Weston B. Struwe

Physical and Theoretical Chemistry Laboratory, University of Oxford

Research Area

Biochemistry

Biography

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JoVE Journal Publications

Article Total : 1	Year
Publication title	2024

Other Publications

Article	Year
The Minimum Information Required for a Glycomics Experiment (MIRAGE) Project: Improving the Standards for Reporting Mass-spectrometry-based Glycoanalytic Data. Molecular & cellular proteomics : MCP\| PubMed ID: 23378518	2013
Increase in sialylation and branching in the mouse serum N-glycome correlates with inflammation and ovarian tumour progression. PloS one\| PubMed ID: 24023608	2013
MIRAGE: the minimum information required for a glycomics experiment. Glycobiology\| PubMed ID: 24653214	2014
Ejection of structural zinc leads to inhibition of γ-butyrobetaine hydroxylase. Bioorganic & medicinal chemistry letters\| PubMed ID: 25266780	2014
Native mass spectrometry: towards high-throughput structural proteomics. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 25502208	2015
Studying the active-site loop movement of the São Paolo metallo-β-lactamase-1†Electronic supplementary information (ESI) available: Procedures for protein expression and purification, F-labe... Chemical science\| PubMed ID: 25717359	2015
GlycoMob: an ion mobility-mass spectrometry collision cross section database for glycomics. Glycoconjugate journal\| PubMed ID: 26314736	2016
Structural characterization and biological implications of sulfated N-glycans in a serine protease from the neotropical moth Hylesia metabus (Cramer [1775]) (Lepidoptera: Saturniidae). Glycobiology\| PubMed ID: 26537504	2016
Optimal Synthetic Glycosylation of a Therapeutic Antibody. Angewandte Chemie (International ed. in English)\| PubMed ID: 26756880	2016
High-resolution mass spectrometry of small molecules bound to membrane proteins. Nature methods\| PubMed ID: 26901650	2016
Travelling-wave ion mobility and negative ion fragmentation of high-mannose N-glycans. Journal of mass spectrometry : JMS\| PubMed ID: 26956389	2016
Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein. Cell reports\| PubMed ID: 26972002	2016
Immune recruitment or suppression by glycan engineering of endogenous and therapeutic antibodies. Biochimica et biophysica acta\| PubMed ID: 27105835	2016
Structures of mammalian ER α-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 27462106	2016
Travelling-wave ion mobility mass spectrometry and negative ion fragmentation of hybrid and complex N-glycans. Journal of mass spectrometry : JMS\| PubMed ID: 27477117	2016
Optimal Synthetic Glycosylation of a Therapeutic Antibody. Angewandte Chemie (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 27546920	2016
Antibody production using a ciliate generates unusual antibody glycoforms displaying enhanced cell-killing activity. mAbs\| PubMed ID: 27594301	2016
The minimum information required for a glycomics experiment (MIRAGE) project: sample preparation guidelines for reliable reporting of glycomics datasets. Glycobiology\| PubMed ID: 27654115	2016
Ion mobility separation of deprotonated oligosaccharide isomers - evidence for gas-phase charge migration. Chemical communications (Cambridge, England)\| PubMed ID: 27711324	2016
Molecular Architecture of the Cleavage-Dependent Mannose Patch on a Soluble HIV-1 Envelope Glycoprotein Trimer. Journal of virology\| PubMed ID: 27807235	2017
Global N-Glycan Site Occupancy of HIV-1 gp120 by Metabolic Engineering and High-Resolution Intact Mass Spectrometry. ACS chemical biology\| PubMed ID: 27984693	2017
The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting glycan microarray-based data. Glycobiology\| PubMed ID: 27993942	2017
The role of interfacial lipids in stabilizing membrane protein oligomers. Nature\| PubMed ID: 28077870	2017
Identification of Lewis and Blood Group Carbohydrate Epitopes by Ion Mobility-Tandem-Mass Spectrometry Fingerprinting. Analytical chemistry\| PubMed ID: 28192913	2017
The Tetrameric Plant Lectin BanLec Neutralizes HIV through Bidentate Binding to Specific Viral Glycans. Structure (London, England : 1993)\| PubMed ID: 28434916	2017
Glycan Fingerprinting via Cold-Ion Infrared Spectroscopy. Angewandte Chemie (International ed. in English)\| PubMed ID: 28513924	2017
Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP Trimers. Journal of virology\| PubMed ID: 28539451	2017
Convergent immunological solutions to Argentine hemorrhagic fever virus neutralization. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 28630325	2017
Glycosylation profiling to evaluate glycoprotein immunogens against HIV-1. Expert review of proteomics\| PubMed ID: 28870097	2017
Integrity of Glycosylation Processing of a Glycan-Depleted Trimeric HIV-1 Immunogen Targeting Key B-Cell Lineages. Journal of proteome research\| PubMed ID: 29420040	2018
Structural principles that enable oligomeric small heat-shock protein paralogs to evolve distinct functions. Science (New York, N.Y.)\| PubMed ID: 29472485	2018
Isomer Information from Ion Mobility Separation of High-Mannose Glycan Fragments. Journal of the American Society for Mass Spectrometry\| PubMed ID: 29508223	2018
Collision Cross Sections and Ion Mobility Separation of Fragment Ions from Complex N-Glycans. Journal of the American Society for Mass Spectrometry\| PubMed ID: 29675741	2018
Fucose Migration in Intact Protonated Glycan Ions: A Universal Phenomenon in Mass Spectrometry. Angewandte Chemie (International ed. in English)\| PubMed ID: 29688603	2018
