Ziduan Ding

Synaptic scaling of corticostriatal circuits underlies hyperactivity in GABA Transporter-1 deficient mice.

Exploring the components and mechanism of L. for colon cancer treatment based on network pharmacology and molecular docking.

Proteogenomics of diffuse gliomas reveal molecular subtypes associated with specific therapeutic targets and immune-evasion mechanisms.

Ruxolitinib Alleviates Inflammation, Apoptosis, and Intestinal Barrier Leakage in Ulcerative Colitis via STAT3.

HIF2α-induced upregulation of RNASET2 promotes triglyceride synthesis and enhances cell migration in clear cell renal cell carcinoma.

Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1.

Loss of C3a and C5a receptors promotes adipocyte browning and attenuates diet-induced obesity via activating inosine/A2aR pathway.

Immune microenvironment: novel perspectives on bone regeneration disorder in osteoradionecrosis of the jaws.

PRPS2 mutations drive acute lymphoblastic leukemia relapse through influencing PRPS1/2 hexamer stability.

Recent advances in long-acting drug delivery systems for anticancer drug.

Choroidal structural changes following vitrectomy performed with phacoemulsification in unilateral idiopathic epiretinal membrane.

A small-molecule drug inhibits autophagy gene expression through the central regulator TFEB.

Artificial Base-Directed Assembly of an Albumin-siRNA Complex for Tumor-Targeting Delivery.

Aberrant functional connectivity of the bed nucleus of the stria terminalis and its age dependence in children and adolescents with social anxiety disorder.

Genome-wide association study using whole-genome sequencing identifies risk loci for Parkinson's disease in Chinese population.

Development of a Machine-Learning Model for Prediction of Extubation Failure in Patients with Difficult Airways after General Anesthesia of Head, Neck, and Maxillofacial Surgeries.

Resistance to immune checkpoint inhibitors in advanced lung cancer: Clinical characteristics, potential prognostic factors and next strategy.

Netrin-1 Monoclonal Antibody-Functionalized Nanoparticle Loaded with Metformin Prevents the Progression of Abdominal Aortic Aneurysms.

Classification, risk factors, and outcomes of patients with progressive hemorrhagic injury after traumatic brain injury.

Expert consensus on the diagnosis and treatment of severe and critical coronavirus disease 2019 (COVID-19).

Channel- and category-specific emotion recognition deficits and their associations with symptomatology and cognition in individuals with schizophrenia.

The prognostic value of splenic abnormalities in pretreatment F-FDG PET/CT in patients with complete response diffuse large B-cell lymphoma.

Reconstruction of the tumor spatial microenvironment along the malignant-boundary-nonmalignant axis.

Adaptive immune dysfunction in patients with COVID-19 and impaired kidney function during the omicron surge.

Clinical characteristics and outcomes of follicular lymphoma patients with extranodal involvement: analysis of a series of 1090 cases in China.

Self-Homeostasis Immunoregulatory Strategy for Implant-Related Infections through Remodeling Redox Balance.

Nanomedicine-Enabled Sonomechanical, Sonopiezoelectric, Sonodynamic, and Sonothermal Therapy.

Intra-articular treatment of temporomandibular joint osteoarthritis by injecting actively-loaded meloxicam liposomes with dual-functions of anti-inflammation and lubrication.

PKCδ promotes the invasion and migration of colorectal cancer through c-myc/NDRG1 pathway.

Identification of NLE1/CDK1 axis as key regulator in the development and progression of non-small cell lung cancer.

Glycolysis drives STING signaling to facilitate dendritic cell antitumor function.

Local glucose elevation activates pyroptosis via NLRP3 inflammasome in ovarian granulosa cells of overweight patients.

The Combined Effect of Polygenic Risk Score and Prostate Health Index in Chinese Men Undergoing Prostate Biopsy.

Association of Serum BAFF Levels with Cardiovascular Events in ST-Segment Elevation Myocardial Infarction.

Involvement of Transcriptional Factor Pbx1 in Peripheral B Cell Homeostasis to Constrain Lupus Autoimmunity.

CD206 tumor-associated macrophages interact with CD4 tumor-infiltrating lymphocytes and predict adverse patient outcome in human laryngeal squamous cell carcinoma.

Obesity-induced oxidative stress and mitochondrial dysfunction negatively affect sperm quality.

Association of perfluoroalkyl substances with pulmonary function in adolescents (NHANES 2007-2012).

Simultaneous online SPE-HPLC-MS/MS quantification of gefitinib, osimertinib and icotinib in dried plasma spots: Application to therapeutic drug monitoring in patients with non-small cell lung cancer.

