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Department of Medical Biosciences
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T-cell Landscape in a Primary Melanoma Predicts the Survival of Patients with Metastatic Disease after Their Treatment with Dendritic Cell Vaccines.
Cancer research Jun, 2016 | Pubmed ID: 27197179
Adjuvant dendritic cell vaccination induces tumor-specific immune responses in the majority of stage III melanoma patients.
Oncoimmunology Jul, 2016 | Pubmed ID: 27622047
The Reticular Cell Network: A Robust Backbone for Immune Responses.
PLoS biology Oct, 2016 | Pubmed ID: 27727272
Harnessing RNA sequencing for global, unbiased evaluation of two new adjuvants for dendritic-cell immunotherapy.
Oncotarget Mar, 2017 | Pubmed ID: 28186996
Eight-Color Multiplex Immunohistochemistry for Simultaneous Detection of Multiple Immune Checkpoint Molecules within the Tumor Microenvironment.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2018 | Pubmed ID: 29141863
Spontaneous Regression of Ovarian Carcinoma After Septic Peritonitis; A Unique Case Report.
Frontiers in oncology , 2018 | Pubmed ID: 30555799
Human pDCs Are Superior to cDC2s in Attracting Cytolytic Lymphocytes in Melanoma Patients Receiving DC Vaccination.
Cell reports Jan, 2020 | Pubmed ID: 31995747
Is T Cell Negative Selection a Learning Algorithm?
Cells Mar, 2020 | Pubmed ID: 32168897
Testing Graphical Causal Models Using the R Package "dagitty".
Current protocols Feb, 2021 | Pubmed ID: 33592130
Human type 1 and type 2 conventional dendritic cells express indoleamine 2,3-dioxygenase 1 with functional effects on T cell priming.
European journal of immunology Jun, 2021 | Pubmed ID: 33675038
Local actin dynamics couple speed and persistence in a cellular Potts model of cell migration.
Biophysical journal Jul, 2021 | Pubmed ID: 34022237
A tipping point in cancer-immune dynamics leads to divergent immunotherapy responses and hampers biomarker discovery.
Journal for immunotherapy of cancer May, 2021 | Pubmed ID: 34059522
Immunophenotyping Reveals Longitudinal Changes in Circulating Immune Cells During Radium-223 Therapy in Patients With Metastatic Castration-Resistant Prostate Cancer.
Frontiers in oncology , 2021 | Pubmed ID: 34084750
Cytotoxic T cells are able to efficiently eliminate cancer cells by additive cytotoxicity.
Nature communications Sep, 2021 | Pubmed ID: 34471116
Paired primary and metastatic lesions of patients with ipilimumab-treated melanoma: high variation in lymphocyte infiltration and HLA-ABC expression whereas tumor mutational load is similar and correlates with clinical outcome.
Journal for immunotherapy of cancer May, 2022 | Pubmed ID: 35550553
Tumor microenvironment shows an immunological abscopal effect in patients with NSCLC treated with pembrolizumab-radiotherapy combination.
Journal for immunotherapy of cancer Oct, 2022 | Pubmed ID: 36252995
Interpreting T-cell search "strategies" in the light of evolution under constraints.
PLoS computational biology Feb, 2023 | Pubmed ID: 36848395
In silico cancer immunotherapy trials uncover the consequences of therapy-specific response patterns for clinical trial design and outcome.
Nature communications Apr, 2023 | Pubmed ID: 37095077
Radboudumc
Radboud University
Mark A. J. Gorris1,2,
Evgenia Martynova*,1,3,
Mark W. D. Sweep*,1,4,
Iris A. E. van der Hoorn1,5,
Shabaz Sultan1,3,
Mike J. D. E. Claassens1,
Lieke L. van der Woude1,2,6,
Kiek Verrijp1,2,6,
Carl G. Figdor1,3,
Johannes Textor1,3,
I. Jolanda M. de Vries1
1Department of Medical BioSciences, Radboudumc,
2Division of Immunotherapy, Oncode Institute, Radboudumc,
3Data Science, Institute for Computing and Information Sciences, Radboud University,
4Department of Medical Oncology, Radboudumc,
5Department of Pulmonary Diseases, Radboudumc,
6Department of Pathology, Radboudumc
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