Julius Wolff Institute for Biomechanics and Musculoskeletal Regeneration
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BMPs in bone regeneration: Less is more effective, a paradigm-shift.
Cytokine & growth factor reviews Feb, 2016 | Pubmed ID: 26678813
Immune modulation as a therapeutic strategy in bone regeneration.
Journal of experimental orthopaedics Dec, 2015 | Pubmed ID: 26914869
Establishment of a preclinical ovine screening model for the investigation of bone tissue engineering strategies in cancellous and cortical bone defects.
BMC musculoskeletal disorders Mar, 2016 | Pubmed ID: 26932531
[Steel or titanium for osteosynthesis : A mechanobiological perspective].
Der Unfallchirurg Feb, 2017 | Pubmed ID: 28054122
A Pronounced Inflammatory Activity Characterizes the Early Fracture Healing Phase in Immunologically Restricted Patients.
International journal of molecular sciences Mar, 2017 | Pubmed ID: 28282868
Longitudinal change in patellofemoral cartilage thickness, cartilage T2 relaxation times, and subchondral bone plate area in adolescent vs mature athletes.
European journal of radiology Jul, 2017 | Pubmed ID: 28624016
Mechanobiologically optimized 3D titanium-mesh scaffolds enhance bone regeneration in critical segmental defects in sheep.
Science translational medicine Jan, 2018 | Pubmed ID: 29321260
Immunology Guides Skeletal Muscle Regeneration.
International journal of molecular sciences Mar, 2018 | Pubmed ID: 29534011
Clinical and Research Approaches to Treat Non-union Fracture.
Current osteoporosis reports Apr, 2018 | Pubmed ID: 29536393
Impact of Gentamicin-Loaded Bone Graft on Defect Healing in a Sheep Model.
Materials (Basel, Switzerland) Apr, 2019 | Pubmed ID: 30987272
Association between changes in molecular biomarkers of cartilage matrix turnover and changes in knee articular cartilage: a longitudinal pilot study.
Journal of experimental orthopaedics May, 2019 | Pubmed ID: 31053993
T and T mapping of the human quadriceps and patellar tendons using ultra-short echo-time (UTE) imaging and bivariate relaxation parameter-based volumetric visualization.
Magnetic resonance imaging Nov, 2019 | Pubmed ID: 31351110
Longitudinal changes in location-specific cartilage thickness and T2 relaxation-times after posterior cruciate ligament reconstruction for isolated and multiligament injury.
Clinical biomechanics (Bristol, Avon) Oct, 2020 | Pubmed ID: 31889565
The multifaceted roles of macrophages in bone regeneration: A story of polarization, activation and time.
Acta biomaterialia Oct, 2021 | Pubmed ID: 33974949
Initial mechanical conditions within an optimized bone scaffold do not ensure bone regeneration - an in silico analysis.
Biomechanics and modeling in mechanobiology Oct, 2021 | Pubmed ID: 34097188
Bursa-Derived Cells Show a Distinct Mechano-Response to Physiological and Pathological Loading .
Frontiers in cell and developmental biology , 2021 | Pubmed ID: 34136480
Surgical cup placement affects the heating up of total joint hip replacements.
Scientific reports Aug, 2021 | Pubmed ID: 34349160
Role of extracellular matrix structural components and tissue mechanics in the development of postoperative pancreatic fistula.
Journal of biomechanics Nov, 2021 | Pubmed ID: 34534790
Mice Lacking the Calcitonin Receptor Do Not Display Improved Bone Healing.
Cells Sep, 2021 | Pubmed ID: 34571953
Patient-specific resurfacing implant knee surgery in subjects with early osteoarthritis results in medial pivot and lateral femoral rollback during flexion: a retrospective pilot study.
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA Apr, 2023 | Pubmed ID: 34601628
MIF does only marginally enhance the pro-regenerative capacities of DFO in a mouse-osteotomy-model of compromised bone healing conditions.
Bone Jan, 2022 | Pubmed ID: 34743042
Dynamic Knee Joint Line Orientation Is Not Predictive of Tibio-Femoral Load Distribution During Walking.
Frontiers in bioengineering and biotechnology , 2021 | Pubmed ID: 34820363
Intramuscular and intratendinous placenta-derived mesenchymal stromal-like cell treatment of a chronic quadriceps tendon rupture.
Journal of cachexia, sarcopenia and muscle Feb, 2022 | Pubmed ID: 34985203
Enabling technologies towards personalization of scaffolds for large bone defect regeneration.
