Simon Andrews

The PX domain: a new phosphoinositide-binding module.

P-Rex2, a new guanine-nucleotide exchange factor for Rac.

TRP channels at a glance.

Regulation of P-Rex1 by phosphatidylinositol (3,4,5)-trisphosphate and Gbetagamma subunits.

P-Rex1 regulates neutrophil function.

ARAP3 is essential for formation of lamellipodia after growth factor stimulation.

PI(3)Kgamma has an important context-dependent role in neutrophil chemokinesis.

PI3K class IB pathway.

PI3K class IB pathway in neutrophils.

P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination.

Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes.

Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells.

Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency.

Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia.

Difference Tracker: ImageJ plugins for fully automated analysis of multiple axonal transport parameters.

What is the advantage of a transient precursor in autophagosome biogenesis?

PI3K signaling through the dual GTPase-activating protein ARAP3 is essential for developmental angiogenesis.

Dynamic stage-specific changes in imprinted differentially methylated regions during early mammalian development and prevalence of non-CpG methylation in oocytes.

Large scale loss of data in low-diversity illumina sequencing libraries can be recovered by deferred cluster calling.

Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation.

Age-dependent axonal transport and locomotor changes and tau hypophosphorylation in a "P301L" tau knockin mouse.

Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications.

Dynamic CpG island methylation landscape in oocytes and preimplantation embryos.

High-throughput analysis of calcium signalling kinetics in astrocytes stimulated with different neurotransmitters.

DNA methylome analysis using short bisulfite sequencing data.

An unbiased assessment of the role of imprinted genes in an intergenerational model of developmental programming.

DNA methylation profiles define stem cell identity and reveal a tight embryonic-extraembryonic lineage boundary.

Mutual antagonism between IP(3)RII and miRNA-133a regulates calcium signals and cardiac hypertrophy.

The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells.

Deficiency in spliceosome-associated factor CTNNBL1 does not affect ongoing cell cycling but delays exit from quiescence and results in embryonic lethality in mice.

FGF Signaling Inhibition in ESCs Drives Rapid Genome-wide Demethylation to the Epigenetic Ground State of Pluripotency.

A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation.

Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity.

Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C.

The miR-155-PU.1 axis acts on Pax5 to enable efficient terminal B cell differentiation.

Epigenetic memory of the first cell fate decision prevents complete ES cell reprogramming into trophoblast.

Global reorganization of the nuclear landscape in senescent cells.

The RNA-binding protein HuR is essential for the B cell antibody response.

The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements.

Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C.

Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome.

ACF chromatin-remodeling complex mediates stress-induced depressive-like behavior.

Deep sequencing and de novo assembly of the mouse oocyte transcriptome define the contribution of transcription to the DNA methylation landscape.

Molecular signatures of plastic phenotypes in two eusocial insect species with simple societies.

Localizing the lipid products of PI3Kγ in neutrophils.

Erratum to: Deep sequencing and de novo assembly of the mouse occyte transcriptome define the contribution of transcription to the DNA methylation landscape.

Ageing is associated with molecular signatures of inflammation and type 2 diabetes in rat pancreatic islets.

Pervasive polymorphic imprinted methylation in the human placenta.

HiCUP: pipeline for mapping and processing Hi-C data.

RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence.

Two Mutually Exclusive Local Chromatin States Drive Efficient V(D)J Recombination.

SNPsplit: Allele-specific splitting of alignments between genomes with known SNP genotypes.

MYC activation and BCL2L11 silencing by a tumour virus through the large-scale reconfiguration of enhancer-promoter hubs.

Comparative Principles of DNA Methylation Reprogramming during Human and Mouse In Vitro Primordial Germ Cell Specification.

Deletion of the Polycomb-Group Protein EZH2 Leads to Compromised Self-Renewal and Differentiation Defects in Human Embryonic Stem Cells.

DNA methylation and gene expression changes derived from assisted reproductive technologies can be decreased by reproductive fluids.

Gender Differences in Global but Not Targeted Demethylation in iPSC Reprogramming.

Cluster Flow: A user-friendly bioinformatics workflow tool.

Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism.

Transcription and chromatin determinants of de novo DNA methylation timing in oocytes.

An endosiRNA-Based Repression Mechanism Counteracts Transposon Activation during Global DNA Demethylation in Embryonic Stem Cells.

Local Chromatin Features Including PU.1 and IKAROS Binding and H3K4 Methylation Shape the Repertoire of Immunoglobulin Kappa Genes Chosen for V(D)J Recombination.

MLL2 conveys transcription-independent H3K4 trimethylation in oocytes.

Capture Hi-C identifies putative target genes at 33 breast cancer risk loci.

Comparison of whole-genome bisulfite sequencing library preparation strategies identifies sources of biases affecting DNA methylation data.

TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD.

Unbiased quantification of immunoglobulin diversity at the DNA level with VDJ-seq.

Publisher Correction: TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD.

FastQ Screen: A tool for multi-genome mapping and quality control.

Correction to: Comparison of whole-genome bisulfite sequencing library preparation strategies identifies sources of biases affecting DNA methylation data.

MicroRNA-155 is essential for the optimal proliferation and survival of plasmablast B cells.

RNA proximity sequencing reveals the spatial organization of the transcriptome in the nucleus.

Ageing affects DNA methylation drift and transcriptional cell-to-cell variability in mouse muscle stem cells.

Endogenous retroviral insertions drive non-canonical imprinting in extra-embryonic tissues.

BNC1 regulates cell heterogeneity in human pluripotent stem cell-derived epicardium.

A KHDC3L mutation resulting in recurrent hydatidiform mole causes genome-wide DNA methylation loss in oocytes and persistent imprinting defects post-fertilisation.

RNA proximity sequencing data and analysis pipeline from a human neuroblastoma nuclear transcriptome.

Low rates of mutation in clinical grade human pluripotent stem cells under different culture conditions.

DNA methylation changes during preimplantation development reveal inter-species differences and reprogramming events at imprinted genes.