Simon M. Petersen-Jones

An improved DNA-based test for detection of the codon 616 mutation in the alpha cyclic GMP phosphodiesterase gene that causes progressive retinal atrophy in the Cardigan Welsh Corgi.

Detailed histopathologic characterization of the retinopathy, globe enlarged (rge) chick phenotype.

Assessment of the dark-adaptation time required for recovery of electroretinographic responses in dogs after fundus photography and indirect ophthalmoscopy.

Influence of recording electrode type and reference electrode position on the canine electroretinogram.

Postnatal development of canine axial globe length measured by B-scan ultrasonography.

Electroretinographic features of the retinopathy, globe enlarged (rge) chick phenotype.

Ocular melanosis in the Cairn Terrier: clinical description and investigation of mode of inheritance.

Ocular melanosis in the Cairn Terrier: histopathological description of the condition, and immunohistological and ultrastructural characterization of the characteristic pigment-laden cells.

A novel method for objective vision testing in canine models of inherited retinal disease.

Characterization of a canine model of autosomal recessive retinitis pigmentosa due to a PDE6A mutation.

Topographical characterization of cone photoreceptors and the area centralis of the canine retina.

AAV retinal transduction in a large animal model species: comparison of a self-complementary AAV2/5 with a single-stranded AAV2/5 vector.

Improvement of visual performance with intravitreal administration of 9-cis-retinal in Rpe65-mutant dogs.

Gene augmentation trials using the Rpe65-deficient dog: contributions towards development and refinement of human clinical trials.

Bilateral uveal metastasis of a subcutaneous fibrosarcoma in a cat.

Viral vectors for targeting the canine retina: a review.

A facemask for gaseous anesthesia in laboratory rodents and chicks that allows easy access to the eyes for ophthalmic procedures.

Exclusion of eleven candidate genes for ocular melanosis in Cairn terriers.

Evaluation of lateral spread of transgene expression following subretinal AAV-mediated gene delivery in dogs.

A large animal model for CNGB1 autosomal recessive retinitis pigmentosa.

Successful gene therapy in older Rpe65-deficient dogs following subretinal injection of an adeno-associated vector expressing RPE65.

A partial gene deletion of SLC45A2 causes oculocutaneous albinism in Doberman pinscher dogs.

Altered fundus appearance resulting from autofluorescence imaging with the confocal scanning laser ophthalmoscope (cSLO) in cats.

Isolation and cultivation of canine uveal melanocytes.

Dog models for blinding inherited retinal dystrophies.

Long-term effect of gene therapy on Leber's congenital amaurosis.

Progressive retinal atrophy in the Polski Owczarek Nizinny dog: a clinical and genetic study.

Sudden acquired retinal degeneration syndrome (SARDS) - a review and proposed strategies toward a better understanding of pathogenesis, early diagnosis, and therapy.

Genetics of Canine Primary Glaucomas.

An association between systemic cyclosporine administration and development of acute bullous keratopathy in cats.

A tool set to allow rapid screening of dog families with PRA for association with candidate genes.

CrxRdy Cat: A Large Animal Model for CRX-Associated Leber Congenital Amaurosis.

Assessment of Rod, Cone, and Intrinsically Photosensitive Retinal Ganglion Cell Contributions to the Canine Chromatic Pupillary Response.

Early-Onset Progressive Degeneration of the Area Centralis in RPE65-Deficient Dogs.

Birth of clones of the world's first cloned dog.

Patients and animal models of CNGβ1-deficient retinitis pigmentosa support gene augmentation approach.

Gene Supplementation Rescues Rod Function and Preserves Photoreceptor and Retinal Morphology in Dogs, Leading the Way Toward Treating Human -Retinitis Pigmentosa.

Retinal-chitosan Conjugates Effectively Deliver Active Chromophores to Retinal Photoreceptor Cells in Blind Mice and Dogs.

Physiological characterization of ocular melanosis-affected canine melanocytes.

CORRELATIONS BETWEEN EXPERIMENTAL MYOPIA MODELS AND HUMAN PATHOLOGIC MYOPIA.

Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in the Subretinal Space of the Cat Eye.

Advancing Gene Therapy for PDE6A Retinitis Pigmentosa.

Sildenafil Administration in Dogs Heterozygous for a Functional Null Mutation in Pde6a: Suppressed Rod-Mediated ERG Responses and Apparent Retinal Outer Nuclear Layer Thinning.

Development of a protocol for maintaining viability while shipping organoid-derived retinal tissue.

A review of electroretinography waveforms and models and their application in the dog.

Large Animal Models of Inherited Retinal Degenerations: A Review.

Mutations in the Kinesin-2 Motor KIF3B Cause an Autosomal-Dominant Ciliopathy.

Changes in retinal layer thickness with maturation in the dog: an in vivo spectral domain - optical coherence tomography imaging study.

A novel mutation in PDE6B in Spanish Water Dogs with early-onset progressive retinal atrophy.

Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium.

Pluripotent Stem Cell-Based Organoid Technologies for Developing Next-Generation Vision Restoration Therapies of Blindness.

A Missense Variant Is Associated with Canine Laryngeal Paralysis and Polyneuropathy.

A Comprehensive Study of the Retinal Phenotype of Rpe65-Deficient Dogs.

Novel AAV capsids for intravitreal gene therapy of photoreceptor disorders.

Comparison of Developmental Dynamics in Human Fetal Retina and Human Pluripotent Stem Cell-Derived Retinal Tissue.

ERG assessment of altered retinal function in canine models of retinitis pigmentosa and monitoring of response to translatable gene augmentation therapy.

CNGB1-related rod-cone dystrophy: A mutation review and update.