YY1-induced upregulation of LncRNA-ARAP1-AS2 and ARAP1 promotes diabetic kidney fibrosis aberrant glycolysis associated with EGFR/PKM2/HIF-1α pathway.

Effects of osteogenic growth peptide C-terminal pentapeptide and its analogue on bone remodeling in an osteoporosis rat model.

Cartilage Lacuna-Inspired Microcarriers Drive Hyaline Neocartilage Regeneration.

Mechanisms underlying capsulotomy for refractory obsessive-compulsive disorder: neural correlates of negative affect processing overlap with deep brain stimulation targets.

Rational polyelectrolyte nanoparticles endow preosteoclast-targeted siRNA transfection for anabolic therapy of osteoporosis.

Roles and mechanisms of tumour-infiltrating B cells in human cancer: a new force in immunotherapy.

Risk of subclinical atherosclerosis across metabolic transition in individuals with or without fatty liver disease: a prospective cohort study.

Histone demethylase KDM5B licenses macrophage-mediated inflammatory responses by repressing Nfkbia transcription.

Impaired emotion perception in schizophrenia shows sex differences with channel- and category-specific effects: A pilot study.

Glucagon-like peptide-1 receptor agonists decrease hyperinsulinemia and hyperandrogenemia in dehydroepiandrosterone-induced polycystic ovary syndrome mice and are associated with mitigating inflammation and inducing browning of white adipose tissue†.

Correlations between intravoxel incoherent motion-derived fast diffusion and perfusion fraction parameters and VEGF- and MIB-1-positive rates in brain gliomas: an intraoperative MR-navigated, biopsy-based histopathologic study.

N - Methyladenosine defines a new checkpoint in γδ T cell development.

STING activation in platelets aggravates septic thrombosis by enhancing platelet activation and granule secretion.

CT-derived fractional flow reserve for prediction of major adverse cardiovascular events in diabetic patients.

Structural and functional characterization of novel F7 mutations identified in Chinese factor VII-deficient patients.

A Fluid Multivalent Magnetic Interface for High-Performance Isolation and Proteomic Profiling of Tumor-Derived Extracellular Vesicles.

Integrative proteogenomic characterization of early esophageal cancer.

Complex clinical manifestations and new insights in RNA sequencing of children with diabetes and variants.

Age- and sex-dependent increase in self-harm among adolescents with mental health problems in East China during COVID-19 related society-wide isolation.

Mechanism-Driven Technology Development for Solving the Intracellular Delivery Problem of Hard-To-Transfect Cells.

Alleviate Periodontitis and Its Comorbidity Hypertension using a Nanoparticle-Embedded Functional Hydrogel System.

New insights into immune cell diversity in acute kidney injury.

Improving lesion conspicuity in abdominal dual-energy CT with deep learning image reconstruction: a prospective study with five readers.

Correlation Analysis of Promoter Polymorphism and Function in Patients with Dilated Cardiomyopathy.

Surgical Options for Appropriate Length of J-Pouch Construction for Better Outcomes and Long-term Quality of Life in Patients with Ulcerative Colitis after Ileal Pouch-Anal Anastomosis.

Latest incidence and electrocardiographic predictors of atrial fibrillation: a prospective study from China.

Sugemalimab Monotherapy for Patients With Relapsed or Refractory Extranodal Natural Killer/T-Cell Lymphoma (GEMSTONE-201): Results From a Single-Arm, Multicenter, Phase II Study.

The 20 years transition of clinical characteristics and metabolic risk factors in primary liver cancer patients from China.

Integrative analysis revealed that distinct cuprotosis patterns reshaped tumor microenvironment and responses to immunotherapy of colorectal cancer.

A comparative study on various cell sources for constructing tissue-engineered meniscus.

Role of IL-17A in different stages of ischemic stroke.

Reading and writing of mRNA mA modification orchestrate maternal-to-zygotic transition in mice.

PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1.

Sovleplenib (HMPL-523), a novel Syk inhibitor, for patients with primary immune thrombocytopenia in China: a randomised, double-blind, placebo-controlled, phase 1b/2 study.

Preclinical safety evaluation of calcineurin inhibitors delivered through an intraductal route to prevent post-ERCP pancreatitis demonstrates endocrine and systemic safety.

Melatonin ameliorates glyphosate- and hard water-induced renal tubular epithelial cell senescence via PINK1-Parkin-dependent mitophagy.

Investigating the causal association between branched-chain amino acids and Alzheimer's disease: A bidirectional Mendelian randomized study.

Corrigendum: The correlation between collagen types and ultrasound feature score in evaluating the vulnerability of carotid artery plaque.

