Czech Centre for Phenogenomics,
Laboratory of Transgenic Models of Diseases
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Liver protective effect of ursodeoxycholic acid includes regulation of ADAM17 activity.
BMC gastroenterology Oct, 2013 | Pubmed ID: 24172289
Efficient gene targeting of the Rosa26 locus in mouse zygotes using TALE nucleases.
FEBS letters Nov, 2014 | Pubmed ID: 25241166
Transgenic reporter mice with promoter region of murine LRAT specifically marks lens and meiosis spermatocytes.
Physiological research , 2015 | Pubmed ID: 25317684
KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype.
PLoS genetics Jan, 2017 | Pubmed ID: 28095415
Knockout of Tmem70 alters biogenesis of ATP synthase and leads to embryonal lethality in mice.
Human molecular genetics Nov, 2016 | Pubmed ID: 28173120
Intrinsically disordered proteins drive enamel formation via an evolutionarily conserved self-assembly motif.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2017 | Pubmed ID: 28196895
Plectin controls biliary tree architecture and stability in cholestasis.
Journal of hepatology 05, 2018 | Pubmed ID: 29273475
The role of immune cell subpopulations in the growth and rejection of TC-1/A9 tumors in novel mouse strains differing in the H2-D haplotype and NKC domain.
Oncology letters Mar, 2018 | Pubmed ID: 29467880
Role of in maternal mRNA turnover.
Life science alliance Aug, 2018 | Pubmed ID: 30456367
Aire-expressing ILC3-like cells in the lymph node display potent APC features.
The Journal of experimental medicine May, 2019 | Pubmed ID: 30918005
c-Myb regulates tumorigenic potential of embryonal rhabdomyosarcoma cells.
Scientific reports Apr, 2019 | Pubmed ID: 31004084
Fam208a orchestrates interaction protein network essential for early embryonic development and cell division.
Experimental cell research Sep, 2019 | Pubmed ID: 31112734
Histone methyltransferase PRDM9 is not essential for meiosis in male mice.
Genome research Jul, 2019 | Pubmed ID: 31186301
Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation.
Genome biology 08, 2019 | Pubmed ID: 31446895
Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon.
Cell death & disease Oct, 2019 | Pubmed ID: 31659152
Toll-like receptor 2 expression on c-kit cells tracks the emergence of embryonic definitive hematopoietic progenitors.
Nature communications Nov, 2019 | Pubmed ID: 31729371
The Effect of Lipotoxicity on Renal Dysfunction in a Nonobese Rat Model of Metabolic Syndrome: A Urinary Proteomic Approach.
Journal of diabetes research , 2019 | Pubmed ID: 31886287
CRMP2 mediates Sema3F-dependent axon pruning and dendritic spine remodeling.
EMBO reports Mar, 2020 | Pubmed ID: 31919978
High-throughput discovery of genetic determinants of circadian misalignment.
PLoS genetics Jan, 2020 | Pubmed ID: 31929527
Human and mouse essentiality screens as a resource for disease gene discovery.
Nature communications Jan, 2020 | Pubmed ID: 32005800
The Deep Genome Project.
Genome biology Feb, 2020 | Pubmed ID: 32008577
Dysregulated NADPH Oxidase Promotes Bone Damage in Murine Model of Autoinflammatory Osteomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 03, 2020 | Pubmed ID: 32024700
Toll-like receptor signaling in thymic epithelium controls monocyte-derived dendritic cell recruitment and Treg generation.
Nature communications May, 2020 | Pubmed ID: 32398640
Efficient allele conversion in mouse zygotes and primary cells based on electroporation of Cre protein.
Methods (San Diego, Calif.) Jul, 2021 | Pubmed ID: 32717290
Cytotoxicity of the effector protein BteA was attenuated in Bordetella pertussis by insertion of an alanine residue.
PLoS pathogens Aug, 2020 | Pubmed ID: 32776984
The iRhom2/ADAM17 Axis Attenuates Bacterial Uptake by Phagocytes in a Cell Autonomous Manner.
