Yifan Cheng

The crystal structure of the bifunctional primase-helicase of bacteriophage T7.

Structure of the human transferrin receptor-transferrin complex.

A chimeric protein of simian immunodeficiency virus envelope glycoprotein gp140 and Escherichia coli aspartate transcarbamoylase.

Negative Staining and Image Classification - Powerful Tools in Modern Electron Microscopy.

Aquaporin-0 membrane junctions reveal the structure of a closed water pore.

Aquaporin-0 membrane junctions form upon proteolytic cleavage.

Molecular model for a complete clathrin lattice from electron cryomicroscopy.

Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating.

Structure and different conformational states of native AMPA receptor complexes.

Lipid-protein interactions in double-layered two-dimensional AQP0 crystals.

ATP binding to PAN or the 26S ATPases causes association with the 20S proteasome, gate opening, and translocation of unfolded proteins.

Single particle reconstructions of the transferrin-transferrin receptor complex obtained with different specimen preparation techniques.

Single particle reconstruction of the human apo-transferrin-transferrin receptor complex.

Three-dimensional structure of an AMPA receptor without associated stargazin/TARP proteins.

Structure determination of clathrin coats to subnanometer resolution by single particle cryo-electron microscopy.

Electron tomography of swollen rigor fibers of insect flight muscle reveals a short and variably angled S2 domain.

Activation of leukocyte beta2 integrins by conversion from bent to extended conformations.

Cryo-electron tomography of clathrin-coated vesicles: structural implications for coat assembly.

Reconstructing the endocytotic machinery.

Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entry.

Structural organization of the anaphase-promoting complex bound to the mitotic activator Slp1.

Polymorphic assemblies and crystalline arrays of lens tetraspanin MP20.

In vitro self-assembly of tailorable nanotubes from a simple protein building block.

A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies.

Mechanism of gate opening in the 20S proteasome by the proteasomal ATPases.

Toward an atomic model of the 26S proteasome.

A designed angiopoietin-2 variant, pentameric COMP-Ang2, strongly activates Tie2 receptor and stimulates angiogenesis.

The advent of near-atomic resolution in single-particle electron microscopy.

Evaluation of imaging plates as recording medium for images of negatively stained single particles and electron diffraction patterns of two-dimensional crystals.

HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells.

Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome-ATPase interactions.

The chromatin remodeller ACF acts as a dimeric motor to space nucleosomes.

GPU-enabled FREALIGN: accelerating single particle 3D reconstruction and refinement in Fourier space on graphics processors.

HIV Rev response element (RRE) directs assembly of the Rev homooligomer into discrete asymmetric complexes.

Structure characterization of the 26S proteasome.

Collecting electron crystallographic data of two-dimensional protein crystals.

Self-aligning amelogenin nanoribbons in oil-water system.

Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein.

A distributed multi-GPU system for high speed electron microscopic tomographic reconstruction.

Estrogen, neuroprotection and neurogenesis after ischemic stroke.

Self-assembly of amelogenin proteins at the water-oil interface.