Assisted reproductive technology and neurodevelopmental outcomes in offspring: a prospective birth cohort study in East China.

Evaluation of Image Quality and Detectability of Deep Learning Image Reconstruction (DLIR) Algorithm in Single- and Dual-energy CT.

Biomarkers of aging.

Meta-analysis of the association between dietary inflammatory index and cognitive health.

Staphylococcal scalded skin syndrome in a child.

Glutamate dehydrogenase1 supports HIF-1α stability to promote colorectal tumorigenesis under hypoxia.

Machine Learning to Dynamically Predict In-Hospital Venous Thromboembolism After Inguinal Hernia Surgery: Results From the CHAT-1 Study.

Regulation of Hsa-miR-4639-5p expression and its potential role in the pathogenesis of Parkinson's disease.

An artificial intelligence framework for the diagnosis of prosthetic joint infection based on Tc-MDP dynamic bone scintigraphy.

ACLY-β-catenin axis modulates hepatoblastoma cell proliferation.

Bioprinted constructs that simulate nerve-bone crosstalk to improve microenvironment for bone repair.

A case-report of the unprovoked thrombotic event in a patient with thymoma and severe FVII deficiency.

High Expression of Tumor HLA-DR Predicts Better Prognosis and Response to Anti-PD-1 Therapy in Laryngeal Squamous Cell Carcinoma.

Single-cell atlas reveals a distinct immune profile fostered by T cell-B cell crosstalk in triple negative breast cancer.

The association of dietary inflammatory potential with sarcopenia in Chinese community-dwelling older adults.

A combined radiomic model distinguishing GISTs from leiomyomas and schwannomas in the stomach based on endoscopic ultrasonography images.

Whole-exome sequencing study of hypospadias.

The safety concerns regarding immune checkpoint inhibitors in liver cancer patients rising mainly from CHB.

Spatio-temporal pattern of c-Jun N-terminal kinase isoforms in the cochleae of C57BL/6J mice with presbycusis.

Integration of ATAC-Seq and RNA-Seq reveals FOSL2 drives human liver progenitor-like cell aging by regulating inflammatory factors.

Community-based rehabilitation interventions on quality of care for people with schizophrenia in China (CRISC): study protocol for a cluster-randomized controlled trial.

Isolation and characterization of a novel Enterococcus phage Phi_Eg_SY1.

Associations between sleep disturbance, inflammatory markers and depressive symptoms: Mediation analyses in a large NHANES community sample.

Nomograms referenced by cardiac magnetic resonance in the prediction of cardiac injuries in patients with ST-elevation myocardial infarction.

Granulosa cell mevalonate pathway abnormalities contribute to oocyte meiotic defects and aneuploidy.

Bisphenol A substitutes and childhood obesity at 7 years: a cross-sectional study in Shandong, China.

Study on the Interaction between Silibinin and Neuraminidase.

Natural γδT17 cell development and functional acquisition is governed by the mTORC2--Maf-controlled mitochondrial fission pathway.

Exploring the role of pyroptosis in shaping the tumor microenvironment of colorectal cancer by bulk and single-cell RNA sequencing.

Polyamine metabolism patterns characterized tumor microenvironment, prognosis, and response to immunotherapy in colorectal cancer.

Four trajectories of 24-hour urine protein levels in real-world lupus nephritis cohorts.

Predicting F-FDG SUVs of metastatic pulmonary nodes from CT images in patients with differentiated thyroid cancer by using a convolutional neural network.

Fibroblast growth factor 21 attenuates ventilator-induced lung injury by inhibiting the NLRP3/caspase-1/GSDMD pyroptotic pathway.

Radiofrequency Ablation of Unifocal Papillary Thyroid Microcarcinoma With BRAF V600E Mutation.

The First-in-Human Whole-Body Dynamic Pharmacokinetics Study of Aptamer.

SOV sensitizes gastric cancer cells to radiation by suppressing radiation-induced autophagy in vitro and in vivo.

The role of KNTC1 in the regulation of proliferation, migration and tumorigenesis in colorectal cancer.

Globus pallidus internus versus subthalamic nucleus deep brain stimulation for isolated dystonia: A 3-year follow-up.

Chinese university students showed less disordered eating during the COVID-19 campus lockdown.

Effectiveness of Community-Based Rehabilitation Interventions on Symptoms and Functioning for People with Schizophrenia: A Systematic Review and Meta-Analysis.

Nirmatrelvir/Ritonavir for hemodialysis patients with COVID-19.

Systematic analysis of the prognostic and immunological role of DHX33 in pan-cancer.

Inflammatory bowel disease is associated with an increased risk of adverse events in patients undergoing joint arthroplasty.

