinoma cell line.
Molecular medicine reports Apr, 2018 | Pubmed ID: 29484394
Crown Bioscience Inc.
Peking University
Xiaoyu An*,1,2,
Xuesong Ouyang*,1,
Hui Zhang1,
Tingting Li1,
Yu-yang Huang1,
Zhiyuan Li1,
Demin Zhou2,
Qi-Xang Li1,2
1, Crown Bioscience Inc.,
2State Key Laboratory of Natural and Biomimetic Drugs, Peking University
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