Division of Medical Sciences
Brian R. Christie has not added Biography.
If you are Brian R. Christie and would like to personalize this page please email our Author Liaison for assistance.
Long-term depression in vivo: effects of sex, stress, diet, and prenatal ethanol exposure.
Hippocampus , 2008 | Pubmed ID: 18240319
Exercising our brains: how physical activity impacts synaptic plasticity in the dentate gyrus.
Neuromolecular medicine , 2008 | Pubmed ID: 18535925
Stress differentially regulates the effects of voluntary exercise on cell proliferation in the dentate gyrus of mice.
Hippocampus Oct, 2009 | Pubmed ID: 18958850
Cognition, learning behaviour and hippocampal synaptic plasticity are not disrupted in mice over-expressing the cholesterol transporter ABCG1.
Lipids in health and disease Feb, 2009 | Pubmed ID: 19239689
Endogenous cannabinoid signaling is required for voluntary exercise-induced enhancement of progenitor cell proliferation in the hippocampus.
Hippocampus Apr, 2010 | Pubmed ID: 19489006
NGF is essential for hippocampal plasticity and learning.
The Journal of neuroscience : the official journal of the Society for Neuroscience Sep, 2009 | Pubmed ID: 19726646
Running reduces stress and enhances cell genesis in aged mice.
Neurobiology of aging Dec, 2011 | Pubmed ID: 20106549
Characterization of the neurogenesis quiescent zone in the rodent brain: effects of age and exercise.
The European journal of neuroscience Mar, 2010 | Pubmed ID: 20374281
Hippocampal cell loss and neurogenesis after fetal alcohol exposure: insights from different rodent models.
Brain research reviews Sep, 2010 | Pubmed ID: 20471420
Altered adult hippocampal neurogenesis in the YAC128 transgenic mouse model of Huntington disease.
Neurobiology of disease Feb, 2011 | Pubmed ID: 20875859
Altered adult hippocampal neuronal maturation in a rat model of fetal alcohol syndrome.
Brain research Apr, 2011 | Pubmed ID: 21303667
The role of oxidative stress in fetal alcohol spectrum disorders.
Brain research reviews Jun, 2011 | Pubmed ID: 21315761
Voluntary exercise induces adult hippocampal neurogenesis and BDNF expression in a rodent model of fetal alcohol spectrum disorders.
The European journal of neuroscience May, 2011 | Pubmed ID: 21535455
Glutathione restores the mechanism of synaptic plasticity in aged mice to that of the adult.
PloS one , 2011 | Pubmed ID: 21655192
Neurogenesis in Huntington's disease: can studying adult neurogenesis lead to the development of new therapeutic strategies?
Brain research Aug, 2011 | Pubmed ID: 21742312
Anxiety- and depression-like behaviors are accompanied by an increase in oxidative stress in a rat model of fetal alcohol spectrum disorders: Protective effects of voluntary physical exercise.
Neuropharmacology Mar, 2012 | Pubmed ID: 22019722
Omega-3 supplementation can restore glutathione levels and prevent oxidative damage caused by prenatal ethanol exposure.
The Journal of nutritional biochemistry May, 2013 | Pubmed ID: 22841392
Enhanced deficits in long-term potentiation in the adult dentate gyrus with 2nd trimester ethanol consumption.
PloS one , 2012 | Pubmed ID: 23227262
Differential response of hippocampal subregions to stress and learning.
PloS one , 2012 | Pubmed ID: 23285257
Omega-3 fatty acids can reverse the long-term deficits in hippocampal synaptic plasticity caused by prenatal ethanol exposure.
Neuroscience letters Sep, 2013 | Pubmed ID: 23872044
Prenatal ethanol (EtOH) exposure alters the sensitivity of the adult dentate gyrus to acute EtOH exposure.
Alcoholism, clinical and experimental research Jan, 2014 | Pubmed ID: 23915337
Impairments in hippocampal synaptic plasticity following prenatal ethanol exposure are dependent on glutathione levels.