Structural Basis of Low-Molecular-Weight Thiol Glycosylation in Lincomycin A Biosynthesis.

Enoxaparin sodium bone cement displays local anti-inflammatory effects by regulating the expression of IL-6 and TNF-α.

A T-specific long noncoding RNA maintains immune-metabolic homeostasis in aging liver.

Effects of home-based chronic wound care training for patients and caregivers: A systematic review.

TRAmHap: accurate prediction of transcriptional activity from DNA methylation haplotypes in bisulfite-sequencing data.

Editorial: Construction and biological applications of programmable DNA dynamic reactions.

Evaluation of Schlemm's canal with swept-source optical coherence tomography in primary angle-closure disease.

A systematic review of radiomics in giant cell tumor of bone (GCTB): the potential of analysis on individual radiomics feature for identifying genuine promising imaging biomarkers.

Urogenital sinus malformation: From development to management.

Organophosphate esters, airway inflammation, and lung function among U.S. participants: A nationally representative cross-sectional study from NHANES, 2011-2012.

Percutaneous Magnetic Resonance Imaging-Guided Coaxial Cutting Needle Biopsy of Pancreatic Lesions: Diagnostic Accuracy and Safety.

Targeting KAT2A inhibits inflammatory macrophage activation and rheumatoid arthritis through epigenetic and metabolic reprogramming.

A novel pathogenic variant of in an infant with Senior-Loken syndrome.

Reactive cutaneous capillary endothelial proliferation predicted the efficacy of camrelizumab in patients with recurrent/metastatic head and neck squamous cell carcinoma.

Prevalence of psoriatic arthritis in Chinese population with psoriasis: A multicenter study conducted by experienced rheumatologists.

An overview of meta-analyses on radiomics: more evidence is needed to support clinical translation.

Comparison of different treatment approaches for coronoid process fracture in terrible triad injury: a multicenter, randomized controlled study.

Evidence Accumulation and Neural Correlates of Uncertainty in Obsessive-Compulsive Disorder.

Association of parabens and bisphenols with lung function in children aged 5-12 years from Shanghai, China.

Differential regulation of JAK1 expression by ETS1 associated with predisposition to primary biliary cholangitis.

Combination of iris vessel area density and surgery interval as the predictor of perceived pain during consecutive second-eye cataract surgery.

Lactoferrin attenuates cardiac fibrosis and cardiac remodeling after myocardial infarction via inhibiting mTORC1/S6K signaling pathway.

N6-methyladenosine methylation mediates non-coding RNAs modification in microplastic-induced cardiac injury.

Impact of a novel prognostic model on allogeneic hematopoietic stem cell transplantation outcomes in patients with CMML.

Paxlovid for hospitalized COVID-19 patients with chronic kidney disease.

METTL3 boosts mitochondrial fission and induces cardiac fibrosis by enhancing LncRNA GAS5 methylation.

The trends of psychosomatic symptoms and perceived stress among healthcare workers during the COVID-19 pandemic in China: Four cross-sectional nationwide surveys, 2020-2023.

Prolyl endopeptidase remodels macrophage function as a novel transcriptional coregulator and inhibits fibrosis.

Learning curve of trans-areola single-site endoscopic thyroidectomy in a high-volume center: A CUSUM-based assessment.

ITGBL1 mediates fibroblast-cardiomyocyte crosstalk to promote cardiac fibrosis and hypertrophy.

Costunolide alleviated DDC induced ductular reaction and inflammatory response in murine model of cholestatic liver disease.

ATP-citrate lyase controls endothelial gluco-lipogenic metabolism and vascular inflammation in sepsis-associated organ injury.

CKBA suppresses mast cell activation via ERK signaling pathway in murine atopic dermatitis.

Hearing Assistive Technology Facilitates Sentence-in-Noise Recognition in Chinese Children With Autism Spectrum Disorder.

Enhanced tyrosine sulfation is associated with chronic kidney disease-related atherosclerosis.

Expression pattern of PD-1/PD-L1 in primary liver cancer with clinical correlation.

Three-dimensional genome structure and function.

Efficacy and safety of microneedling, fractional CO laser, and cryotherapy combined with 5-aminolevulinic acid photodynamic therapy in the treatment of actinic keratosis: A multicenter prospective randomized controlled study.

Correction: Evaluation of Schlemm's canal with swept-source optical coherence tomography in primary angle-closure disease.

Interventional hydrogel microsphere vaccine as an immune amplifier for activated antitumour immunity after ablation therapy.

Innovative breakthroughs facilitated by single-cell multi-omics: manipulating natural killer cell functionality correlates with a novel subcategory of melanoma cells.

