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Retrovirus-Host Interactions Laboratory
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Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction.
PLoS pathogens Oct, 2015 | Pubmed ID: 26431200
Immune responses to endogenous retroelements: taking the bad with the good.
Nature reviews. Immunology Apr, 2016 | Pubmed ID: 27026073
Expression levels of Fv1: effects on retroviral restriction specificities.
Retrovirology 06, 2016 | Pubmed ID: 27342974
Structure of a Spumaretrovirus Gag Central Domain Reveals an Ancient Retroviral Capsid.
PLoS pathogens Nov, 2016 | Pubmed ID: 27829070
Eleventh International Foamy Virus Conference-Meeting Report.
Viruses 11, 2016 | Pubmed ID: 27886074
SAMHD1 enhances nucleoside-analogue efficacy against HIV-1 in myeloid cells.
Scientific reports 02, 2017 | Pubmed ID: 28220857
Mutation of the Putative Immunosuppressive Domain of the Retroviral Envelope Glycoprotein Compromises Infectivity.
Journal of virology 11, 2017 | Pubmed ID: 28814524
Making a virtue of necessity: the pleiotropic role of human endogenous retroviruses in cancer.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences Oct, 2017 | Pubmed ID: 28893944
Physiological and Pathological Transcriptional Activation of Endogenous Retroelements Assessed by RNA-Sequencing of B Lymphocytes.
Frontiers in microbiology , 2017 | Pubmed ID: 29312197
Ortervirales: New Virus Order Unifying Five Families of Reverse-Transcribing Viruses.
Journal of virology 06, 2018 | Pubmed ID: 29618642
Restoration of Endogenous Retrovirus Infectivity Impacts Mouse Cancer Models.
Cancer immunology research 11, 2018 | Pubmed ID: 30143537
Evolutionary journey of the retroviral restriction gene .
Proceedings of the National Academy of Sciences of the United States of America 10, 2018 | Pubmed ID: 30224488
A helical LC3-interacting region mediates the interaction between the retroviral restriction factor Trim5α and mammalian autophagy-related ATG8 proteins.
The Journal of biological chemistry 11, 2018 | Pubmed ID: 30282803
Positive selection in dNTPase SAMHD1 throughout mammalian evolution.
Proceedings of the National Academy of Sciences of the United States of America 09, 2019 | Pubmed ID: 31451672
LTR retroelement expansion of the human cancer transcriptome and immunopeptidome revealed by de novo transcript assembly.
Genome research 10, 2019 | Pubmed ID: 31537638
Structural basis for Fullerene geometry in a human endogenous retrovirus capsid.
Nature communications 12, 2019 | Pubmed ID: 31862888
Structure of ARC1 reveals a repurposed molecule with characteristics of retroviral Gag.
Science advances 01, 2020 | Pubmed ID: 31911950
Antibody-induced internalisation of retroviral envelope glycoproteins is a signal initiation event.
PLoS pathogens 05, 2020 | Pubmed ID: 32453763
Duplication and divergence of the retrovirus restriction gene Fv1 in Mus caroli allows protection from multiple retroviruses.
PLoS genetics 06, 2020 | Pubmed ID: 32525879
Gv1, a Zinc Finger Gene Controlling Endogenous MLV Expression.
Molecular biology and evolution May, 2021 | Pubmed ID: 33560369
The Francis Crick Institute
Paula Ordonez1,
Kate N. Bishop2,
Jonathan P. Stoye1,
Harriet Cordelia Theed Groom3
1Retrovirus-Host Interactions Laboratory, The Francis Crick Institute,
2Retroviral Replication Laboratory, The Francis Crick Institute,
3Sidney Sussex College, Department of Medicine, University of Cambridge
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