International journal of molecular sciences Aug, 2020 | Pubmed ID: 32825187
Intronic Determinants Coordinate Charme lncRNA Nuclear Activity through the Interaction with MATR3 and PTBP1.
Cell reports Dec, 2020 | Pubmed ID: 33357424
Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density.
PLoS genetics Dec, 2020 | Pubmed ID: 33370286
Bardet-Biedl Syndrome ciliopathy is linked to altered hematopoiesis and dysregulated self-tolerance.
EMBO reports Feb, 2021 | Pubmed ID: 33426789
SGIP1 is involved in regulation of emotionality, mood, and nociception and modulates in vivo signalling of cannabinoid CB receptors.
British journal of pharmacology Apr, 2021 | Pubmed ID: 33491188
Plectin ensures intestinal epithelial integrity and protects colon against colitis.
Mucosal immunology 05, 2021 | Pubmed ID: 33674761
Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice.
Nature May, 2021 | Pubmed ID: 33767445
Response to correspondence on "Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation".
Genome biology 04, 2021 | Pubmed ID: 33827648
A resource of targeted mutant mouse lines for 5,061 genes.
Nature genetics Apr, 2021 | Pubmed ID: 33833456
Cytoplasmic polyadenylation by TENT5A is required for proper bone formation.
Cell reports Apr, 2021 | Pubmed ID: 33882302
Semi-Lethal Primary Ciliary Dyskinesia in Rats Lacking the Gene.
International journal of molecular sciences Apr, 2021 | Pubmed ID: 33916973
Expression of human-specific ARHGAP11B in mice leads to neocortex expansion and increased memory flexibility.
The EMBO journal Jul, 2021 | Pubmed ID: 33938018
The iRhom homology domain is indispensable for ADAM17-mediated TNFα and EGF receptor ligand release.
Cellular and molecular life sciences : CMLS Jun, 2021 | Pubmed ID: 33950315
Regulation of Inflammatory Response by Transmembrane Adaptor Protein LST1.
Frontiers in immunology , 2021 | Pubmed ID: 33986741
CRL4-DCAF12 Ubiquitin Ligase Controls MOV10 RNA Helicase during Spermatogenesis and T Cell Activation.
International journal of molecular sciences May, 2021 | Pubmed ID: 34065512
ADAM10 and ADAM17 regulate EGFR, c-Met and TNF RI signalling in liver regeneration and fibrosis.
Scientific reports 06, 2021 | Pubmed ID: 34075077
Deletion of TLR2 erythro-myeloid progenitors leads to embryonic lethality in mice.
European journal of immunology Sep, 2021 | Pubmed ID: 34107067
Loss of Wiz Function Affects Methylation Pattern in Palate Development and Leads to Cleft Palate.
Frontiers in cell and developmental biology , 2021 | Pubmed ID: 34150743
LAMP3 deficiency affects surfactant homeostasis in mice.
PLoS genetics Jun, 2021 | Pubmed ID: 34161347
Dual role of Fam208a during zygotic cleavage and early embryonic development.
Experimental cell research Sep, 2021 | Pubmed ID: 34216590
Retraction notice to "Fam208a orchestrates interaction protein network essential for early embryonic development and cell division" [Exp. Cell Res. 382 (1) (2019) 111437].
Experimental cell research Aug, 2021 | Pubmed ID: 34272044
INFRAFRONTIER quality principles in systemic phenotyping.
Mammalian genome : official journal of the International Mammalian Genome Society Mar, 2022 | Pubmed ID: 34328547
Publisher Correction: Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice.
Nature Sep, 2021 | Pubmed ID: 34345019
Heterozygous Mutation Affects Glucose Tolerance in Male Rats.
Genes Jul, 2021 | Pubmed ID: 34356103
The receptor-type protein tyrosine phosphatase CD45 promotes onset and severity of IL-1β-mediated autoinflammatory osteomyelitis.
The Journal of biological chemistry Oct, 2021 | Pubmed ID: 34461100
Correction: Plectin ensures intestinal epithelial integrity and protects colon against colitis.
