Department of Mechanical Engineering
Jiahuan Chen is a technologist in charge in the State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College.
She started her research training (Master degree) at North West Agriculture and Forestry University, where she focused on stem cell biology (2008 to 2011). After working in a bio-company for about two years (2011 to 2013), she decided to return to academia and pursuit her PhD degree on immunology at School of Medicine Tsinghua University. Her thesis focused on biophysical aspects of regulation T cell (Treg) function. She probed the binding force between two cells directly by using atomic force microscopy (AFM)-based single-cell force spectroscopy (SCFS). She found that Treg cells displays an unusually high binding strength to dendritic cells (DCs) compared to conventional T cells. This binding blocked DCs’ ability to present antigens to other T cells, thus revealing a biophysical aspect of Treg cell biology. She obtained her Ph.D. in 2018 from the Tsinghua University. And in the same year, she was recruited as a technologist in charge at Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences. Her current work focused on the application and development of new technologies in the field of biomedical research.
Distinct non-clock-like signatures of the basal cell carcinomas from three sisters with a lethal Gorlin-Goltz syndrome.
BMC medical genomics Aug, 2022 | Pubmed ID: 35932013
The influence of one-carbon metabolism on gene promoter methylation in a population-based breast cancer study.
Epigenetics Nov, 2011 | Pubmed ID: 22048254
DNA methylation in peripheral blood measured by LUMA is associated with breast cancer in a population-based study.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jun, 2012 | Pubmed ID: 22371529
Global DNA Methylation, Measured by the Luminometric Methylation Assay (LUMA), Associates with Postmenopausal Breast Cancer in Non-Obese and Physically Active Women.
Journal of Cancer , 2015 | Pubmed ID: 26000047
Gene-Specific Promoter Methylation Status in Hormone-Receptor-Positive Breast Cancer Associates with Postmenopausal Body Size and Recreational Physical Activity.
International journal of cancer and clinical research , 2015 | Pubmed ID: 26005715
Polycyclic aromatic hydrocarbon (PAH)-DNA adducts and breast cancer: modification by gene promoter methylation in a population-based study.
Cancer causes & control : CCC Dec, 2015 | Pubmed ID: 26407953
Antimicrobial blue light inactivation of Candida albicans: In vitro and in vivo studies.
Virulence Jul, 2016 | Pubmed ID: 26909654
Nevus Sebaceous of Jadassohn With Eight Secondary Tumors of Follicular, Sebaceous, and Sweat Gland Differentiation.
The American Journal of dermatopathology Nov, 2016 | Pubmed ID: 27097338
In situ photoimmunotherapy for cutaneous granuloma caused by itraconazole-resistant Candida guilliermondii.
Dermatologic therapy Sep, 2016 | Pubmed ID: 27328828
Plum-blossom needling promoted PpIX fluorescence intensity from 5-aminolevulinic acid in porcine skin model and patients with actnic keratosis.
Photodiagnosis and photodynamic therapy Sep, 2016 | Pubmed ID: 27375183
A Negative Feedback Loop Between Autophagy and Immune Responses in Mycobacterium leprae Infection.
DNA and cell biology Jan, 2017 | Pubmed ID: 27854511
Successful treatment of Rosai-Dorfman disease using photoimmunotherapy.
Indian journal of dermatology, venereology and leprology , 2017 | Pubmed ID: 28366926
Multiple distant painful subcutaneous nodules in a healthy young non-smoker.
The Australasian journal of dermatology Nov, 2017 | Pubmed ID: 28718872
Activation and overexpression of the aryl hydrocarbon receptor contribute to cutaneous squamous cell carcinomas: an immunohistochemical study.
Diagnostic pathology Aug, 2018 | Pubmed ID: 30144817
Live inhibits autophagy and apoptosis of infected macrophages and prevents engulfment of host cell by phagocytes.
American journal of translational research , 2018 | Pubmed ID: 30323879
Airway microbiome is associated with respiratory functions and responses to ambient particulate matter exposure.
Ecotoxicology and environmental safety Jan, 2019 | Pubmed ID: 30342360
[Historical review of reprogramming and pluripotent stem cell research in China].