Identification of a psychiatric risk gene NISCH at 3p21.1 GWAS locus mediating dendritic spine morphogenesis and cognitive function.

Identification of promoting better prognosis in papillary thyroid carcinoma along with Hashimoto's thyroiditis through WGCNA analysis.

Comparative study of normal condyle and temporomandibular joint prosthesis movement during mouth opening by dynamic magnetic resonance imaging and computed tomography.

The Current Progress of Tetrahedral DNA Nanostructure for Antibacterial Application and Bone Tissue Regeneration.

3D-printed biodegradable magnesium alloy scaffolds with zoledronic acid-loaded ceramic composite coating promote osteoporotic bone defect repair.

Editorial: New insights into the role of mycobiome in diseases.

Proteogenomics of clear cell renal cell carcinoma response to tyrosine kinase inhibitor.

The Aging Biomarker Consortium represents a new era for aging research in China.

The Oxysterol Receptor EBI2 Links Innate and Adaptive Immunity to Limit IFN Response and Systemic Lupus Erythematosus.

A novel heterozygous variant of FOXJ1 in a Chinese female with primary ciliary dyskinesia and hydrocephalus: A case report and literature review.

Preoperative chemotherapy prior to primary tumour resection for asymptomatic synchronous unresectable colorectal liver-limited metastases: The RECUT multicenter randomised controlled trial.

Branched-chain amino acids promote thrombocytopoiesis by activating mTOR signaling.

Long-term prognostic benefit of adjuvant chemotherapy for patients with hepatoid adenocarcinoma of the stomach after radical resection: A national multicenter study.

Integrated models of blood protein and metabolite enhance the diagnostic accuracy for Non-Small Cell Lung Cancer.

Combined aspartate aminotransferase level and PE-SARD score predict 1-month bleeding risk in acute pulmonary embolism.

CD93 overexpresses in liver hepatocellular carcinoma and represents a potential immunotherapy target.

Clinical Features and Predictive Nomogram of Acute Kidney Injury in Aging Population Infected with SARS-CoV-2 Omicron Variant.

Knowledge about schizophrenia test: the Chinese Mandarin version and its sociodemographic and clinical factors.

A pilot study of camrelizumab with docetaxel and cisplatin for the first line treatment in recurrent/metastatic oral squamous cell carcinoma.

Hyaluronic acid-modified and verteporfin-loaded polylactic acid nanogels promote scarless wound healing by accelerating wound re-epithelialization and controlling scar formation.

Investigation of the relationship between changes in maternal coagulation profile in the first trimester and the risk of developing preeclampsia.

Association of the Severity of Hypertensive Disorders in Pregnancy with Birthweight, Childhood Obesity, and Blood Pressure at Age 7.

Achievement of Guideline-Recommended Targets in Diabetes Care in China : A Nationwide Cross-Sectional Study.

TNFAIP2 confers cisplatin resistance in head and neck squamous cell carcinoma via KEAP1/NRF2 signaling.

Single-cell profiling reveals the trajectory of FOLR2-expressing tumor-associated macrophages to regulatory T cells in the progression of lung adenocarcinoma.

Postoperative dysesthesia after PVCR without anterior support applied in Yang's type A severe spinal kyphoscoliosis.

Targeting Bcl-xL is a potential therapeutic strategy for extranodal NK/T cell lymphoma.

Does the timing of intake matter? Association between caffeine intake and depression: Evidence from the National Health and Nutrition Examination Survey.

A novel radiographic analysis system for subaxial cervical spine pedicle screw placement.

Emerging therapies in cancer metabolism.

Disruption of Histamine-HR signaling exacerbates cardiac microthrombosis after periodontal disease via TLR4/NFκB-p65 pathway.

Enhancing prognostic accuracy in head and neck squamous cell carcinoma chemotherapy via a lipid metabolism-related clustered polygenic model.

An observational study on the effect of seasonal variation on peritoneal dialysis patients.

Time-locked acute alpha-frequency stimulation of subthalamic nuclei during the evaluation of emotional stimuli and its effect on power modulation.

AAV-Mediated nuclear localized PGC1α4 delivery in muscle ameliorates sarcopenia and aging-associated metabolic dysfunctions.

[Injectable hydrogel microspheres experimental research for the treatment of osteoarthritis].

Drug resistance and new therapies in gallbladder cancer.

The "Paired Learning by Doing" Approach for Capacity Building Derived from the China-UK-Tanzania Pilot Project on Malaria Control During 2015-2018.

Near-infrared light-activated ROS generation using semiconducting polymer nanocatalysts for photodynamic-chemodynamic therapy.