quantifying-drosophila-melanogaster-eye-phenotypes-computational

Quantifying <i>Drosophila melanogaster</i> Eye Phenotypes: A Computational Approach Integrating ilastik and Flynotyper

The Drosophila melanogaster compound eye is a well-structured and comprehensive array of around 800 ommatidia, exhibiting a symmetrical and hexagonal ...

University of Minnesota

In 2012, Liu et al. reported that miR-34 is an age-related miRNA regulating age-associated events and long-term brain integrity in Drosophila. They demonstrated that modulating miR-34 and its downstream target, Eip74EF, showed beneficial effects on an age-related disease using a Drosophila model of Spinocerebellar ataxia type 3 expressing SCA3trQ78. These results imply that miR-34 could be a general genetic modifier and therapeutic candidate for age-related diseases. Thus, the goal of this study was to examine the effect of miR-34 and Eip47EF on another age-related Drosophila disease model.

Madeleine R. Chalmers

Department of Pharmacy Practice and Pharmaceutical Sciences,
College of Pharmacy,
Department of Pharmacy Practice and Pharmaceutical Sciences, College of Pharmacy

University of Minnesota

Quantifying Drosophila melanogaster Eye Phenotypes: A Computational Approach Integrating ilastik and Flynotyper

Madeleine R. Chalmers

Department of Pharmacy Practice and Pharmaceutical Sciences,College of Pharmacy,Department of Pharmacy Practice and Pharmaceutical Sciences, College of Pharmacy

University of Minnesota

Quantifying Drosophila melanogaster Eye Phenotypes: A Computational Approach Integrating ilastik and Flynotyper

Department of Pharmacy Practice and Pharmaceutical Sciences,
College of Pharmacy,
Department of Pharmacy Practice and Pharmaceutical Sciences, College of Pharmacy