Yi chuan = Hereditas Oct, 2018 | Pubmed ID: 30369467
Genetic regulation of the placental transcriptome underlies birth weight and risk of childhood obesity.
PLoS genetics Dec, 2018 | Pubmed ID: 30596636
Identification of key candidate genes involved in melanoma metastasis.
Molecular medicine reports Aug, 2019 | Pubmed ID: 31173190
Circulating osteocalcin: A potential predictor of ketosis in type 2 diabetes.
Diabetes/metabolism research and reviews May, 2020 | Pubmed ID: 31850672
Distinguishing rosacea from sensitive skin by reflectance confocal microscopy.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) Sep, 2020 | Pubmed ID: 32180258
Efficacy and safety of Tripterygium wilfordii Hook. f. for oral lichen planus: Evidence from 18 randomized controlled trials.
Phytotherapy research : PTR Sep, 2020 | Pubmed ID: 32180273
Imaging findings of Bowen's disease: A comparison between ultrasound biomicroscopy and conventional high-frequency ultrasound.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) Sep, 2020 | Pubmed ID: 32196763
Interleukin-33 alleviates psoriatic inflammation by suppressing the T helper type 17 immune response.
Immunology Aug, 2020 | Pubmed ID: 32306382
Prenatal exposure to ambient air multi-pollutants significantly impairs intrauterine fetal development trajectory.
Ecotoxicology and environmental safety May, 2020 | Pubmed ID: 32480160
CD4/CD8 dual-positive mycosis fungoides: A case report and literature review.
Medicine Oct, 2020 | Pubmed ID: 33080750
Chronic Exposure to PM Nitrate, Sulfate, and Ammonium Causes Respiratory System Impairments in Mice.
Environmental science & technology Mar, 2021 | Pubmed ID: 33566583
Maxing Shigan Decoction Mitigates -Induced Pyroptosis in A549 Cells via the NLRP3 Inflammasome.
Infection and drug resistance , 2021 | Pubmed ID: 33688221
Docetaxel maintenance therapy versus best supportive care after first-line chemotherapy with different dose docetaxel plus cisplatin for advanced non-small cell lung cancer (TFINE study, CTONG-0904): an open-label, randomized, phase III trial.
Annals of translational medicine Feb, 2021 | Pubmed ID: 33708965
Revealing consensus gene pathways associated with respiratory functions and disrupted by PM2.5 nitrate exposure at bulk tissue and single cell resolution.
Environmental pollution (Barking, Essex : 1987) Jul, 2021 | Pubmed ID: 33780843
Percutaneous Endoscopic Lumbar Discectomy via Transforaminal Approach Combined with Interlaminar Approach for L4/5 and L5/S1 Two-Level Disc Herniation.
Orthopaedic surgery May, 2021 | Pubmed ID: 33821557
Internal Migration and Leprosy in Shanghai from 2000 to 2019: an Epidemiological Study of New Cases.
Acta dermato-venereologica May, 2021 | Pubmed ID: 33954796
A case of tripterygium glycosides-associated AGEP-like drug reaction combined with bullous pemphigoid.
Dermatologic therapy Jul, 2021 | Pubmed ID: 34060189
Upper Lumbar Intradural Disc Herniation: A Rare Case Report and Etiologic Analysis.
Journal of pain research , 2021 | Pubmed ID: 34079362
Peg-interferon alpha add-on Tenofovir disoproxil fumarate achieved more HBsAg loss in HBeAg-positive chronic hepatitis B naïve patients.
Journal of viral hepatitis Oct, 2021 | Pubmed ID: 34228855
Elevated Expressions of BTN3A1 and RhoB in Psoriasis Vulgaris Lesions by an Immunohistochemical Study.
Applied immunohistochemistry & molecular morphology : AIMM Feb, 2022 | Pubmed ID: 34545848
Upregulation of GTPBP4 Promotes the Proliferation of Liver Cancer Cells.
Journal of oncology , 2021 | Pubmed ID: 34712323
Antibody-free profiling of transcription factor occupancy during early embryogenesis by FitCUT&RUN.
Genome research Feb, 2022 | Pubmed ID: 34965941
Nitric oxide in multikinase inhibitor-induced hand-foot skin reaction.
