Koenraad Philippaert

Insulin downregulates the expression of the Ca2+-activated nonselective cation channel TRPM5 in pancreatic islets from leptin-deficient mouse models.

Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity.

Bax inhibitor-1 deficiency leads to obesity by increasing Ca-dependent insulin secretion.

Vitamin D is an endogenous partial agonist of the transient receptor potential vanilloid 1 channel.