Hippocampus Dec, 2013 | Pubmed ID: 23996467
Hippocampal neurogenesis levels predict WATERMAZE search strategies in the aging brain.
PloS one , 2013 | Pubmed ID: 24086453
Long-term exercise is needed to enhance synaptic plasticity in the hippocampus.
Learning & memory (Cold Spring Harbor, N.Y.) Oct, 2013 | Pubmed ID: 24131795
The role of oxidative stress in Huntington's disease: are antioxidants good therapeutic candidates?
Current drug targets Apr, 2014 | Pubmed ID: 24428525
GluN2A-/- Mice Lack Bidirectional Synaptic Plasticity in the Dentate Gyrus and Perform Poorly on Spatial Pattern Separation Tasks.
Cerebral cortex (New York, N.Y. : 1991) Aug, 2015 | Pubmed ID: 24554729
Physical exercise-induced adult neurogenesis: a good strategy to prevent cognitive decline in neurodegenerative diseases?
BioMed research international , 2014 | Pubmed ID: 24818140
Prenatal ethanol exposure differentially affects hippocampal neurogenesis in the adolescent and aged brain.
Neuroscience Jul, 2014 | Pubmed ID: 24846617
YAC128 Huntington's disease transgenic mice show enhanced short-term hippocampal synaptic plasticity early in the course of the disease.
Brain research Sep, 2014 | Pubmed ID: 24949563
Effects of Ethanol Exposure during Distinct Periods of Brain Development on Hippocampal Synaptic Plasticity.
Brain sciences Jul, 2013 | Pubmed ID: 24961522
Deletion of the NMDA receptor GluN2A subunit significantly decreases dendritic growth in maturing dentate granule neurons.
PloS one , 2014 | Pubmed ID: 25083703
A comparison of the different animal models of fetal alcohol spectrum disorders and their use in studying complex behaviors.
Frontiers in pediatrics , 2014 | Pubmed ID: 25232537
Physical exercise-induced hippocampal neurogenesis and antidepressant effects are mediated by the adipocyte hormone adiponectin.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2014 | Pubmed ID: 25331877
Enhanced corticosteroid signaling alters synaptic plasticity in the dentate gyrus in mice lacking the fragile X mental retardation protein.
Neurobiology of disease May, 2015 | Pubmed ID: 25731748
Time-Course Analysis of Protein and Lipid Oxidation in the Brains of Yac128 Huntington's Disease Transgenic Mice.
Rejuvenation research Apr, 2016 | Pubmed ID: 26371883
Prenatal ethanol exposure impairs temporal ordering behaviours in young adult rats.
Behavioural brain research Feb, 2016 | Pubmed ID: 26632335
The antidepressant-like effect of chronic guanosine treatment is associated with increased hippocampal neuronal differentiation.
The European journal of neuroscience Apr, 2016 | Pubmed ID: 26779605
Effects of pre-natal alcohol exposure on hippocampal synaptic plasticity: Sex, age and methodological considerations.
Neuroscience and biobehavioral reviews May, 2016 | Pubmed ID: 26906760
The effects of hormones and physical exercise on hippocampal structural plasticity.
Frontiers in neuroendocrinology Apr, 2016 | Pubmed ID: 26989000
Chronic minocycline treatment improves social recognition memory in adult male Fmr1 knockout mice.
Behavioural brain research Oct, 2016 | Pubmed ID: 27291517
Hippocampal dysfunction and cognitive impairment in Fragile-X Syndrome.
Neuroscience and biobehavioral reviews Sep, 2016 | Pubmed ID: 27345143
ISX-9 can potentiate cell proliferation and neuronal commitment in the rat dentate gyrus.
Neuroscience Sep, 2016 | Pubmed ID: 27373772
Chronic corticosterone administration reduces dendritic complexity in mature, but not young granule cells in the rat dentate gyrus.
Restorative neurology and neuroscience Sep, 2016 | Pubmed ID: 27567758
Impaired bidirectional NMDA receptor dependent synaptic plasticity in the dentate gyrus of adult female Fmr1 heterozygous knockout mice.