Quantitative mass imaging of single biological macromolecules. Science (New York, N.Y.)\| PubMed ID: 29700264	2018
Signature of Antibody Domain Exchange by Native Mass Spectrometry and Collision-Induced Unfolding. Analytical chemistry\| PubMed ID: 29757629	2018
Structural Studies of Fucosylated N-Glycans by Ion Mobility Mass Spectrometry and Collision-Induced Fragmentation of Negative Ions. Journal of the American Society for Mass Spectrometry\| PubMed ID: 29790113	2018
Structural Insights into the Broad-Spectrum Antiviral Target Endoplasmic Reticulum Alpha-Glucosidase II. Advances in experimental medicine and biology\| PubMed ID: 29845539	2018
The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases. Nature chemical biology\| PubMed ID: 29915238	2018
Publisher Correction: The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases. Nature chemical biology\| PubMed ID: 29950663	2018
N-glycan microheterogeneity regulates interactions of plasma proteins. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 30111543	2018
Site-Specific Glycosylation of Virion-Derived HIV-1 Env Is Mimicked by a Soluble Trimeric Immunogen. Cell reports\| PubMed ID: 30134158	2018
A Mass-Spectrometry-Based Modelling Workflow for Accurate Prediction of IgG Antibody Conformations in the Gas Phase. Angewandte Chemie (International ed. in English)\| PubMed ID: 30408305	2018
The minimum information required for a glycomics experiment (MIRAGE) project: LC guidelines. Glycobiology\| PubMed ID: 30778580	2019
In-depth structural analysis of glycans in the gas phase. Chemical science\| PubMed ID: 30809341	2019
Probing -glycoprotein microheterogeneity by lectin affinity purification-mass spectrometry analysis. Chemical science\| PubMed ID: 31183067	2019
Separation of Isomeric Glycans by Ion Mobility and Liquid Chromatography-Mass Spectrometry. Analytical chemistry\| PubMed ID: 31298840	2019
Relating glycoprotein structural heterogeneity to function - insights from native mass spectrometry. Current opinion in structural biology\| PubMed ID: 31326232	2019
Towards a standardized bioinformatics infrastructure for N- and O-glycomics. Nature communications\| PubMed ID: 31332201	2019
Separation of isomeric glycans by ion mobility spectrometry - the impact of fluorescent labelling. The Analyst\| PubMed ID: 31380551	2019
Ion Mobility-Mass Spectrometry of Glycoconjugates. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 31729663	2020
A bipartite structural organization defines the SERINC family of HIV-1 restriction factors. Nature structural & molecular biology\| PubMed ID: 31907454	2020
Quantifying Protein-Protein Interactions by Molecular Counting with Mass Photometry. Angewandte Chemie (International ed. in English)\| PubMed ID: 32167227	2020
Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides. Nature communications\| PubMed ID: 32198425	2020
Quantifying the heterogeneity of macromolecular machines by mass photometry. Nature communications\| PubMed ID: 32286308	2020
Single molecule mass photometry of nucleic acids. Nucleic acids research\| PubMed ID: 32756898	2020
Hyper-truncated Asn355- and Asn391-glycans modulate the activity of neutrophil granule myeloperoxidase. The Journal of biological chemistry\| PubMed ID: 33273015	2021
Correlating Glycoforms of DC-SIGN with Stability Using a Combination of Enzymatic Digestion and Ion Mobility Mass Spectrometry. Angewandte Chemie (International ed. in English)\| PubMed ID: 33462887	2020
Mass Photometry of Membrane Proteins. Chem\| PubMed ID: 33511302	2021
Assessing Antigen Structural Integrity through Glycosylation Analysis of the SARS-CoV-2 Viral Spike. ACS central science\| PubMed ID: 34056088	2021
Native Mass Spectrometry Meets Glycomics: Resolving Structural Detail and Occupancy of Glycans on Intact Glycoproteins. Analytical chemistry\| PubMed ID: 34279906	2021
Identification of N-glycans with GalNAc-containing antennae from recombinant HIV trimers by ion mobility and negative ion fragmentation. Analytical and bioanalytical chemistry\| PubMed ID: 34327564	2021
Label-free methods for optical characterization of protein-protein interactions. Physical chemistry chemical physics : PCCP\| PubMed ID: 34342317	2021
Formation and fragmentation of doubly and triply charged ions in the negative ion spectra of neutral N-glycans from viral and other glycoproteins. Analytical and bioanalytical chemistry\| PubMed ID: 34342671	2021
State-of-the-art glycosaminoglycan characterization. Mass spectrometry reviews\| PubMed ID: 34608657	2022
Direct observation of the molecular mechanism underlying protein polymerization. Science advances\| PubMed ID: 36044567	2022
An N-glycan on the C2 domain of JAGGED1 is important for Notch activation. Science signaling\| PubMed ID: 36219682	2022
Mass photometry reveals SARS-CoV-2 spike stabilisation to impede ACE2 binding through altered conformational dynamics. Chemical communications (Cambridge, England)\| PubMed ID: 36317551	2022
Engineer RNA-Protein Nanowires as Light-Responsive Biomaterials. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 36642821	2023
Uncovering the Role of -Glycan Occupancy on the Cooperative Assembly of Spike and Angiotensin Converting Enzyme 2 Complexes: Insights from Glycoengineering and Native Mass Spectrometry. Journal of the American Chemical Society\| PubMed ID: 37000485	2023
Measuring Protein-Protein Interactions and Quantifying Their Dissociation Constants with Mass Photometry. Current protocols\| PubMed ID: 38224147	2024