Department of Pharmacology and Physiology
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The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling.
Proceedings of the National Academy of Sciences of the United States of America May, 2002 | Pubmed ID: 12011466
The chemokine receptor CXCR4 regulates cell-cycle proteins in neurons.
Journal of neurovirology Jun, 2003 | Pubmed ID: 12775414
Regulation of cell cycle proteins by chemokine receptors: A novel pathway in human immunodeficiency virus neuropathogenesis?
Journal of neurovirology , 2004 | Pubmed ID: 14982748
CX3CR1-fractalkine expression regulates cellular mechanisms involved in adhesion, migration, and survival of human prostate cancer cells.
Cancer research Jul, 2004 | Pubmed ID: 15256432
Apoptotic and antiapoptotic effects of CXCR4: is it a matter of intrinsic efficacy? Implications for HIV neuropathogenesis.
AIDS research and human retroviruses Oct, 2004 | Pubmed ID: 15585097
Regulation of neuronal P53 activity by CXCR 4.
Molecular and cellular neurosciences Sep, 2005 | Pubmed ID: 16005638
Bone-metastatic potential of human prostate cancer cells correlates with Akt/PKB activation by alpha platelet-derived growth factor receptor.
Oncogene Oct, 2005 | Pubmed ID: 16007172
Human immunodeficiency virus gp120-induced apoptosis of human neuroblastoma cells in the absence of CXCR4 internalization.
Journal of neurovirology Jun, 2006 | Pubmed ID: 16877302
Role of the transcription factor E2F1 in CXCR4-mediated neurotoxicity and HIV neuropathology.
Neurobiology of disease Jan, 2007 | Pubmed ID: 17011204
Modulation of neuronal CXCR4 by the micro-opioid agonist DAMGO.
Journal of neurovirology Dec, 2006 | Pubmed ID: 17162664
Modulation of dendritic cell maturation and function by the Tax protein of human T cell leukemia virus type 1.
Journal of leukocyte biology Jul, 2007 | Pubmed ID: 17442856
GTPgammaS incorporation in the rat brain: a study on mu-opioid receptors and CXCR4.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology Mar, 2008 | Pubmed ID: 18247130
CX3CR1 is expressed by prostate epithelial cells and androgens regulate the levels of CX3CL1/fractalkine in the bone marrow: potential role in prostate cancer bone tropism.
Cancer research Mar, 2008 | Pubmed ID: 18339851
Morphine increases brain levels of ferritin heavy chain leading to inhibition of CXCR4-mediated survival signaling in neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2009 | Pubmed ID: 19244528
Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling.
The Journal of biological chemistry Mar, 2010 | Pubmed ID: 20048153
Interactions between chemokines: regulation of fractalkine/CX3CL1 homeostasis by SDF/CXCL12 in cortical neurons.
The Journal of biological chemistry Apr, 2010 | Pubmed ID: 20124406
CXCL12-mediated regulation of ANP32A/Lanp, a component of the inhibitor of histone acetyl transferase (INHAT) complex, in cortical neurons.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology Mar, 2011 | Pubmed ID: 20617464
Disruption of neuronal CXCR4 function by opioids: preliminary evidence of ferritin heavy chain as a potential etiological agent in neuroAIDS.
Journal of neuroimmunology Jul, 2010 | Pubmed ID: 20627326
Alterations of CXCR4 function in μ-opioid receptor-deficient glia.
The European journal of neuroscience Oct, 2010 | Pubmed ID: 20880358
Regulation of neuronal ferritin heavy chain, a new player in opiate-induced chemokine dysfunction.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology Dec, 2011 | Pubmed ID: 21465240
CXCR7 protein expression in human adult brain and differentiated neurons.
PloS one , 2011 | Pubmed ID: 21655198
Role of mu-opioids as cofactors in human immunodeficiency virus type 1 disease progression and neuropathogenesis.
Journal of neurovirology Aug, 2011 | Pubmed ID: 21735315
The chemokine receptor CX3CR1 is directly involved in the arrest of breast cancer cells to the skeleton.
Breast cancer research : BCR Sep, 2011 | Pubmed ID: 21933397
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