Julien Roche

Evolution under Drug Pressure Remodels the Folding Free-Energy Landscape of Mature HIV-1 Protease.

Insights into the Conformation of the Membrane Proximal Regions Critical to the Trimerization of the HIV-1 gp41 Ectodomain Bound to Dodecyl Phosphocholine Micelles.

Structural Studies of a Rationally Selected Multi-Drug Resistant HIV-1 Protease Reveal Synergistic Effect of Distal Mutations on Flap Dynamics.

High-pressure NMR techniques for the study of protein dynamics, folding and aggregation.

Prediction of nearest neighbor effects on backbone torsion angles and NMR scalar coupling constants in disordered proteins.

Monitoring protein folding through high pressure NMR spectroscopy.

Pushing the Limits of Structure-Based Models: Prediction of Nonglobular Protein Folding and Fibrils Formation with Go-Model Simulations.

Lessons from pressure denaturation of proteins.

Exploring Protein Conformational Landscapes Using High-Pressure NMR.

ScanFold: an approach for genome-wide discovery of local RNA structural elements-applications to Zika virus and HIV.

Local unfolding of the HSP27 monomer regulates chaperone activity.

Disorder Mediated Oligomerization of Proteins Revealed by Coarse-Grained Molecular Dynamics Simulations.

Thermodynamic stability of hnRNP A1 low complexity domain revealed by high-pressure NMR.

Structure elucidation of the elusive Enzyme I monomer reveals the molecular mechanisms linking oligomerization and enzymatic activity.