Translational research : the journal of laboratory and clinical medicine Jul, 2022 | Pubmed ID: 35189405
A case of primary cutaneous anaplastic large cell lymphoma on eyelid.
Indian journal of dermatology, venereology and leprology , 2022 | Pubmed ID: 35389030
Exploration of the Potential Mechanism of the Common Differentially Expressed Genes in Psoriasis and Atopic Dermatitis.
BioMed research international , 2022 | Pubmed ID: 35586812
Analyzing the influence of COVID-19 epidemic on the employment intention of resident physicians in China.
Journal of infection in developing countries Jun, 2022 | Pubmed ID: 35797295
Post-Translational Modifications in Atopic Dermatitis: Current Research and Clinical Relevance.
Frontiers in cell and developmental biology , 2022 | Pubmed ID: 35874824
Within- and cross-tissue gene regulations were disrupted by PM nitrate exposure and associated with respiratory functions.
The Science of the total environment Dec, 2022 | Pubmed ID: 35964746
Measuring the indirect cost associated with advanced non-small cell lung cancer: a nationwide cross-sectional study in China.
Journal of cancer research and clinical oncology Jul, 2023 | Pubmed ID: 36056953
Sagittal alignment of the cervical spine: radiographic analysis of 111 asymptomatic adolescents, a retrospective observational study.
BMC musculoskeletal disorders Sep, 2022 | Pubmed ID: 36057594
Cutaneous allergic reaction to subcutaneous vitamin K: A case report and review of literature.
World journal of clinical cases Oct, 2022 | Pubmed ID: 36312487
Analytical performance of rapid nucleic acid detection assays and routine RT-qPCR assays for detection of SARS-CoV-2 in Shanghai, China in 2022.
Diagnostic microbiology and infectious disease Feb, 2023 | Pubmed ID: 36459887
Effects of chronic electronic cigarettes exposure in inducing respiratory function decline and pulmonary tissue injury - A direct comparison to combustible cigarettes.
Ecotoxicology and environmental safety Jan, 2023 | Pubmed ID: 36525947
Iso-Kikuchi syndrome: report of a Chinese case.
Clinical and experimental dermatology Jan, 2023 | Pubmed ID: 36669182
Ethnic disparities in ambient air and traffic-related pollution exposure and ethnic-specific impacts on clinical biomarker levels.
The Science of the total environment May, 2023 | Pubmed ID: 36841400
Demographic and clinical feature disparity between progress and non-progress patients with vitiligo after COVID-19 vaccination: A cross-sectional study.
Experimental dermatology Sep, 2023 | Pubmed ID: 37140178
Minimally invasive transforaminal lumbar interbody fusion by a novel two-medium compatible bichannel endoscopy system, technique note and preliminary clinical results.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society Aug, 2023 | Pubmed ID: 37160442
Measuring direct non-medical burden among patients with advanced non-small cell lung cancer in China: is there a difference in health status?
Frontiers in public health , 2023 | Pubmed ID: 37213608
Clinical guideline on magnetically controlled capsule gastroscopy (2021 edition).
Journal of digestive diseases Feb, 2023 | Pubmed ID: 37220999
TWEAK Progress in Dermatology: A Review.
Indian journal of dermatology , 2023 | Pubmed ID: 37822396
Multiple gene-drug prediction tool reveals Rosiglitazone based treatment pathway for non-segmental vitiligo.
Inflammation Apr, 2024 | Pubmed ID: 38159176
Does caring for patients with advanced non-small cell lung cancer affect health-related quality of life of caregivers? A multicenter, cross-sectional study.
BMC public health Jan, 2024 | Pubmed ID: 38238722
A Case of Palmoplantar Porokeratosis With Hypokeratosis: A New Subtype of Porokeratosis?
The American Journal of dermatopathology Dec, 2024 | Pubmed ID: 38842349
Prenatal exposure to PM led to impaired respiratory function in adult mice.
Ecotoxicology and environmental safety Oct, 2024 | Pubmed ID: 39299211
A New Pilot Hole Preparation System for Percutaneous Pedicle Screw Placement: A Randomized Controlled Study.
Spine Jan, 2025 | Pubmed ID: 39394652
Case report: A rollercoaster journey of pemphigus vegetans.
Frontiers in immunology , 2024 | Pubmed ID: 39872528
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