Paul Schedl

First seduction, then transfiguration.

Masters change, slaves remain.

Protein:protein interactions and the pairing of boundary elements in vivo.

Making good neighbors: the right fence for the right job.

Functional conservation of the sex-lethal sex determining promoter, Sxl-Pe, in Drosophila virilis.

A conserved chromatin architecture marks and maintains the restricted germ cell lineage in worms and flies.

Overlapping mechanisms function to establish transcriptional quiescence in the embryonic Drosophila germline.

The Drosophila GAGA factor is required for dosage compensation in males and for the formation of the male-specific-lethal complex chromatin entry site at 12DE.

Developmental modulation of Fab-7 boundary function.

Characterization of the grappa gene, the Drosophila histone H3 lysine 79 methyltransferase.

The enhancer-blocking activity of the Fab-7 boundary from the Drosophila bithorax complex requires GAGA-factor-binding sites.

The Drosophila fragile X protein functions as a negative regulator in the orb autoregulatory pathway.

Nanos downregulates transcription and modulates CTD phosphorylation in the soma of early Drosophila embryos.

Drosophila argonaute-2 is required early in embryogenesis for the assembly of centric/centromeric heterochromatin, nuclear division, nuclear migration, and germ-cell formation.

HMGCoA reductase potentiates hedgehog signaling in Drosophila melanogaster.

The drosophila fragile X protein dFMR1 is required during early embryogenesis for pole cell formation and rapid nuclear division cycles.

Architecture of a polycomb nucleoprotein complex.

The master switch gene sex-lethal promotes female development by negatively regulating the N-signaling pathway.

toutvelu, a regulator of heparan sulfate proteoglycan biosynthesis, controls guidance cues for germ-cell migration.

A stage-specific factor confers Fab-7 boundary activity during early embryogenesis in Drosophila.

Enhancer blocking and transvection at the Drosophila apterous locus.

Functioning of the Drosophila Wilms'-tumor-1-associated protein homolog, Fl(2)d, in Sex-lethal-dependent alternative splicing.

The Toll-->NFkappaB signaling pathway mediates the neuropathological effects of the human Alzheimer's Abeta42 polypeptide in Drosophila.

Ggamma1, a downstream target for the hmgcr-isoprenoid biosynthetic pathway, is required for releasing the Hedgehog ligand and directing germ cell migration.

Hrp48 attenuates Sxl expression to allow for proper notch expression and signaling in wing development.

Mechanism of chromosomal boundary action: roadblock, sink, or loop?

The Drosophila Myc gene, diminutive, is a positive regulator of the Sex-lethal establishment promoter, Sxl-Pe.

The translation initiation factor eIF4E regulates the sex-specific expression of the master switch gene Sxl in Drosophila melanogaster.

The Drosophila CPEB protein Orb2 has a novel expression pattern and is important for asymmetric cell division and nervous system function.

The functioning of the Drosophila CPEB protein Orb is regulated by phosphorylation and requires casein kinase 2 activity.

Single-molecule imaging of transcriptionally coupled and uncoupled splicing.

Theoretical analysis of the role of chromatin interactions in long-range action of enhancers and insulators.

Cup blocks the precocious activation of the orb autoregulatory loop.

The histone H4 lysine 20 monomethyl mark, set by PR-Set7 and stabilized by L(3)mbt, is necessary for proper interphase chromatin organization.

Maintaining sufficient nanos is a critical function for polar granule component in the specification of primordial germ cells.

The CPEB protein Orb2 has multiple functions during spermatogenesis in Drosophila melanogaster.

Elba, a novel developmentally regulated chromatin boundary factor is a hetero-tripartite DNA binding complex.

The hedgehog pathway gene shifted functions together with the hmgcr-dependent isoprenoid biosynthetic pathway to orchestrate germ cell migration.

Rasputin functions as a positive regulator of orb in Drosophila oogenesis.

Bi-functional cross-linking reagents efficiently capture protein-DNA complexes in Drosophila embryos.

Making connections: insulators organize eukaryotic chromosomes into independent cis-regulatory networks.

BMP signaling and the maintenance of primordial germ cell identity in Drosophila embryos.

Spermatid cyst polarization in Drosophila depends upon apkc and the CPEB family translational regulator orb2.

Xenotransplantation exposes the etiology of azoospermia factor (AZF) induced male sterility.

The Drosophila melanogaster Mutants apblot and apXasta Affect an Essential apterous Wing Enhancer.