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Department of Biology
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Sphingosine kinase: a closer look at last.
Structure (London, England : 1993) May, 2013 | Pubmed ID: 23664359
A real-time high-throughput fluorescence assay for sphingosine kinases.
Journal of lipid research 07, 2014 | Pubmed ID: 24792926
Role of sphingosine kinase 1 and sphingosine-1-phosphate in CD40 signaling and IgE class switching.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Oct, 2014 | Pubmed ID: 25002116
Revisiting the sphingolipid rheostat: Evolving concepts in cancer therapy.
Experimental cell research May, 2015 | Pubmed ID: 25770011
Sphingosine and Sphingosine Kinase 1 Involvement in Endocytic Membrane Trafficking.
The Journal of biological chemistry 02, 2017 | Pubmed ID: 28049734
An integrative study to identify novel scaffolds for sphingosine kinase 1 inhibitors.
European journal of medicinal chemistry Oct, 2017 | Pubmed ID: 28822281
TP53 is required for BECN1- and ATG5-dependent cell death induced by sphingosine kinase 1 inhibition.
Autophagy , 2018 | Pubmed ID: 29368980
ABCC1-Exported Sphingosine-1-phosphate, Produced by Sphingosine Kinase 1, Shortens Survival of Mice and Patients with Breast Cancer.
Molecular cancer research : MCR Jun, 2018 | Pubmed ID: 29523764
Differential Radiation Sensitivity in p53 Wild-Type and p53-Deficient Tumor Cells Associated with Senescence but not Apoptosis or (Nonprotective) Autophagy.
Radiation research 11, 2018 | Pubmed ID: 30132722
Synthesis and biological evaluation of sphingosine kinase 2 inhibitors with anti-inflammatory activity.
Archiv der Pharmazie Mar, 2019 | Pubmed ID: 30648282
Design of new quinolin-2-one-pyrimidine hybrids as sphingosine kinases inhibitors.
Bioorganic chemistry 01, 2020 | Pubmed ID: 31757412
Influence of nonprotective autophagy and the autophagic switch on sensitivity to cisplatin in non-small cell lung cancer cells.
Biochemical pharmacology 05, 2020 | Pubmed ID: 32135156
A simple method for sphingolipid analysis of tissues embedded in optimal cutting temperature compound.
Journal of lipid research 06, 2020 | Pubmed ID: 32341007
Targeting defective sphingosine kinase 1 in Niemann-Pick type C disease with an activator mitigates cholesterol accumulation.
The Journal of biological chemistry 07, 2020 | Pubmed ID: 32385114
Virginia Commonwealth University
Massey Cancer Center
April E. Boyd1,
Jeremy Allegood2,
Santiago Lima1,3
1Department of Biology, Virginia Commonwealth University,
2VCU Lipidomics/Metabolomics Shared Resource, Virginia Commonwealth University School of Medicine,
3, Massey Cancer Center
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