Mucosal immunology Feb, 2022 | Pubmed ID: 34686840
Novel ADNP Syndrome Mice Reveal Dramatic Sex-Specific Peripheral Gene Expression With Brain Synaptic and Tau Pathologies.
Biological psychiatry Jul, 2022 | Pubmed ID: 34865853
Multi-Level Approach for Comprehensive Enamel Phenotyping.
Current protocols Jan, 2022 | Pubmed ID: 35007410
Correction to: Plectin ensures intestinal epithelial integrity and protects colon against colitis.
Mucosal immunology Mar, 2022 | Pubmed ID: 35301446
Semantic clustering analysis of E3-ubiquitin ligases in gastrointestinal tract defines genes ontology clusters with tissue expression patterns.
BMC gastroenterology Apr, 2022 | Pubmed ID: 35413796
Genome-wide association study identifies kallikrein 5 in type 2 inflammation-low asthma.
The Journal of allergy and clinical immunology Apr, 2022 | Pubmed ID: 35487308
Comprehensive Transcriptional Profiling and Mouse Phenotyping Reveals Dispensable Role for Adipose Tissue Selective Long Noncoding RNA .
Non-coding RNA May, 2022 | Pubmed ID: 35645339
Batch alignment via retention orders for preprocessing large-scale multi-batch LC-MS experiments.
Bioinformatics (Oxford, England) Aug, 2022 | Pubmed ID: 35748696
FBXO38 Ubiquitin Ligase Controls Sertoli Cell Maturation.
Frontiers in cell and developmental biology , 2022 | Pubmed ID: 35769260
Full Assessment of Lung Mechanics Using Computer-Controlled, Forced Oscillation Technique.
Current protocols Jul, 2022 | Pubmed ID: 35834677
Generation and Characterization of a Novel Angelman Syndrome Mouse Model with a Full Deletion of the Gene.
Cells Sep, 2022 | Pubmed ID: 36139390
Self-reactivity of CD8 T-cell clones determines their differentiation status rather than their responsiveness in infections.
Frontiers in immunology , 2022 | Pubmed ID: 36275704
LACTB induces cancer cell death through the activation of the intrinsic caspase-independent pathway in breast cancer.
Apoptosis : an international journal on programmed cell death Feb, 2023 | Pubmed ID: 36282364
Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Molecular cell Nov, 2022 | Pubmed ID: 36332606
Analysis of genome-wide knockout mouse database identifies candidate ciliopathy genes.
Scientific reports Dec, 2022 | Pubmed ID: 36456625
Human neutralizing antibodies to cold linear epitopes and to subdomain 1 of SARS-CoV-2.
bioRxiv : the preprint server for biology Nov, 2022 | Pubmed ID: 36482967
Molecular interactions of adaptor protein PSTPIP2 control neutrophil-mediated responses leading to autoinflammation.
Frontiers in immunology , 2022 | Pubmed ID: 36605205
Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein.
Science immunology Mar, 2023 | Pubmed ID: 36701425
Genome-wide screening reveals the genetic basis of mammalian embryonic eye development.
BMC biology Feb, 2023 | Pubmed ID: 36737727
A structural model of the iRhom-ADAM17 sheddase complex reveals functional insights into its trafficking and activity.
Cellular and molecular life sciences : CMLS Apr, 2023 | Pubmed ID: 37119365
Variation in mouse chemical signals is genetically controlled and environmentally modulated.
Scientific reports May, 2023 | Pubmed ID: 37237091
Spatial Analysis of Nucleotide Metabolism: From CRISPR Knockout Cancer Cells to MALDI Imaging of Tumors.
Methods in molecular biology (Clifton, N.J.) , 2023 | Pubmed ID: 37258772
Comprehensive ECG reference intervals in C57BL/6N substrains provide a generalizable guide for cardiac electrophysiology studies in mice.
Mammalian genome : official journal of the International Mammalian Genome Society Jun, 2023 | Pubmed ID: 37294348
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