Neurobiology of disease Dec, 2016 | Pubmed ID: 27659109
The potential for animal models to provide insight into mild traumatic brain injury: Translational challenges and strategies.
Neuroscience and biobehavioral reviews May, 2017 | Pubmed ID: 27659125
Mild Traumatic Brain Injury Produces Long-Lasting Deficits in Synaptic Plasticity in the Female Juvenile Hippocampus.
Journal of neurotrauma Mar, 2017 | Pubmed ID: 27735217
The Effects of Ethanol Exposure During Distinct Periods of Brain Development on Oxidative Stress in the Adult Rat Brain.
Alcoholism, clinical and experimental research Jan, 2017 | Pubmed ID: 27862017
Revisiting the flip side: Long-term depression of synaptic efficacy in the hippocampus.
Neuroscience and biobehavioral reviews Sep, 2017 | Pubmed ID: 28624435
Effects of Isx-9 and stress on adult hippocampal neurogenesis: Experimental considerations and future perspectives.
Neurogenesis (Austin, Tex.) , 2017 | Pubmed ID: 28656155
Adolescent ethanol intake alters cannabinoid type-1 receptor localization in astrocytes of the adult mouse hippocampus.
Addiction biology Mar, 2019 | Pubmed ID: 29168269
Chronic minocycline treatment improves hippocampal neuronal structure, NMDA receptor function, and memory processing in Fmr1 knockout mice.
Neurobiology of disease May, 2018 | Pubmed ID: 29367010
Repeated mild traumatic brain injury can cause acute neurologic impairment without overt structural damage in juvenile rats.
PloS one , 2018 | Pubmed ID: 29738554
The Benefits of Exercise on Structural and Functional Plasticity in the Rodent Hippocampus of Different Disease Models.
Brain plasticity (Amsterdam, Netherlands) Oct, 2015 | Pubmed ID: 29765836
Impaired spatial processing in a mouse model of fragile X syndrome.
Behavioural brain research Sep, 2018 | Pubmed ID: 29778627
Diffusion MRI abnormalities in adolescent rats given repeated mild traumatic brain injury.
Annals of clinical and translational neurology Dec, 2018 | Pubmed ID: 30564624
Effects of Voluntary Exercise on Cell Proliferation and Neurogenesis in the Dentate Gyrus of Adult FMR1 Knockout Mice.
Brain plasticity (Amsterdam, Netherlands) Dec, 2018 | Pubmed ID: 30598869
Fetal alcohol spectrum disorder (FASD) affects the hippocampal levels of histone variant H2A.Z-2.
Biochemistry and cell biology = Biochimie et biologie cellulaire Aug, 2019 | Pubmed ID: 30605356
Fragile-X Syndrome Is Associated With NMDA Receptor Hypofunction and Reduced Dendritic Complexity in Mature Dentate Granule Cells.
Frontiers in molecular neuroscience , 2018 | Pubmed ID: 30705620
Mild Closed-Head Injury in Conscious Rats Causes Transient Neurobehavioral and Glial Disturbances: A Novel Experimental Model of Concussion.
Journal of neurotrauma Jul, 2019 | Pubmed ID: 30843474
Endocannabinoid long-term depression revealed at medial perforant path excitatory synapses in the dentate gyrus.
Neuropharmacology Jul, 2019 | Pubmed ID: 31022405
Impaired Bidirectional Synaptic Plasticity in Juvenile Offspring Following Prenatal Ethanol Exposure.
Alcoholism, clinical and experimental research Oct, 2019 | Pubmed ID: 31386206
A Rapid Neurological Assessment Protocol for Repeated Mild Traumatic Brain Injury in Awake Rats.
Current protocols in neuroscience Sep, 2019 | Pubmed ID: 31532919
Intermittent ethanol exposure during adolescence impairs cannabinoid type 1 receptor-dependent long-term depression and recognition memory in adult mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Jan, 2020 | Pubmed ID: 31569197
Modulation of synaptic plasticity by exercise.
