Thomas M. Vondriska

Molecular conformation dictates signaling module formation: example of PKCepsilon and Src tyrosine kinase.

Formation of protein kinase C(epsilon)-Lck signaling modules confers cardioprotection.

Protein kinase C epsilon signaling complexes include metabolism- and transcription/translation-related proteins: complimentary separation techniques with LC/MS/MS.

Functional proteomics to study protection of the ischaemic myocardium.

Protein tyrosine kinase signaling is necessary for NO donor-induced late preconditioning against myocardial stunning.

Cardioprotection involves activation of NF-kappa B via PKC-dependent tyrosine and serine phosphorylation of I kappa B-alpha.

Functional proteomic analysis of the protein kinase C signaling system.

Multiprotein signaling complexes and regulation of cardiac phenotype.

Cardiac toxic effects of trans-2-hexenal are mediated by induction of cardiomyocyte apoptotic pathways.

Bmx, a member of the Tec family of nonreceptor tyrosine kinases, is a novel participant in pharmacological cardioprotection.

Scaffold proteins and assembly of multiprotein signaling complexes.

Nitric oxide donors protect murine myocardium against infarction via modulation of mitochondrial permeability transition.

Functional proteomic analysis of a three-tier PKCepsilon-Akt-eNOS signaling module in cardiac protection.

Cardiovascular-related proteins identified in human plasma by the HUPO Plasma Proteome Project pilot phase.

The murine cardiac 26S proteasome: an organelle awaiting exploration.

A functional annotation of subproteomes in human plasma.

Signal transduction network motifs and biological memory.

The minimum information about a proteomics experiment (MIAPE).

Protein targets of oxidized phospholipids in endothelial cells.

Cardiovascular Initiative of the Human Proteome Organisation, 5th Workshop October 2007, Seoul, Korea.

Systematic characterization of the murine mitochondrial proteome using functionally validated cardiac mitochondria.

Acrolein consumption exacerbates myocardial ischemic injury and blocks nitric oxide-induced PKCepsilon signaling and cardioprotection.

Altered proteome biology of cardiac mitochondria under stress conditions.

Deducing topology of protein-protein interaction networks from experimentally measured sub-networks.

Loss of Bmx nonreceptor tyrosine kinase prevents pressure overload-induced cardiac hypertrophy.

A new (heat) shocking player in cardiac hypertrophy.

The effects of cascade length, kinetics and feedback loops on biological signal transduction dynamics in a simplified cascade model.

Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells.

Target identification using drug affinity responsive target stability (DARTS).

Post-translational regulation of calsarcin-1 during pressure overload-induced cardiac hypertrophy.

Stress signaling by Tec tyrosine kinase in the ischemic myocardium.

Specialized compartments of cardiac nuclei exhibit distinct proteomic anatomy.

Highly efficient purification of protein complexes from mammalian cells using a novel streptavidin-binding peptide and hexahistidine tandem tag system: application to Bruton's tyrosine kinase.

Proteomic insights into cardiac cell death and survival.

Genomes, proteomes, and the central dogma.

Quantitative analysis of the chromatin proteome in disease reveals remodeling principles and identifies high mobility group protein B2 as a regulator of hypertrophic growth.

Preclinical trials: Keep 'reproducibility' in context.

Features of endogenous cardiomyocyte chromatin revealed by super-resolution STED microscopy.

Structural considerations for chromatin state models with transcription as a functional readout.