Branden S. Moriarity

Efficient non-viral integration and stable gene expression in multipotent adult progenitor cells.

Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR.

Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST.

Modular assembly of transposon integratable multigene vectors using RecWay assembly.

Canonical Wnt/β-catenin signaling drives human schwann cell transformation, progression, and tumor maintenance.

Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis.

Simple and efficient methods for enrichment and isolation of endonuclease modified cells.

Trp53 haploinsufficiency modifies EGFR-driven peripheral nerve sheath tumorigenesis.

HomeRun Vector Assembly System: a flexible and standardized cloning system for assembly of multi-modular DNA constructs.

PVT1 dependence in cancer with MYC copy-number increase.

Using RNA-seq and targeted nucleases to identify mechanisms of drug resistance in acute myeloid leukemia.

A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis.

Sleeping Beauty transposon insertional mutagenesis based mouse models for cancer gene discovery.

A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma.

RNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens.

Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma.

Coping with cancer genes altered by copy number.

mTORC1 Coordinates Protein Synthesis and Immunoproteasome Formation via PRAS40 to Prevent Accumulation of Protein Stress.

RALB provides critical survival signals downstream of Ras in acute myeloid leukemia.

Using genome-wide CRISPR library screening with library resistant DCK to find new sources of Ara-C drug resistance in AML.

Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma.

Relative importance of β- and γ-actin in primary mouse embryonic fibroblasts.

Prosurvival long noncoding RNA regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3.

Rapid generation of Col7a1 mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells.

A novel role for SALL4 during scar-free wound healing in axolotl.

Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma.

CRISPR/Cas9 library screening for drug target discovery.

Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity.

Engineering of Primary Human B cells with CRISPR/Cas9 Targeted Nuclease.

The Molecular Imaging of Natural Killer Cells.

Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays.

Screen Identifies and Other Genetic Drivers in Human B-cell Lymphoma.

Cancer Gene Discovery Utilizing Sleeping Beauty Transposon Mutagenesis.

Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors.

Identification of candidate neoantigens produced by fusion transcripts in human osteosarcomas.

HBx-K130M/V131I Promotes Liver Cancer in Transgenic Mice via AKT/FOXO1 Signaling Pathway and Arachidonic Acid Metabolism.

EditR: A Method to Quantify Base Editing from Sanger Sequencing.

Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis.

SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis.

A Genetically Engineered Primary Human Natural Killer Cell Platform for Cancer Immunotherapy.

Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors.

Author Correction: Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors.

CRISPR/Cas9-Mediated Genome Engineering of Primary Human B Cells.

PLX3397 treatment inhibits constitutive CSF1R-induced oncogenic ERK signaling, reduces tumor growth, and metastatic burden in osteosarcoma.

Efficient targeted integration directed by short homology in zebrafish and mammalian cells.

C-to-U RNA Editing: From Computational Detection to Experimental Validation.

Implication of ZNF217 in accelerating tumor development and therapeutically targeting ZNF217-induced PI3K-AKT signaling for the treatment of metastatic osteosarcoma.

The S-phase-induced lncRNA promotes cell proliferation by controlling YAP1/Hippo signaling pathway.