International review of neurobiology , 2019 | Pubmed ID: 31607359
Multiple Object Tracking Scores Predict Post-Concussion Status Years after Mild Traumatic Brain Injury.
Journal of neurotrauma Aug, 2020 | Pubmed ID: 31950862
An Engineered Infected Epidermis Model for In Vitro Study of the Skin's Pro-Inflammatory Response.
Micromachines Feb, 2020 | Pubmed ID: 32102205
Hippocampal cognitive impairment in juvenile rats after repeated mild traumatic brain injury.
Behavioural brain research Jun, 2020 | Pubmed ID: 32184155
A Systematic Review of the Effects of Perinatal Alcohol Exposure and Perinatal Marijuana Exposure on Adult Neurogenesis in the Dentate Gyrus.
Alcoholism, clinical and experimental research Jun, 2020 | Pubmed ID: 32246781
Interplay between hormones and exercise on hippocampal plasticity across the lifespan.
Biochimica et biophysica acta. Molecular basis of disease Aug, 2020 | Pubmed ID: 32376385
Endocannabinoid receptors contribute significantly to multiple forms of long-term depression in the rat dentate gyrus.
Learning & memory (Cold Spring Harbor, N.Y.) Sep, 2020 | Pubmed ID: 32817304
Heading in the Right Direction: A Critical Review of Studies Examining the Effects of Heading in Soccer Players.
Journal of neurotrauma Jan, 2021 | Pubmed ID: 32883162
Does Mild Traumatic Brain Injury Increase the Risk for Dementia? A Systematic Review and Meta-Analysis.
Journal of Alzheimer's disease : JAD , 2020 | Pubmed ID: 33044182
Unlocking the brain: A new method for Western blot protein detection from fixed brain tissue.
Journal of neuroscience methods Jan, 2021 | Pubmed ID: 33202258
Acute Δ9-tetrahydrocannabinol prompts rapid changes in cannabinoid CB receptor immunolabeling and subcellular structure in CA1 hippocampus of young adult male mice.
The Journal of comparative neurology Jun, 2021 | Pubmed ID: 33368252
Understanding Changes in Hippocampal Interneurons Subtypes in the Pathogenesis of Alzheimer's Disease: A Systematic Review.
Brain connectivity Apr, 2021 | Pubmed ID: 33559520
AdipoRon Treatment Induces a Dose-Dependent Response in Adult Hippocampal Neurogenesis.
International journal of molecular sciences Feb, 2021 | Pubmed ID: 33669795
Effects of Ethanol on Synaptic Plasticity and NMDA Currents in the Juvenile Rat Dentate Gyrus.
Brain plasticity (Amsterdam, Netherlands) Dec, 2020 | Pubmed ID: 33680851
Chronic AdipoRon Treatment Mimics the Effects of Physical Exercise on Restoring Hippocampal Neuroplasticity in Diabetic Mice.
Molecular neurobiology Sep, 2021 | Pubmed ID: 34164760
Exercise hormone irisin is a critical regulator of cognitive function.
Nature metabolism Aug, 2021 | Pubmed ID: 34417591
Effects of prenatal ethanol exposure on choline-induced long-term depression in the hippocampus.
Journal of neurophysiology Nov, 2021 | Pubmed ID: 34495785
Prenatal alcohol and cannabis exposure can have opposing and region-specific effects on parvalbumin interneuron numbers in the hippocampus.
Alcoholism, clinical and experimental research Nov, 2021 | Pubmed ID: 34523142
Author Correction: Exercise hormone irisin is a critical regulator of cognitive function.
Nature metabolism Oct, 2021 | Pubmed ID: 34621079
Postnatal Choline Supplementation Rescues Deficits in Synaptic Plasticity Following Prenatal Ethanol Exposure.
Nutrients May, 2022 | Pubmed ID: 35631142
ACERCA DE JoVE
Copyright © 2024 MyJoVE Corporation. Todos los derechos reservados