Krembil Research Institute,
Toronto Western Hospital,
Krembil Research Institute, Toronto Western Hospital
Suneil K. Kalia has not added Biography.
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BAG5 inhibits parkin and enhances dopaminergic neuron degeneration.
Neuron Dec, 2004 | Pubmed ID: 15603737
NMDA receptors in clinical neurology: excitatory times ahead.
The Lancet. Neurology Aug, 2008 | Pubmed ID: 18635022
Ubiquitinylation of α-synuclein by carboxyl terminus Hsp70-interacting protein (CHIP) is regulated by Bcl-2-associated athanogene 5 (BAG5).
PloS one Feb, 2011 | Pubmed ID: 21358815
Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2014 | Pubmed ID: 24510904
α-Synuclein and Lewy pathology in Parkinson's disease.
Current opinion in neurology Aug, 2015 | Pubmed ID: 26110807
Disease-modifying strategies for Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society Sep, 2015 | Pubmed ID: 26208210
Rapid Modulation of Protein Expression in the Rat Hippocampus Following Deep Brain Stimulation of the Fornix.
Brain stimulation Nov-Dec, 2015 | Pubmed ID: 26321354
Merging DBS with viral vector or stem cell implantation: "hybrid" stereotactic surgery as an evolution in the surgical treatment of Parkinson's disease.
Molecular therapy. Methods & clinical development , 2016 | Pubmed ID: 26817024
Deep Brain Stimulation Target Selection for Parkinson's Disease.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques Jan, 2017 | Pubmed ID: 26976064
Subdural Collection as Initial Presentation of Granulomatosis With Polyangiitis.
JAMA neurology 05, 2016 | Pubmed ID: 26998710
Patient Perspectives Regarding Ethics of Spinal Column Stimulators in the Surgical Management of Persistent Postoperative Neuropathic Pain.
Neuromodulation : journal of the International Neuromodulation Society Apr, 2017 | Pubmed ID: 27491346
Deep Brain Stimulation in Rare Inherited Dystonias.
Brain stimulation Nov - Dec, 2016 | Pubmed ID: 27743838
Anesthesia considerations for patients with an implanted deep brain stimulator undergoing surgery: a review and update.
Canadian journal of anaesthesia = Journal canadien d'anesthesie Mar, 2017 | Pubmed ID: 28028671
In reply: Parkinsonism-hyperthermia syndrome and deep brain stimulation.
Canadian journal of anaesthesia = Journal canadien d'anesthesie 06, 2017 | Pubmed ID: 28197981
Chaperone-Based Therapies for Disease Modification in Parkinson's Disease.
Parkinson's disease , 2017 | Pubmed ID: 28913005
Neuronal inhibition and synaptic plasticity of basal ganglia neurons in Parkinson's disease.
Brain : a journal of neurology 01, 2018 | Pubmed ID: 29236966
Pallidal deep brain stimulation modulates cortical excitability and plasticity.
Annals of neurology Feb, 2018 | Pubmed ID: 29369401
Is there a role for MR-guided focused ultrasound in Parkinson's disease?
Movement disorders : official journal of the Movement Disorder Society 04, 2018 | Pubmed ID: 29476631
Emerging disease-modifying strategies targeting α-synuclein for the treatment of Parkinson's disease.
British journal of pharmacology 08, 2018 | Pubmed ID: 29722028
Physiological mechanisms of thalamic ventral intermediate nucleus stimulation for tremor suppression.
Brain : a journal of neurology 07, 2018 | Pubmed ID: 29878147
Event-related deep brain stimulation of the subthalamic nucleus affects conflict processing.
Annals of neurology 10, 2018 | Pubmed ID: 30152889
Low-intensity ultrasound neuromodulation: An overview of mechanisms and emerging human applications.
Brain stimulation Nov - Dec, 2018 | Pubmed ID: 30166265
Modulation of inhibitory plasticity in basal ganglia output nuclei of patients with Parkinson's disease.
Neurobiology of disease 04, 2019 | Pubmed ID: 30391540
Parkinsonism due to A53E α-synuclein gene mutation: Clinical, genetic, epigenetic, and biochemical features.
Movement disorders : official journal of the Movement Disorder Society 12, 2018 | Pubmed ID: 30423204
Ultra-high-frequency deep brain stimulation at 10,000 Hz improves motor function.
Movement disorders : official journal of the Movement Disorder Society 01, 2019 | Pubmed ID: 30423217
A systematic review of deep brain stimulation for the treatment of drug-resistant epilepsy in childhood.
Journal of neurosurgery. Pediatrics 11, 2018 | Pubmed ID: 30544364
On the (Non-)equivalency of monopolar and bipolar settings for deep brain stimulation fMRI studies of Parkinson's disease patients.