Current opinion in biotechnology Apr, 2022 | Pubmed ID: 35007988
The calcitonin receptor protects against bone loss and excessive inflammation in collagen antibody-induced arthritis.
iScience Jan, 2022 | Pubmed ID: 35036874
Reproducibility, relevance and reliability as barriers to efficient and credible biomedical technology translation.
Advanced drug delivery reviews Mar, 2022 | Pubmed ID: 35066104
A novel multipurpose device for guided knee motion and loading during dynamic magnetic resonance imaging.
Zeitschrift fur medizinische Physik Nov, 2022 | Pubmed ID: 35221155
Biomechanical Evaluation of WE43 Magnesium Plates for Mandibular Fracture Fixation.
Frontiers in bioengineering and biotechnology , 2021 | Pubmed ID: 35223813
Overstretching Expectations May Endanger the Success of the "Millennium Surgery".
Frontiers in bioengineering and biotechnology , 2022 | Pubmed ID: 35237570
The Recovery of Weight-Bearing Symmetry After Total Hip Arthroplasty Is Activity-Dependent.
Frontiers in bioengineering and biotechnology , 2022 | Pubmed ID: 35284427
Ground reaction forces and external hip joint moments predict in vivo hip contact forces during gait.
Journal of biomechanics Apr, 2022 | Pubmed ID: 35313250
The Degradation of Synthetic Polymeric Scaffolds With Strut-like Architecture Influences the Mechanics-dependent Repair Process of an Osteochondral Defect .
Frontiers in bioengineering and biotechnology , 2022 | Pubmed ID: 35360392
An in silico model predicts the impact of scaffold design in large bone defect regeneration.
Acta biomaterialia Jun, 2022 | Pubmed ID: 35417799
Source and hub of inflammation: The infrapatellar fat pad and its interactions with articular tissues during knee osteoarthritis.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Jul, 2022 | Pubmed ID: 35451170
A Comparison of Solvent-Based Extraction Methods to Assess the Central Carbon Metabolites in Mouse Bone and Muscle.
Metabolites May, 2022 | Pubmed ID: 35629956
Synchrotron-based characterization of arthroprosthetic CoCrMo particles in human bone marrow.
Journal of materials science. Materials in medicine Jun, 2022 | Pubmed ID: 35691951
High-resolution CINE imaging of active guided knee motion using continuously acquired golden-angle radial MRI and rotary sensor information.
Magnetic resonance imaging Oct, 2022 | Pubmed ID: 35777685
European Society of Biomechanics S.M. Perren Award 2022: Standardized tibio-femoral implant loads and kinematics.
Journal of biomechanics Aug, 2022 | Pubmed ID: 35803037
Treatment options for critical size defects - Comparison of different materials in a calvaria split model in sheep.
Biomaterials advances May, 2022 | Pubmed ID: 35929320
Characterizing cell recruitment into isotropic and anisotropic biomaterials by quantification of spatial density gradients .
Frontiers in bioengineering and biotechnology , 2022 | Pubmed ID: 35992332
Local immune cell contributions to fracture healing in aged individuals - A novel role for interleukin 22.
Experimental & molecular medicine Aug, 2022 | Pubmed ID: 36028760
PCL strut-like scaffolds appear superior to gyroid in terms of bone regeneration within a long bone large defect: An study.
Frontiers in bioengineering and biotechnology , 2022 | Pubmed ID: 36213070
Towards mechanobiologically optimized mandible reconstruction: CAD/CAM miniplates vs. reconstruction plates for fibula free flap fixation: A finite element study.
Frontiers in bioengineering and biotechnology , 2022 | Pubmed ID: 36466355
The decisive early phase of bone regeneration.
Nature reviews. Rheumatology Feb, 2023 | Pubmed ID: 36624263
Individual immune cell and cytokine profiles determine platelet-rich plasma composition.
Arthritis research & therapy Jan, 2023 | Pubmed ID: 36627721
Chondrocyte Isolation from Loose Bodies-An Option for Reducing Donor Site Morbidity for Autologous Chondrocyte Implantation.
International journal of molecular sciences Jan, 2023 | Pubmed ID: 36675010
Eighteen-Month Changes in Physical Activity, Body Weight, Quadriceps Strength, and Gait Biomechanics during the COVID-19 Pandemic.
Medicine and science in sports and exercise Aug, 2023 | Pubmed ID: 36921110
The enhancer landscape predetermines the skeletal regeneration capacity of stromal cells.
Science translational medicine Mar, 2023 | Pubmed ID: 36947595
Patellar tendon elastic properties derived from in vivo loading and kinematics.
