Department of Pathology
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Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history.
PLoS genetics Jan, 2006 | Pubmed ID: 16440057
Splice variation in the cytoplasmic domains of myelin oligodendrocyte glycoprotein affects its cellular localisation and transport.
Journal of neurochemistry Sep, 2007 | Pubmed ID: 17573820
Variation analysis and gene annotation of eight MHC haplotypes: the MHC Haplotype Project.
Immunogenetics Jan, 2008 | Pubmed ID: 18193213
Human MHC architecture and evolution: implications for disease association studies.
International journal of immunogenetics Jun, 2008 | Pubmed ID: 18397301
Cellular expression, trafficking, and function of two isoforms of human ULBP5/RAET1G.
PloS one , 2009 | Pubmed ID: 19223974
Mechanisms of copy number variation and hybrid gene formation in the KIR immune gene complex.
Human molecular genetics Mar, 2010 | Pubmed ID: 19959527
Genetic variation, Fcγ receptors, KIRs and infection: the evolution of autoimmunity.
Current opinion in immunology Dec, 2010 | Pubmed ID: 21050737
Electrostatic modifications of the human leukocyte antigen-DR P9 peptide-binding pocket and susceptibility to primary sclerosing cholangitis.
Hepatology (Baltimore, Md.) Jun, 2011 | Pubmed ID: 21413052
Copy number variation leads to considerable diversity for B but not A haplotypes of the human KIR genes encoding NK cell receptors.
Genome research Oct, 2012 | Pubmed ID: 22948769
Killer cell immunoglobulin-like receptor (KIR) genes and their HLA-C ligands in a Ugandan population.
Immunogenetics Nov, 2013 | Pubmed ID: 23974321
Copy number and nucleotide variation of the LILR family of myelomonocytic cell activating and inhibitory receptors.
Immunogenetics Feb, 2014 | Pubmed ID: 24257760
TAPBPR isoforms exhibit altered association with MHC class I.
Immunology Jun, 2014 | Pubmed ID: 24444341
Killer-cell Immunoglobulin-like Receptor gene linkage and copy number variation analysis by droplet digital PCR.
Genome medicine , 2014 | Pubmed ID: 24597950
A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples.
BMC genomics Apr, 2014 | Pubmed ID: 24720548
KIR diversity in Māori and Polynesians: populations in which HLA-B is not a significant KIR ligand.
Immunogenetics Nov, 2014 | Pubmed ID: 25139336
Refinement of the MHC risk map in a scandinavian primary sclerosing cholangitis population.
PloS one , 2014 | Pubmed ID: 25521205
High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis.
Nature genetics Feb, 2015 | Pubmed ID: 25559196
A KIR B centromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2015 | Pubmed ID: 25561558
Surveillance of cell and tissue perturbation by receptors in the LRC.
Immunological reviews Sep, 2015 | Pubmed ID: 26284474
Imputation of KIR Types from SNP Variation Data.
American journal of human genetics Oct, 2015 | Pubmed ID: 26430804
LILRA6 copy number variation correlates with susceptibility to atopic dermatitis.
Immunogenetics 10, 2016 | Pubmed ID: 27333811
Defining KIR and HLA Class I Genotypes at Highest Resolution via High-Throughput Sequencing.
American journal of human genetics Aug, 2016 | Pubmed ID: 27486779
qKAT: a high-throughput qPCR method for KIR gene copy number and haplotype determination.
Genome medicine Sep, 2016 | Pubmed ID: 27686127
Deciphering the killer-cell immunoglobulin-like receptor system at super-resolution for natural killer and T-cell biology.
Immunology 03, 2017 | Pubmed ID: 27779741
Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease.
Nature genetics Feb, 2017 | Pubmed ID: 28067912
Novel KIR genotypes and gene copy number variations in northeastern Thais.
Immunology 03, 2018 | Pubmed ID: 28950036
High-Resolution Genetic and Phenotypic Analysis of KIR2DL1 Alleles and Their Association with Pre-Eclampsia.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2018 | Pubmed ID: 30249807
Report from the Killer-cell Immunoglobulin-like Receptors (KIR) component of the 17th International HLA and Immunogenetics Workshop.
Human immunology Dec, 2018 | Pubmed ID: 30321631
A novel antibody combination to identify KIR2DS2 natural killer cells in KIR2DL3/L2/S2 heterozygous donors.
HLA Jan, 2019 | Pubmed ID: 30381896
Inhibitory killer cell immunoglobulin-like receptors strengthen CD8 T cell-mediated control of HIV-1, HCV, and HTLV-1.
Science immunology Nov, 2018 | Pubmed ID: 30413420
Jyothi Jayaraman1,2,3,4,
Vitalina Kirgizova1,
Da Di1,5,
Christopher Johnson1,6,
Wei Jiang1,7,
James A. Traherne1
1Department of Pathology, University of Cambridge,
2Department of Physiology, Development and Neuroscience, University of Cambridge,
3Department of Obstetrics and Gynaecology, University of Cambridge School of Medicine, NIHR Cambridge Biomedical Research Centre,
4Centre for Trophoblast Research, University of Cambridge,
5Department of Genetics & Evolution, University of Geneva,
6, Royal Papworth Hospital,
7Department of Plant Sciences, University of Cambridge
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