Journal of magnetic resonance imaging : JMRI 06, 2019 | Pubmed ID: 30552842
Deep brain stimulation: potential for neuroprotection.
Annals of clinical and translational neurology 01, 2019 | Pubmed ID: 30656196
Deep Brain Stimulation Rescues Memory and Synaptic Activity in a Rat Model of Global Ischemia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 03, 2019 | Pubmed ID: 30696731
A Primer on Magnetic Resonance-Guided Laser Interstitial Thermal Therapy for Medically Refractory Epilepsy.
Journal of Korean Neurosurgical Society May, 2019 | Pubmed ID: 31085962
Functional MRI Safety and Artifacts during Deep Brain Stimulation: Experience in 102 Patients.
Radiology 10, 2019 | Pubmed ID: 31385756
Case Studies in Neuroscience: Lack of inhibitory synaptic plasticity in the substantia nigra pars reticulata of a patient with lithium-induced tremor.
Journal of neurophysiology 10, 2019 | Pubmed ID: 31411948
Aggressiveness after centromedian nucleus stimulation engages prefrontal thalamocortical circuitry.
Brain stimulation Mar - Apr, 2020 | Pubmed ID: 31727583
Bcl-2-associated athanogene 5 (BAG5) regulates Parkin-dependent mitophagy and cell death.
Cell death & disease 12, 2019 | Pubmed ID: 31787745
Safety assessment of spine MRI in deep brain stimulation patients.
Journal of neurosurgery. Spine Feb, 2020 | Pubmed ID: 32059193
Early-onset impairment of the ubiquitin-proteasome system in dopaminergic neurons caused by α-synuclein.
Acta neuropathologica communications 02, 2020 | Pubmed ID: 32059750
Methods for detecting toxic α-synuclein species as a biomarker for Parkinson's disease.
Critical reviews in clinical laboratory sciences 08, 2020 | Pubmed ID: 32116096
Neuronal Activity and Synaptic Plasticity in a Reimplanted STN-DBS Patient with Parkinson's Disease: Recordings from Two Surgeries.
Stereotactic and functional neurosurgery , 2020 | Pubmed ID: 32294659
Deep Brain Stimulation of the Medial Septal Nucleus Induces Expression of a Virally Delivered Reporter Gene in Dentate Gyrus.
Frontiers in neuroscience , 2020 | Pubmed ID: 32477058
LRRK2 and α-Synuclein: Distinct or Synergistic Players in Parkinson's Disease?
Frontiers in neuroscience , 2020 | Pubmed ID: 32625052
Cost-effectiveness analysis of MR-guided focused ultrasound thalamotomy for tremor-dominant Parkinson's disease.
Journal of neurosurgery Aug, 2020 | Pubmed ID: 32764177
The Child & Youth CompreHensIve Longitudinal Database for Deep Brain Stimulation (CHILD-DBS).
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery Feb, 2021 | Pubmed ID: 32935233
Microelectrode Recording and Radiofrequency Thalamotomy following Focused Ultrasound Thalamotomy.
Stereotactic and functional neurosurgery Sep, 2020 | Pubmed ID: 32937628
Regulation of Parkin-dependent mitophagy by Bcl-2-associated athanogene (BAG) family members.
Neural regeneration research Apr, 2021 | Pubmed ID: 33063725
The Association of Dexmedetomidine with Firing Properties in Pallidal Neurons.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques Nov, 2020 | Pubmed ID: 33148354
The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates.
The Journal of biological chemistry Nov, 2020 | Pubmed ID: 33168630
C-terminus of Hsp70 Interacting Protein (CHIP) and Neurodegeneration: Lessons from the Bench and Bedside
Current neuropharmacology 11, 2020 | Pubmed ID: 33200713
Probabilistic Mapping of Deep Brain Stimulation: Insights from 15 Years of Therapy.
Annals of neurology Nov, 2020 | Pubmed ID: 33252146
Mapping efficacious deep brain stimulation for pediatric dystonia.
Journal of neurosurgery. Pediatrics Jan, 2021 | Pubmed ID: 33385998
The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates.
The Journal of biological chemistry Dec, 2020 | Pubmed ID: 33410405
Darren M. O'Hara1,2,
Minesh Kapadia1,2,
Susan Ping1,2,
Suneil K. Kalia1,2,3,
Lorraine V. Kalia1,2,4,5,6
1Krembil Research Institute, Toronto Western Hospital, University Health Network,
2Department of Laboratory Medicine and Pathobiology, University of Toronto,
3Department of Surgery, Division of Neurosurgery, University of Toronto,
4Department of Medicine, Division of Neurology, University of Toronto,
5Department of Medicine, Division of Neurology, Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, University Health Network,
6Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto
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