Journal of biomechanics Apr, 2023 | Pubmed ID: 36948000
A comprehensive molecular profiling approach reveals metabolic alterations that steer bone tissue regeneration.
Communications biology Mar, 2023 | Pubmed ID: 36973478
Periarticular muscle status affects tibio-femoral joint loads after total knee arthroplasty.
Frontiers in bioengineering and biotechnology , 2023 | Pubmed ID: 37034264
Inactivation of the gene encoding procalcitonin prevents antibody-mediated arthritis.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] May, 2023 | Pubmed ID: 37039837
Hydrogels with stiffness-degradation spatial patterns control anisotropic 3D cell response.
Biomaterials advances Aug, 2023 | Pubmed ID: 37167748
Aging and injury affect nuclear shape heterogeneity in tendon.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Oct, 2023 | Pubmed ID: 37316467
Introduction of innovations in joint arthroplasty: Recommendations from the 'EFORT implant and patient safety initiative'.
EFORT open reviews Jul, 2023 | Pubmed ID: 37395720
Elastin stabilization prevents impaired biomechanics in human pulmonary arteries and pulmonary hypertension in rats with left heart disease.
Nature communications Jul, 2023 | Pubmed ID: 37479718
Periprosthetic Joint Infections of the Knee Lastingly Impact the Bone Homeostasis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Oct, 2023 | Pubmed ID: 37534610
Biomarkers for osteoarthritis: Current status and future prospects.
Best practice & research. Clinical rheumatology Jun, 2023 | Pubmed ID: 37620236
Improved weight bearing during gait at 6 weeks post-surgery with an angle stable locking system after distal tibial fracture.
Gait & posture Jan, 2024 | Pubmed ID: 37845132
Lower-limb internal loading and potential consequences for fracture healing.
Frontiers in bioengineering and biotechnology , 2023 | Pubmed ID: 37901836
External mechanical loading overrules cell-cell mechanical communication in sprouting angiogenesis during early bone regeneration.
PLoS computational biology Nov, 2023 | Pubmed ID: 37956208
Quantifying bone healing after mandibular displacement in orthognathic surgery.
The British journal of oral & maxillofacial surgery Jan, 2024 | Pubmed ID: 38008679
Sex- and age-related differences in the inflammatory properties of cardiac fibroblasts: impact on the cardiosplenic axis and cardiac fibrosis.
Frontiers in cardiovascular medicine , 2023 | Pubmed ID: 38054090
Biomechanical evaluation of CAD/CAM magnesium miniplates as a fixation strategy for the treatment of segmental mandibular reconstruction with a fibula free flap.
Computers in biology and medicine Jan, 2024 | Pubmed ID: 38064852
Loading of the Hip and Knee During Swimming: An in Vivo Load Study.
The Journal of bone and joint surgery. American volume Dec, 2023 | Pubmed ID: 38079507
The dual pro-inflammatory and bone-protective role of calcitonin gene-related peptide alpha in age-related osteoarthritis.
Arthritis research & therapy Dec, 2023 | Pubmed ID: 38102666
Pro-Resolving Mediators in Rotator Cuff Disease: How Is the Bursa Involved?
Cells Dec, 2023 | Pubmed ID: 38201221
External Mechanical Stability Regulates Hematoma Vascularization in Bone Healing Rather than Endothelial YAP/TAZ Mechanotransduction.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) Apr, 2024 | Pubmed ID: 38273642
Altered knee kinematics after posterior cruciate ligament single-bundle reconstruction-a comprehensive prospective biomechanical analysis.
Frontiers in bioengineering and biotechnology , 2024 | Pubmed ID: 38352697
From breast cancer cell homing to the onset of early bone metastasis: The role of bone (re)modeling in early lesion formation.
Science advances Feb, 2024 | Pubmed ID: 38381833
A two-way street - cellular metabolism and myofibroblast contraction.
NPJ Regenerative medicine Apr, 2024 | Pubmed ID: 38570493
Anastasia Polikarpova1,
Christian Bucher2,
Agnes Ellinghaus2,3,
Helena Okulski1,
Georg Duda2,
Katharina Schmidt-Bleek2,3,
Elly Margaret Tanaka1
1, Research Institute of Molecular Pathology,
2Julius Wolff Institute for Biomechanics and Musculoskeletal Regeneration, Berlin Institute of Health at Charité - Universitätsmedizin Berlin,
3Berlin Institute of Health Centre for Regenerative Therapies, Berlin Institute of Health at Charité - Universitätsmedizin Berlin
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